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Language and crossed finger localization in patients with schizophrenia

Published online by Cambridge University Press:  14 August 2007

TERESA M. RUSHE ,
FRANCIS A. O'NEILL  and
CIARAN MULHOLLAND
TERESA M. RUSHE
Affiliation:
School of Psychological Sciences, University of Manchester, Manchester, United Kingdom
FRANCIS A. O'NEILL
Affiliation:
Department of Mental Health, Queens University Belfast, Belfast, Northern Ireland
CIARAN MULHOLLAND
Affiliation:
Department of Mental Health, Queens University Belfast, Belfast, Northern Ireland
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Abstract

Language deficits are frequently reported in studies of patients with schizophrenia. The present study sought to test the hypothesis that such deficits are related to callosal function in this group. The FAS test of verbal fluency and Perin's Spoonerisms test of phonological processing were the tests of language. Callosal function was assessed using a Crossed Finger Localisation Test (CFLT), which is a measure of the interhemispheric transfer of somatosensory information. Patients with schizophrenia performed less well than controls on measures of language function, as well as on the CFLT. Significant positive correlations between CFLT performance and language function were present in the patient group, but not the control group. These findings extend on previous studies that report functional abnormalities of the corpus callosum in schizophrenia and are consistent with the hypothesis that language deficits in schizophrenia are related to impaired callosal functioning in this group. However, other explanations cannot be ruled out. (JINS, 2007, 13, 893–897.)

Keywords

Phonological processingCorpus callosum function interhemispheric communicationMotor dominanceVerbal fluencySomatosensory function
Type
BRIEF COMMUNICATION
Information
Journal of the International Neuropsychological Society , Volume 13 , Issue 5 , September 2007 , pp. 893 - 897
Copyright
2007 The International Neuropsychological Society

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References

REFERENCES

Beaton, A.A. (1997). The relation of planum temporale asymmetry and morphology of the corpus callosum to handedness, gender, and dyslexia: A review of the evidence. Brain and Language, 60, 155–322.Google Scholar
Beaton, A.A., Edwards, R., & Peggie, A. (2006). Dyslexia and across-hands finger localization deficits. Neuropsychologia, 40, 326–334.Google Scholar
Bokat, C.E. & Goldberg, T.E. (2004). Letter and category fluency in schizophrenia patients: A meta-analysis. Schizophrenia Research, 64, 73–78.Google Scholar
Crow, T.J. (1998). Schizophrenia as a transcallosal misconnection syndrome. Schizophrenia Research, 30, 111–114.Google Scholar
Elias, L.J., Bryden, M.P., & Bulman-Fleming, M.B. (1998). Footedness is a better predictor than is handedness of emotional lateralization. Neuropsychologia, 36, 37–43.Google Scholar
Geffen, G., Nilsson, J., Quinn, K., & Teng, E.L. (1985). The effect of lesions of the corpus callosum on finger localization. Neuropsychologia, 23, 497–514.Google Scholar
Hulshoff Pol, H.E., Schnack, H.G., Mandl, R.C.W., Cahn, W., Louis Cillins, D., Evans, A.C., & Kahn, R.S. (2004). Focal White matter density changes in schizophrenia: Reduced interhemispheric connectivity. Neuroimage, 21, 27–35.Google Scholar
Krawiecka, M., Goldberg, D., & Vaughan, M. (1977). A standardised psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatrica Scandinavica, 55, 299–308.Google Scholar
Mohr, B., Pulvermuller, F., Cohen, R., & Rockstroh, B. (2000). Interhemispheric cooperation during word processing: Evidence for callosal transfer dysfunction in schizophrenia patients. Schizophrenia Research, 46, 231–239.Google Scholar
Perin, D. (1983). Phonemic segmentation and spelling. British Journal of Psychology, 74, 129–144.Google Scholar
Powell, H.W., Parker, G.J., Alexander, D.C., Symms, M.R., Boulby, P.A., Wheeler-Kingshott, C.A., Barker, G.J., Noppeney, U., Koepp, M.J., & Duncan, J.S. (2006). Hemispheric asymmetries in language-related pathways: A combined functional MRI and tractography study. Neuroimage, 1, 388–399.Google Scholar
Rushe, T.M., Temple, C.M., Rifkin, L., Woodruff, P.W.R, Bullmore, E.T., Simmons, A., Russell, T., & Murray, R.M. (2004). Lateralization of language function in young adults born very preterm. Archives of Disease in Childhood; Fetal and Neonatal Edition, 89, F112–F118.Google Scholar
Satomi, K., Kinoshita, Y., & Hirakawa, S. (1991). Disturbances of cross localization of fingertips in a callosal patient. Cortex, 27, 327–331.Google Scholar
Satz, P. & Green, M. (1999). Atypical handedness in schizophrenia: Some methodological and theoretical issues. Schizophrenia Bulletin, 25, 63–79.Google Scholar
Seisedos, R.T., Arias, J.S., Gomez-Beneyto, M., & Cercos, C.L. (1999). Early age of onset, brain morphological changes and non-consistent motor asymmetry in schizophrenia patients. Schizophrenia Research, 37, 225–231.Google Scholar
Temple, C.M., Jeeves, M.A., & Vilarroya, O.O. (1989). Ten pen men: Explicit phonological processing in two children with callosal agenesis. Brain and Language, 37, 548–564.Google Scholar
Volpe, B.T., Siditis, J.J., Holtzman, J.D, Wilson, D.H., & Gazzaniga, M.S. (1982). Cortical mechanisms involved in praxis: Observations following partial and complete section of the corpus callosum in man. Neurology, 32, 645–650.Google Scholar
Witelson, S.T. & Nowakowski, R.S. (1991). Left out axons make men right: A hypothesis for the origin of handedness and functional asymmetry. Neuropsychologia, 29, 327–333.Google Scholar
Zaidel, D. & Sperry, R.W. (1977). Some long-term motor effects of cerebral commissurotomy in man. Neuropsychologia, 15, 193–204.Google Scholar