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Synthesis and characterization of multiphase bioactive glass-ceramics in the CaO–MgO–SiO2 system with B2O3 additive

Published online by Cambridge University Press:  31 January 2011

Xianchun Chen ,
Yan Wei ,
Zhongbing Huang ,
Yunqing Kang  and
Guangfu Yin
Xianchun Chen
Affiliation:
College of Materials Science and Engineering, Sichuan University, Chengdu 610064, People’s Republic of China
Yan Wei
Affiliation:
College of Materials Science and Engineering, Sichuan University, Chengdu 610064, People’s Republic of China
Zhongbing Huang
Affiliation:
College of Materials Science and Engineering, Sichuan University, Chengdu 610064, People’s Republic of China
Yunqing Kang
Affiliation:
College of Materials Science and Engineering, Sichuan University, Chengdu 610064, People’s Republic of China
Guangfu Yin*
Affiliation:
College of Materials Science and Engineering, Sichuan University, Chengdu 610064, People’s Republic of China
*
a)Address all correspondence to this author. e-mail: nic0700@scu.edu.cn
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Abstract

A glass-ceramic (GC0) with nominal composition of 51.2% CaO–12.1% MgO–36.7% SiO2 (wt%) was synthesized. Then multiphase glass-ceramics of MGC1 and MGC2 were obtained by adding 1 and 2 wt% B2O3 to GC0 followed by thermal treatment. The bending strength of MGC1 was the highest, about 89.46 MPa, and the coefficient of thermal expansion was 10.67 × 10−6 °C−1, closer to that of Ti–6Al–4V alloy (10.03 × 10−6 °C−1). X-ray diffraction analysis confirmed that MGC1 was predominantly composed of akermanite, merwinite, and small amounts of dicalcium silicate crystalline phases. The bioactivity and cytocompatibility in vitro of MGC1 were detected by investigating the bonelike apatite-formation ability in simulated body fluid (SBF) and osteoblast morphology and viability. The results showed that MGC1 possessed bonelike apatite-formation ability in SBF and could release ionic products to significantly stimulate cell growth and viability. Furthermore, osteoblasts adhered and spread well on MGC1, indicating good bioactivity and potential cytocompatibility.

Keywords

BiomaterialCeramicSol-gel
Type
Articles
Information
Journal of Materials Research , Volume 23 , Issue 11 , November 2008 , pp. 2873 - 2879
Copyright
Copyright © Materials Research Society 2008

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