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Intentional cognitive control impairments in schizophrenia: Generalized or specific?

Published online by Cambridge University Press:  01 November 2009

GEORGIE PAULIK ,
JOHANNA C. BADCOCK  and
MURRAY T. MAYBERY
GEORGIE PAULIK*
Affiliation:
School of Psychology, University of Western Australia, Crawley, Western Australia, Australia Schizophrenia Research Institute, Darlinghurst, New South Wales, Australia
JOHANNA C. BADCOCK
Affiliation:
Schizophrenia Research Institute, Darlinghurst, New South Wales, Australia Centre for Clinical Research in Neuropsychiatry / Graylands Hospital, Claremont, Western Australia, Australia School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Western Australia, Australia
MURRAY T. MAYBERY
Affiliation:
School of Psychology, University of Western Australia, Crawley, Western Australia, Australia
*
*Correspondence and reprint requests to: Georgie Paulik, School of Psychology, University of Western Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia. E-mail: georgiepaulik@graduate.uwa.edu.au
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Abstract

Impairments in intentional—but not unintentional—inhibition have been found in schizophrenia, and are thought to contribute to the presence of psychotic symptoms. However, it was previously unknown whether this intentional cognitive control impairment extends to intentional resistance to interference—another form of cognitive control. The current study resolved this issue through administering two cognitive control measures: one with a high intentional resistance to interference demand and the other with a high unintentional inhibition demand, to schizophrenia (n = 61) and healthy control (n = 34) participants. Consistent with previous findings, schizophrenia participants’ performance on the measures with a high unintentional inhibition demand was intact; however, they were impaired on the task with high intentional resistance to interference demands compared with controls. This latter finding suggests that intentional cognitive control impairments previously found in schizophrenia are not specific to inhibition, but instead are more general, including both processes requiring inhibition (as consistently reported in the literature) and resistance to interference (as found in the current study). (JINS, 2009, 15, 982–989.)

Keywords

SchizophreniaCognitive controlInhibitionInterferenceIntentionalUnintentional
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 15 , Issue 6 , November 2009 , pp. 982 - 989
Copyright
Copyright © The International Neuropsychological Society 2009

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