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A review of the infectious agents, parasites, pathogens and commensals of European cockles (Cerastoderma edule and C. glaucum)

Published online by Cambridge University Press:  30 August 2012

Matt Longshaw  and
Shelagh K. Malham
Matt Longshaw*
Affiliation:
Cefas Weymouth Laboratory, Barrack Road, The Nothe, Weymouth, Dorset, DT4 8UB
Shelagh K. Malham
Affiliation:
Bangor University, School of Ocean Sciences, Centre for Applied Marine Sciences, Menai Bridge, Anglesey, LL59 5AB
*
Correspondence should be addressed to: M. Longshaw, Cefas Weymouth Laboratory, Barrack Road, The Nothe, Weymouth, Dorset, DT4 8UB email: matt.longshaw@cefas.co.uk
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Abstract

A systematic review of the parasites, pathogens and commensals of the edible cockle (Cerastoderma edule) and of the lagoon cockle (Cerastoderma glaucum) has been completed. A total of 59 different conditions have been reported throughout the range of both of these hosts; of these 50 have been reported in edible cockles, and 28 in lagoon cockles. Cockles are hosts to viruses, bacteria, fungi (including Microsporidia), Apicomplexa, Amoeba, Ciliophora, Perkinsozoa, Haplosporidia, Cercozoa, Turbellaria, Digenea, Cestoda, Nematoda, Crustacea and Nemertea. A number of these have been reported sporadically although they may be associated with mortalities. In particular, mortalities have been associated predominately with digeneans and some protistan infections. In many cases pathology is marked in affected animals and parasites have been shown to reduce fecundity, alter burrowing behaviour and limit growth. This review provides information on the individual and population effects of these conditions as well as providing suggestions for future research. In particular, there has been a lack of taxonomic rigour applied to many studies and as a result there are a number of erroneous host records. There is a need to re-describe a number of parasite species and to determine the life cycle of those considered to be important mortality drivers.

Keywords

parasitediseasecommensalscocklesdistributiontaxonomypathology
Type
Review Article
Information
Journal of the Marine Biological Association of the United Kingdom , Volume 93 , Issue 1 , February 2013 , pp. 227 - 247
Copyright
Copyright © Crown Copyright. Published by Cambridge University Press 2012

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References

REFERENCES

Addinoa, M., Lomovaskya, B.J., Cremonte, F. and Iribarne, O. (2010) Infection by gymnophallid metacercariae enhances predation mortality of SW Atlantic stout razor clam Tagelus plebeius. Journal of Sea Research 63, 102–107.CrossRefGoogle Scholar
Aguirre-Macedo, M.L. and Kennedy, C.R. (1999) Diversity of metazoan parasites of the introduced oyster species Crassostrea gigas in the Exe Estuary. Journal of the Marine Biological Association of the United Kingdom 79, 57–63.CrossRefGoogle Scholar
Aguirre-Macedo, M.L., Sima-Alvarez, R.A., Román-Magaña, M.K. and Guemez-Ricalde, J.I. (2007) Parasite survey of the eastern oyster Crassostrea virginica in coastal lagoons of the southern Gulf of Mexico. Journal of Aquatic Animal Health 19, 270–279.CrossRefGoogle ScholarPubMed
Anderson, T.J., Hine, P.M. and Lester, R.J.G. (1995) A Steinhausia-like infection in the ovocytes of Sydney rock oysters Saccostrea commercialis. Diseases of Aquatic Organisms 22, 143–146.CrossRefGoogle Scholar
Atkins, D. (1933) Rhopalura granosa sp. nov., an orthonectid parasite of a lamellibranch Heteranomia squamula L., with a note on its swimming behaviour. Journal of the Marine Biological Association of the United Kingdom 19, 233–252.CrossRefGoogle Scholar
Atkins, D. (1934) Two parasites of the common cockle Cardium edule: a rhabdocoele Paravortex cardii Hallez and a copepod Paranthessius rostratus. Journal of the Marine Biological Association of the United Kingdom 19, 669–676.CrossRefGoogle Scholar
Atkins, D. (1954) Further notes on a marine member of the Saprolegniaceae, Leptolegnia marina n. sp., infecting certain invertebrates. Journal of the Marine Biological Association of the United Kingdom 33, 613–625.CrossRefGoogle Scholar
Audemard, C., Le Roux, F., Barnaud, A., Collins, C., Sautour, B., Sauriau, P.-G., de Montaudouin, X., Coustau, C., Combes, C. and Berthe, F. (2002) Needle in a haystack: involvement of the copepod Paracartia grani in the life-cycle of the oyster pathogen Marteilia refringens. Parasitology 124, 315–323.CrossRefGoogle Scholar
Auffret, M. and Poder, M. (1987) Pathology of the main bivalve mollusc species from oyster rearing areas in Brittany (France). Aquaculture 67, 255–257.CrossRefGoogle Scholar
Azevedo, C. (1993) Occurrence of an unusual branchial mycoplasma-like infection in cockle Cerastoderma edule (Mollusca, Bivalvia). Diseases of Aquatic Organisms 16, 55–59.CrossRefGoogle Scholar
Azevedo, C. (1997) Some observations on an amoeba, destructive agent of the gills of Cerastoderma edule (Mollusca, Bivalvia). Diseases of Aquatic Organisms 30, 223–225.CrossRefGoogle Scholar
Azevedo, C. and Cachola, R. (1992) Fine structure of the apicomplexa oocyst of Nematopsis sp. of two marine bivalve mollusks. Diseases of Aquatic Organisms 14, 69–73.CrossRefGoogle Scholar
Azevedo, C. and Canning, E.U. (1987) Ultrastructure of a microsporidian hyperparasite, Unikaryon legeri (Microsporida), of trematode larvae. Journal of Parasitology 73, 214–223.CrossRefGoogle ScholarPubMed
Azevedo, C., Conchas, R.F. and Montes, J. (2003) Description of Haplosporidium edule n. sp. (Phylum Haplosporidia), a parasite of Cerastoderma edule (Mollusca, Bivalvia) with complex spore ornamentation. European Journal of Protistology 39, 161–167.CrossRefGoogle Scholar
Azevedo, C. and Villalba, A. (1991) Extracellular giant rickettsiae associated with bacteria in the gill of Crassostrea gigas (Mollusca, Bivalvia). Journal of Invertebrate Pathology 58, 75–81.CrossRefGoogle Scholar
Babarro, J.M.F. and de Zwaan, A. (2001) Factors involved in the (near) anoxic survival time of Cerastoderma edule: associated bacteria vs. endogenous fuel. Comparative Biochemistry and Physiology—C: Toxicology and Pharmacology 128, 325–337.Google ScholarPubMed
Babarro, J.M.F. and de Zwaan, A. (2008) Anaerobic survival potential of four bivalves from different habitats. A comparative survey. Comparative Biochemistry and Physiology—A: Molecular and Integrative Physiology 151, 108–113.CrossRefGoogle ScholarPubMed
Barber, B.J. (2004) Neoplastic diseases of commercially important marine bivalves. Aquatic Living Resources 17, 449–466.CrossRefGoogle Scholar
Bartoli, P. (1983) Gymnophallus rebecqui n. sp. (syn. Parvatrema sp. 1, J. Rebecq, 1964) (Digenea: Gymnophallidae), an intestinal parasite of ducks from Camargue (France). Annales de Parasitologie Humaine et Comparée 58, 211–225.CrossRefGoogle Scholar
Bartoli, P. and Gibson, D.I. (2007) Synopsis of the life cycles of Digenea (Platyhelminthes) from lagoons of the northern coast of the western Mediterranean. Journal of Natural History 41, 1553–1570.CrossRefGoogle Scholar
Bartoli, P., Jousson, O. and Russell-Pinto, F. (2000) The life cycle of Monorchis parvus (Digenea: Monorchidae) demonstrated by developmental and molecular data. Journal of Parasitology 86, 479–489.CrossRefGoogle Scholar
Baudrimont, M. and de Montaudouin, X. (2007) Evidence of an altered protective effect of metallothioneins after cadmium exposure in the digenean parasite-infected cockle (Cerastoderma edule). Parasitology 134, 237–245.CrossRefGoogle ScholarPubMed
Baudrimont, M., de Montaudouin, X. and Palvadeau, A. (2006) Impact of digenean parasite infection on metallothionein synthesis by the cockle (Cerastoderma edule): a multivariate field monitoring. Marine Pollution Bulletin 52, 494–502.CrossRefGoogle ScholarPubMed
Becker, C. and Türkay, M. (2010) Taxonomy and morphology of European pea crabs (Crustacea: Brachyura: Pinnotheridae). Journal of Natural History 44, 1555–1575.CrossRefGoogle Scholar
Belofastova, I.P. (1996) Gregarines of the genus Nematopsis (Eugregarinida: Porosporidae), parasites of the Black Sea molluscs. Parazitologiya 30, 159–173.Google Scholar
Belofastova, I.P. and Dmitrieva, E.V. (1999) The turbellarians of genus Paravortex (Rhabdocoela: Graffillidae)—parasites of the Black Sea bivalves. Ecologiya Morya 48, 76–78.Google Scholar
Bierbaum, R.M. and Ferson, S. (1986) Do symbiotic pea crabs decrease growth rate in mussels? Biological Bulletin. Marine Biological Laboratory, Woods Hole 170, 51–61.CrossRefGoogle Scholar
Blanchet, H., Raymond, N., de Montaudouin, X., Capdepuy, M. and Bachelet, G. (2003) Effects of digenean trematodes and heterotrophic bacteria on mortality and burying capability of the common cockle Cerastoderma edule (L.). Journal of Experimental Marine Biology and Ecology 293, 89–105.CrossRefGoogle Scholar
Bowers, E.A. (1969) Cercaria bucephalopsis haimeana (Lacaze-Duthiers, 1854) (Digenea: Bucephalidae) in the cockle, Cardium edule L. in South Wales. Journal of Natural History 3, 409–422.CrossRefGoogle Scholar
Bowers, E.A., Bartoli, P.Russell-Pinto, F. and James, B.L. (1996) The metacercariae of sibling species of Meiogymnophallus, including M. rebequi comb. nov. (Digenea: Gymnophallidae), and their effects on closely related Cerastoderma host species (Mollusca: Bivalvia). Parasitology Research 82, 505–510.CrossRefGoogle Scholar
Bowers, E.A. and James, B.L. (1967) Studies on the morphology, ecology and life-cycle of Meiogymnophallus minutus (Cobbold, 1859) comb. nov. (Trematoda: Gymnophallidae). Parasitology 57, 281–300.CrossRefGoogle ScholarPubMed
Bowmer, T., Jenner, H.A., Foekema, E. and Van der Meer, M. (1994) The detection of chronic biological effects in the marine intertidal bivalve Cerastoderma edule, in model ecosystem studies with pulverised fuel ash: reproduction and histopathology. Environmental Pollution 85, 191–204.CrossRefGoogle ScholarPubMed
Boyden, C.R. (1970) Comparative studies of Cerastoderma edule (L.) and Cerastoderma glaucum (Poiret). PhD thesis. University of London, United Kingdom.Google Scholar
Boyden, C.R. (1971) A comparative study of the reproductive cycles of the cockles Cerastoderma edule and C. glaucum. Journal of the Marine Biological Association of the United Kingdom 51, 605–622.CrossRefGoogle Scholar
Brusa, F., Ponce de Leon, R. and Damborenea, C. (2006) A new Paravortex (Platyhelminthes, Dalyellioida) endoparasite of Mesodesma mactroides (Bivalvia, Mesodesmatidae) from Uruguay. Parasitology Research 99, 566–571.CrossRefGoogle ScholarPubMed
Buck, B.H., Thieltges, D.W., Walter, U., Nehls, G. and Rosenthal, H. (2005) Inshore–offshore comparison of parasite infestation in Mytilus edulis: implications for open ocean aquaculture. Journal of Applied Ichthyology 21, 107–113.CrossRefGoogle Scholar
Burreson, E.M. and Ford, S.E. (2004) A review of recent information on the Haplosporidia, with special reference to Haplosporidium nelsoni (MSX disease). Aquatic Living Resources 17, 499–517.CrossRefGoogle Scholar
Cable, R.M. (1953) The life cycle of Parvatrema borinqueñae gen. et sp. nov. (Trematoda: Digenea) and the systematic position of the subfamily Gymnophallinae. Journal of Parasitology 39, 408–421.CrossRefGoogle ScholarPubMed
Cajaraville, M.P. and Angulo, E. (1991) Chlamydia-like organisms in digestive and duct cells of mussels from the Basque coast. Journal of Invertebrate Pathology 58, 381–386.CrossRefGoogle ScholarPubMed
Campbell, D. (1985) The life cycle of Gymnophallus rebecqui (Digenea: Gymnophallidae) and the response of the bivalve Abra tenuis to its metacercariae. Journal of the Marine Biological Association of the United Kingdom 65, 589–601.CrossRefGoogle Scholar
Canning, E.U. and Nicholas, J.P. (1974) Light and electron microscope observations on Unikaryon legeri (Microsporida, Nosematidae), a parasite of the metacercaria of Meiogymnophallus minutus in Cardium edule. Journal of Invertebrate Pathology 23, 92–100.CrossRefGoogle Scholar
Carballal, M.J., Diaz, S. and Villalba, A. (2005) Urosporidium sp. hyperparasite of the turbellarian Paravortex cardii in the cockle Cerastoderma edule. Journal of Invertebrate Pathology 90, 104–107.CrossRefGoogle ScholarPubMed
Carballal, M.J., Iglesias, D., Santamarina, J., Ferro-Soto, B. and Villalba, A. (2001) Parasites and pathologic conditions of the cockle Cerastoderma edule populations of the coast of Galicia (NW Spain). Journal of Invertebrate Pathology 78, 87–97.CrossRefGoogle ScholarPubMed
Carballal, M.J., Villalba, A., Iglesias, D. and Hine, P.M. (2003) Virus-like particles associated with large foci of heavy hemocytic infiltration in cockles Cerastoderma edule from Galicia (NW Spain). Journal of Invertebrate Pathology 84, 234–237.CrossRefGoogle ScholarPubMed
Carrasco, N., Arzul, I., Chollet, B., Robert, M., Joly, J.P., Furones, M.D. and Berthe, F.C.J. (2008) Comparative experimental infection of the copepod Paracartia grani with Marteilia refringens and Marteilia maurini. Journal of Fish Diseases 31, 497–504.CrossRefGoogle ScholarPubMed
Carrasco, N., Roque, A., Andree, K.B., Rodgers, C., Lacuesta, B. and Furones, M.D. (2011) A Marteilia parasite and digestive epithelial virosis lesions observed during a common edible cockle Cerastoderma edule mortality event in the Spanish Mediterranean coast. Aquaculture 321, 197–202.CrossRefGoogle Scholar
Carrasco, N., Andree, K.B., Lacuesta, B., Roque, A., Rodgers, C. and Furones, M.D. (2012) Molecular characterization of the Marteilia parasite infecting the common edible cockle Cerastoderma edule in the Spanish Mediterranean coast: a new Marteilia species affecting bivalves in Europe? Aquaculture 324–325, 20–26.CrossRefGoogle Scholar
Chai, J.Y., Han, E.T., Choi, D., Seo, M., Kim, J.L., Guk, S.M., Shin, E.H. and Lee, S.H. (2007) A new gymnophallid trematode from the intestine of mice infected with metacercariae from the razor clam Sinonovacula constricta. Journal of Parasitology 93, 132–137.CrossRefGoogle ScholarPubMed
Chao, P.-P. (2000) Taxonomic studies on the shells, allozymes and parasites of European cockles in the Cerastoderma edule (L.) and Cerastoderma glaucum (Bruguière) species complex. PhD thesis. University of Wales, Swansea, United Kingdom.Google Scholar
Cheng, T.C. and Burton, R.W. (1965) Relationships between Bucephalus sp. and Crassostrea virginica: histopathology and sites of infection. Chesapeake Science 6, 3–16.CrossRefGoogle Scholar
Ching, H.L. (1995) Evaluation of characters of the digenean family Gymnophallidae Morozov, 1955. Canadian Journal of Fisheries and Aquatic Sciences 52, 78–83.CrossRefGoogle Scholar
Clopton, R.E. (2002) Phylum Apicomplexa Levine, 1970: Order Eugregarinorida Léger, 1900. In Lee, J.J., Leedale, G., Patterson, D. and Bradbury, P.C. (eds) Illustrated guide to the protozoa. Lawrence, KS: Society of Protozoologists, pp. 205–288.Google Scholar
Cole, H.A. (1956) Benthos and the shellfish of commerce. In Graham, M. (ed.) Sea fisheries. Their investigation in the United Kingdom. London: Edward Arnold (Publishers) Ltd, pp. 139–206.Google Scholar
Collins, C.M. and Mulcahy, M.F. (2003) Cell-free transmission of a haemic neoplasm in the cockle Cerastoderma edule. Diseases of Aquatic Organisms 54, 61–67.CrossRefGoogle ScholarPubMed
Comps, M., Grizel, H., Tige, G. and Duthoit, J.-L. (1975) Parasites nouveaux de la glande digestive des mollusques marins Mytilus edulis L. et Cardium edule L. Comptes Rendus Académie des Sciences de Paris (Séries D) 281, 179–181.Google Scholar
Comtet, T., Garcia, C., Le Coguic, Y. and Joly, J.-P. (2003) Infection of the cockle Cerastoderma edule in the Baie des Veys (France) by the microsporidian Steinhausia sp. Diseases of Aquatic Organisms 57, 135–139.CrossRefGoogle ScholarPubMed
Costanzo, G. and Calafiore, N. (1985) Larval development of Herrmannella rostrata Canu, 1891 (Copepoda, Poecilostomatoida, Sabelliphilidae) of the Lake Faro (Messina) reared in the laboratory. Memorie di Biologia Marina e di Oceanografia 15, 141–154.Google Scholar
Cremonte, F. (2001) Bartolius pierrei n. g., n. sp. (Digenea: Gymnophallidae) from the Peninsula Valdes, Argentina. Systematic Parasitology 49, 139–147.CrossRefGoogle Scholar
Cremonte, F. and Ituarte, C. (2003) Pathologies elicited by the gymnophallid metacercariae of Bartolius pierrei in the clam Darina solenoides. Journal of the Marine Biological Association of the United Kingdom 83, 311–318.CrossRefGoogle Scholar
Cremonte, F., Vázquez, N. and Ituarte, C. (2008) The development of Gymnophallus australis Szidat, 1962 (Digenea: Gymnophallidae) from the Patagonian coast (Argentina) from metacercaria to adult, with an amended diagnosis of Gymnophallus Odhner, 1905. Systematic Parasitology 69, 23–31.CrossRefGoogle ScholarPubMed
Culurgioni, J., D'Amico, V., De Murtas, R., Trotti, G.C. and Figus, V. (2006) Parasitological monitoring of commercial native bivalves from St. Gilla lagoon (Sardinia, South Western Mediterranean). Ittiopatologia 3, 243–252.Google Scholar
de Montaudouin, X., Jensen, K.T., Desclaux, C., Wegeberg, A.M. and Sajus, M.C. (2005) Effect of intermediate host size (Cerastoderma edule) on infectivity of cercariae of Himasthla quissetensis (Echinostomatidae: Trematoda). Journal of the Marine Biological Association of the United Kingdom 85, 809–812.CrossRefGoogle Scholar
de Montaudouin, X., Kisielewski, I., Bachelet, G. and Desclaux, C. (2000) A census of macroparasites in an intertidal bivalve community, Arcachon Bay, France. Oceanologica Acta 23, 453–468.CrossRefGoogle Scholar
de Montaudouin, X., Thieltges, D.W., Gam, M., Krakau, M., Pina, S., Bazairi, H., Dabouineau, L., Russell-Pinto, F. and Jensen, K.T. (2009) Digenean trematode species in the cockle Cerastoderma edule: identification key and distribution along the north-eastern Atlantic shoreline. Journal of the Marine Biological Association of the United Kingdom 89, 543–556.CrossRefGoogle Scholar
de Montaudouin, X., Wegeberg, A.M., Jensen, K.T. and Sauriau, P.G. (1998) Infection characteristics of Himasthla elongata cercariae in cockles as a function of water current. Diseases of Aquatic Organisms 34, 63–70.CrossRefGoogle Scholar
de Zwaan, A., Babarro, J.M.F., Monari, M. and Cattani, O. (2002) Anoxic survival potential of bivalves: (arte)facts. Comparative Biochemistry and Physiology—A: Molecular and Integrative Physiology 131, 615–624.CrossRefGoogle ScholarPubMed
Deltreil, J.-P. and His, E. (1970) Sur la présence d'une cercaire de trématode chez Cardium edule L. dans le bassin d'Arcachon. Revue des Travaux de l'Institut des Pêches Maritimes 34, 225–232.Google Scholar
Derbali, A., Jarboui, O. and Ghorbel, M. (2009) Reproductive biology of the cockle Cerastoderma glaucum (Mollusca: Bivalvia) from the north coast of Sfax (Gulf of Gabes, Tunisia). Ciencas Marinas 35, 141–152.CrossRefGoogle Scholar
Desclaux, C., de Montaudouin, X. and Bachelet, G. (2002) Cockle emergence at the sediment surface: ‘favourization’ mechanism by digenean parasites? Diseases of Aquatic Organisms 52, 137–149.CrossRefGoogle ScholarPubMed
Desclaux, C., de Montaudouin, X. and Bachelet, G. (2004) Cockle Cerastoderma edule population mortality: role of the digenean parasite Himasthla quissetensis. Marine Ecology Progress Series 279, 141–150.CrossRefGoogle Scholar
Desclaux, C., Russell-Pinto, F., de Montaudouin, X. and Bachelet, G. (2006) First record and description of metacercariae of Curtuteria arguinae n. sp. (Digenea: Echinostomatidae), parasite of cockles Cerastoderma edule (Mollusca: Bivalvia) in Arcachon Bay, France. Journal of Parasitology 92, 578–587.CrossRefGoogle Scholar
Díaz, S., Cao, A., Villalba, A. and Carballal, M.J. (2010) Expression of mutant protein p53 and Hsp70 and Hsp90 chaperones in cockles Cerastoderma edule affected by neoplasia. Diseases of Aquatic Organisms 90, 219–226.CrossRefGoogle ScholarPubMed
Dolgikh, A.V. (1968) The lifecycle of Parvatrema isostoma Belopol'skaja, 1966 (Trematoda, Gymnophallidae). Doklady Akademii Nauk SSSR 183, 1229–1231.Google Scholar
Dubois, S.Y., Savoye, N., Sauriau, P.G., Billy, I., Martinez, P. and de Montaudouin, X. (2009) Digenean trematodes–marine mollusc relationships: a stable isotope study. Diseases of Aquatic Organisms 84, 65–77.CrossRefGoogle ScholarPubMed
Ducrotoy, J.P., Rybarczyk, H., Souprayen, J., Bachelet, G., Beukema, J.J., Desprez, M., Dörjes, J., Essink, K., Guillou, J., Michaelis, H., Sylvand, B., Wilson, J.G., Elkaïm, B. and Ibanez, F. (1989) A comparison of the population dynamics of the cockle (Cerastoderma edule, L.) in north-western Europe. Proceedings of the Estuarine and Coastal Sciences Association Symposium 19, 173–184.Google Scholar
Engelsma, M.Y., Roozenburg, I., Voorbergen-Laarman, M., Van den Brink, A., Troost, K., Ysebaert, T., Bateman, K. and Longshaw, M. (2011) Digenean trematodes and haplosporidian protozoans associated with summer mortality of cockles Cerastoderma edule in the Oosterschelde, The Netherlands. In European Association of Fish Pathologists Conference, Split, Croatia, 14–18 September 2011 (Abstract).Google Scholar
Faasse, M.A. (2003) Copepods associated with marine invertebrates in the Netherlands (Crustacea: Copepoda). Nederlandse Faunistische Mededelingen 19, 79–86.Google Scholar
Faliex, E. and Morand, S. (1994) Population dynamics of the metacercarial stage of the bucephalid trematode, Labratrema minimus (Stossich, 1887) from Salses-Leucate lagoon (France) during cercarial shedding period. Journal of Helminthology 68, 35–40.CrossRefGoogle ScholarPubMed
Faliex, E., Pagès, J.R. and Combes, C. (2003) Circulation du trématode Labratrema minimus dans un écosystème lagunaire: stratégie de retour à l'hôte définitif. In Combes, C. and Jourdane, J. (eds) Taxonomy, ecology and evolution of metazoan parasites. Perpignan, France: Presses Universitaires de Perpignan, pp. 321–345.Google Scholar
Feist, S.W., Hine, P.M., Bateman, K.S., Stentiford, G.D. and Longshaw, M. (2009) Paramarteilia canceri sp. n. (Cercozoa) in the European edible crab (Cancer pagurus) with a proposal for the revision of the order Paramyxida Chatton, 1911. Folia Parasitologica 56, 73–85.CrossRefGoogle Scholar
Fenchel, T. (1965) Ciliates from Scandinavian molluscs. Ophelia 2, 71–174.CrossRefGoogle Scholar
Fermer, J., Culloty, S.C., Kelly, T.C. and O'Riordan, R.M. (2009) Intrapopulational distribution of Meiogymnophallus minutus (Digenea, Gymnophallidae) infections in its first and second intermediate host. Parasitology Research 105, 1231–1238.CrossRefGoogle ScholarPubMed
Fermer, J., Culloty, S.C., Kelly, T.C. and O'Riordan, R.M. (2010) Temporal variation of Meiogymnophallus minutus infections in the first and second intermediate host. Journal of Helminthology 84, 362–368.CrossRefGoogle ScholarPubMed
Fermer, J., Culloty, S.C., Kelly, T.C. and O'Riordan, R.M. (2011) Manipulation of Cerastoderma edule burrowing ability by Meiogymnophallus minutus metacercariae? Journal of the Marine Biological Association of the United Kingdom 91, 907–911.CrossRefGoogle Scholar
Figus, V., Culurgioni, J., De Murtas, R. and Trotti, G.C. (2006) Parasites of Cerastoderma glaucum (Poiret, 1879) (Bivalvia: Cardiidae) from St. Gilla lagoon, Southern Sardinia. Ittiopatologia 3, 69–74.Google Scholar
Fischer, W.M. and Palmer, J.D. (2005) Evidence from small-subunit ribosomal RNA sequences for a fungal origin of Microsporidia. Molecular Phylogenetics and Evolution 36, 606–622.CrossRefGoogle ScholarPubMed
Ford, S.E., Stokes, N.A., Burreson, E.M., Scarpa, E., Carnegie, R.B., Kraeuter, J.N. and Bushek, D. (2009) Minchinia mercenariae n. sp. (Haplosporidia) in the hard clam Mercenaria mercenaria: implications of a rare parasite in a commercially important host. Journal of Eukaryotic Microbiology 56, 542–551.CrossRefGoogle Scholar
Francisco, C.J., Almeida, A., Castro, A.M., Pina, S., Russell-Pinto, F., Rodrigues, P. and Santos, M.J. (2010a) Morphological and molecular analysis of metacercariae of Diphtherostomum brusinae (Stossich, 1888) Stossich, 1903 from a new bivalve host Mytilus galloprovincialis. Journal of Helminthology 85, 179–184.CrossRefGoogle ScholarPubMed
Francisco, C.J., Hermida, M.A. and Santos, M.J. (2010b) Parasites and symbionts from Mytilus galloprovincialis (Lamark, 1819) (Bivalves: Mytilidae) of the Aveiro estuary Portugal. Journal of Parasitology 96, 200–205.CrossRefGoogle ScholarPubMed
Gam, M., Bazaïri, H., Jensen, K.T. and de Montaudouin, X. (2008) Metazoan parasites in an intermediate host population near its southern border: the common cockle (Cerastoderma edule) and its trematodes in a Moroccan coastal lagoon (Merja Zerga). Journal of the Marine Biological Association of the United Kingdom 88, 357–364.CrossRefGoogle Scholar
Gee, J.M. and Davey, J.T. (1986) Experimental studies on the infestation of Mytilus edulis (L.) by Mytilicola intestinalis Steuer (Copepoda, Cyclopoida). Journal du Conseil International pour l'Exploration de la Mer 42, 265–271.CrossRefGoogle Scholar
Ghimire, T.J. (2010) Redescription of genera of Family Eimeriidae Minchin, 1903. International Journal for Life Sciences 4, 26–47.CrossRefGoogle Scholar
Gibson, R. (1967) Occurrence of the entocommensal rhynchocoelan, Malacobdella grossa, in the oval piddock, Zirfaea crispata, on the Yorkshire coast. Journal of the Marine Biological Association of the United Kingdom 47, 301–317.CrossRefGoogle Scholar
Gibson, R. and Jennings, J.B. (1969) Observations on the diet, feeding mechanisms, digestion and food reserves of the entocommensal rhynchocoelan Malacobdella grossa. Journal of the Marine Biological Association of the United Kingdom 49, 17–32.CrossRefGoogle Scholar
Gill, E.E. and Fast, N.M. (2006) Assessing the microsporidia–fungi relationship: combined phylogenetic analysis of eight genes. Gene 375, 103–109.CrossRefGoogle ScholarPubMed
Goater, C.P. (1993) Population biology of Meiogymnophallus minutus (Trematoda: Gymnophallidae) in cockles Cerastoderma edule from the Exe estuary, England. Journal of the Marine Biological Association of the United Kingdom 73, 163–177.CrossRefGoogle Scholar
Gulyaev, V.D. (2008) Evolution of cestode life cycles. Zoologičeskij Žhurnal 87, 1411–1419.Google Scholar
Hancock, D.A. (1970) The role of predators and parasites in a fishery for the mollusc Cardium edule L. In den Boer, P.J. and Gradwell, G.R. (eds) Proceedings of the Advanced Study Institute on ‘Dynamics of Numbers in Populations’, pp. 419–439.Google Scholar
Hancock, D.A. and Urquhart, A.E. (1965) The determination of natural mortality and its causes in an exploited population of cockles (Cardium edule L.). Fishery Investigations 24, 1–40.Google Scholar
Hirt, R.P., Logsdon, J.M., Healy, B., Dorey, M.W., Doolittle, W.F. and Embley, T.M. (1999) Microsporidia are related to fungi: evidence from the largest subunit of RNA polymerase II and other proteins. Proceedings of the National Academy of Sciences of the United States of America 96, 580–585.CrossRefGoogle ScholarPubMed
Holland, N.D. and Wilson, N.G. (2009) Molecular identification of larvae of a tetraphyllidean tapeworm (Platyhelminthes: Eucestoda) in a razor clam as an alternative intermediate host in the life cycle of Acanthobothrium brevissime. Journal of Parasitology 95, 1215–1217.CrossRefGoogle Scholar
Hopkins, S.H. (1954) The American species of trematode confused with Bucephalus (bucephalopsis) haimeanus. Parasitology 44, 353–370.CrossRefGoogle ScholarPubMed
Horn, M. (2008) Chlamydiae as symbionts in eukaryotes. Annual Review of Microbiology 62, 113–131.CrossRefGoogle ScholarPubMed
Huet, L. (1888) Note sur une parasite nouveau du Cardium edule. Bulletin de la Société Linnéene de Normandie 4, 149–152.Google Scholar
James, B.L. (1964) The lifecycle of Parvatrema homoeotecnum sp. nov. (Trematoda: Digenea) and a review of the family Gymnophallidae Morozov, 1955. Parasitology 54, 1–41.CrossRefGoogle Scholar
James, B.L. and Bowers, E.A. (1967a) The effects of parasitism by the daughter sporocysts of Cercaria bucephalopsis haimaena Lacaze-Duthiers, 1854, on the digestive tubules of the cockle, Cardium edule L. Parasitology 57, 67–77.CrossRefGoogle Scholar
James, B.L. and Bowers, E.A. (1967b) Histochemical observations on the occurrence of carbohydrates, lipids and enzymes in the daughter sporocyst of Cercaria bucephalopsis haimaena Lacaze-Duthiers, 1854 (Digenea: Bucephalidae). Parasitology 57, 79–86.CrossRefGoogle Scholar
James, B.L., Bowers, E.A. and Richards, J.G. (1966) The ultrastructure of the daughter sporocyst of Cercaria bucephalopsis haimeana Lacaze-Duthiers, 1854 from the edible cockle, Cardium edule L. Parasitology 56, 753–762.CrossRefGoogle ScholarPubMed
James, B.L., Sannia, A. and Bowers, E.A. (1977) Parasites of birds and shellfish. Problems of a small estuary. In Nelson-Smith, A. and Bridges, E.M. (eds) Proceedings of the Symposium on the Burry Inlet (South Wales) held at the University College of Swansea, pp. 1–16.Google Scholar
Javanshir, A. (2001a) Influence of infestation by Labratrema minimus (Bucephalidae: Digenea) on oxygen consumption of edible cockle Cerastoderma edule (Mollusc: Bivalvia) in laboratory conditions. Iranian Journal of Fisheries Science 3, 39–54.Google Scholar
Javanshir, A. (2001b) Influence of Labratrema minutus (Trematoda: Digenea) on filtration rate performance of edible cockle Cerastoderma edule in the extreme temperature and salinity conditions (an in vitro experiment). Iranian Journal of Fisheries Science 3, 73–94.Google Scholar
Javanshir, A., Seyfabadi, S.J., Bachelet, G. and Feghhi, J. (2007) Impact of two parasitic trematodes, Meiogymnophallus minutus and Himasthla spp., on the growth of cockle, Cerastoderma edule. Iranian Journal of Fisheries Science 6, 33–58.Google Scholar
Jensen, K.T., Castro, N.F. and Bachelet, G. (1999) Infectivity of Himasthla spp. (Trematoda) in cockle (Cerastoderma edule) spat. Journal of the Marine Biological Association of the United Kingdom 79, 265–271.CrossRefGoogle Scholar
Jones, A.M., Jones, Y.M. and James, J.L. (1979) The incidence of the nemertine Malacobdella grossa in the bivalve Cerastoderma edule in Shetland. Journal of the Marine Biological Association of the United Kingdom 59, 373–375.CrossRefGoogle Scholar
Jonsson, P.R. and André, C. (1992) Mass-mortality of the bivalve Cerastoderma edule (Linnaeus) on the Swedish west coast caused by infestation with the digenean trematode Cercaria cerastodermae I. Ophelia 36, 151–157.CrossRefGoogle Scholar
Kesting, V., Gollasch, S. and Zander, C. (1996) Parasite communities of the Schlei Fjord (Baltic coast of northern Germany). Helgoland Marine Research 50, 477–496.Google Scholar
Kim, Y. and Powell, E.N. (2007) Distribution of parasites and pathologies in sentinel bivalves: NOAA Status and Trends ‘Mussel Watch’ Program. Journal of Shellfish Research 26, 1115–1151.CrossRefGoogle Scholar
Kniskern, V.B. (1952) Studies on the trematode Family Bucephalidae Poche, 1907: Part I. A systematic review of the Family Bucephalidae. Transactions of the American Microscopical Society 71, 253–266.CrossRefGoogle Scholar
Kruczynski, W.L. (1972) The effect of the pea crab, Pinnotheres maculatus Say, on growth of the bay scallop, Argopecten irradians concentricus (Say). Chesapeake Science 13, 218–220.CrossRefGoogle Scholar
Lacaze-Duthiers, F.J.H. (1854) Mémoire sur le bucéphale haime (Bucephalus haimeanus), helminthe parasite des huitres et des bucardes. Annales des Sciences Naturelles Paris (Zoologie) 4, 294–302.Google Scholar
Landsberg, J.H. (1996) Neoplasia and biotoxins in bivalves: is there a connection? Journal of Shellfish Research 15, 203–230.Google Scholar
Lassalle, G., de Montaudouin, X., Soudant, P. and Paillard, C. (2007) Parasite co-infection of two sympatric bivalves, the Manila clam (Ruditapes philippinarum) and the cockle (Cerastoderma edule) along a latitudinal gradient. Aquatic Living Resources 20, 33–42.CrossRefGoogle Scholar
Lauckner, G. (1971) Zur trematodenfauna der herzmuscheln Cardium edule und Cardium lamarcki. Helgoländer Meeresuntersuchungen 22, 377–400.CrossRefGoogle Scholar
Lauckner, G. (1984) Impact of trematode parasitism on the fauna of a North Sea tidal flat. Helgoländer Meeresuntersuchungen 37, 185–199.CrossRefGoogle Scholar
Le Grand, F., Kraffe, E., de Montaudouin, X., Villalba, A., Marty, Y. and Soudant, P. (2010) Prevalence, intensity, and aneuploidy patterns of disseminated neoplasia in cockles (Cerastoderma edule) from Arcachon Bay: seasonal variation and position in sediment. Journal of Invertebrate Pathology 104, 110–118.CrossRefGoogle ScholarPubMed
Lebour, M.V. (1912) A review of British marine cercariae. Parasitology 4, 416–456.CrossRefGoogle Scholar
Lebour, M.V. and Elmhirst, R. (1922) A contribution towards the life history of Parorchis acanthus Nicoll, a trematode in the herring gull. Journal of the Marine Biological Association of the United Kingdom 12, 829–832.CrossRefGoogle Scholar
Leigh-Sharpe, W.H. (1933) Note on the occurrence of Graffilla gemellipara Linton (Turbellaria) at Plymouth. Parasitology 25, 108.CrossRefGoogle Scholar
López-Flores, I., Garrido-Ramos, M.A., de la Herran, R., Ruiz-Rejón, C., Ruiz-Rejón, M. and Navas, J.I. (2008) Identification of Marteilia refringens infecting the razor clam Solen marginatus by PCR and in situ hybridization. Molecular and Cellular Probes 22, 151–155.CrossRefGoogle ScholarPubMed
Maeno, Y., Yurimoto, T., Nasu, H., Ito, S., Aishima, N., Matsuyama, T., Kamaishi, T., Oseko, N. and Watanabe, Y. (2006) Virus-like particles associated with mass mortalities of the pen shell Atrina pectinata in Japan. Diseases of Aquatic Organisms 71, 169–173.CrossRefGoogle ScholarPubMed
Maillard, C. (1975a) Evolutive cycle of Paratimonia gobii, Prevot and Bartoli 1967 (Trematoda, Monorchiidea). Acta Tropica 32, 327–339.Google ScholarPubMed
Maillard, C. (1975b) Labratrema lamirandi (Carrère, 1937) (Trematoda: Bucephalidae) parasite de Dicentrarchus labrax (L. 1758). Creation du genre Labratrema. Cycle evolutif. Bulletin de la Muséum National d'Historie Naturalle, Paris, Zoologie 193, 69–80.Google Scholar
Maillard, C. and Saad-Fares, A. (1981) Bucephalus baeri n. sp. (Trematoda) parasite de Dicentrarchus labrax (Teleostei): description et cycle évolutif. Parasitology Research 66, 31–40.Google Scholar
Matthews, R.A. (1973) The life-cycle of Bucephalus haimeanus Lacaze-Duthiers, 1854 from Cardium edule L. Parasitology 67, 341–350.CrossRefGoogle ScholarPubMed
McDermott, J.J. (2006) Nemerteans as hosts for symbionts: a review. Journal of Natural History 40, 1007–1020.CrossRefGoogle Scholar
Mercado-Silva, N. (2005) Condition index of the eastern oyster, Crassostrea virginica (Gmelin, 1791) in Sapelo Island Georgia—effects of site, position on bed and pea crab parasitism. Journal of Shellfish Research 24, 121–126.Google Scholar
Minchin, D. (2003) Introductions: some biological and ecological characteristics of scallops. Aquatic Living Resources 16, 521–532.CrossRefGoogle Scholar
Mladineo, I. and Peharda, M. (2009) Histopathology of Gymnophallus sp. sporocysts in the edible mytilid, Modiolus barbatus. Journal of Shellfish Research 24, 1097–1100.Google Scholar
Mourgaud, Y., Martinez, É., Geffard, A., Andral, B., Stanisiere, J.Y. and Amiard, J.C. (2002) Metallothionein concentration in the mussel Mytilus galloprovincialis as a biomarker of response to metal contamination: validation in the field. Biomarkers 7, 479–490.CrossRefGoogle ScholarPubMed
Navas, J.I., Castillo, M.C., Vera, P. and Ruiz-Rico, M. (1992) Principal parasites observed in clams, Ruditapes decussatus (L.), Ruditapes philippinarum (Adams et Reeve), Venerupis pullastra (Montagu) and Venerupis aureus (Gmelin), from the Huelva coast (S.W. Spain). Aquaculture 107, 193–199.CrossRefGoogle Scholar
Nicoll, W. (1906) Notes on trematode parasites of the cockle (Cardium edule) and mussel (Mytilus edulis). Annals and Magazine of Natural History (Series 7) 17, 147–155.CrossRefGoogle Scholar
Novoa, B., Posada, D. and Figueras, A. (2005) Polymorphisms in the sequences of Marteilia internal transcribed spacer region of the ribosomal RNA genes (ITS-1) in Spain: genetic types are not related with bivalve hosts. Journal of Fish Diseases 28, 331–338.CrossRefGoogle Scholar
Nowak, B.F. and LaPatra, S.E. (2006) Epitheliocystis in fish. Journal of Fish Diseases 29, 573–588.CrossRefGoogle ScholarPubMed
O'Beirn, F.X. and Walker, R.L. (1999) Pea crab, Pinnotheres ostreum Say, 1817, in the eastern oyster, Crassostrea virginica (Gmelin, 1791): prevalence and apparent adverse effects on oyster gonad development. Veliger 42, 17–20.Google Scholar
Ordás, M.C. and Figueras, A. (2005) Histopathological study of abnormal mortalities of cockle (Cerastoderma edule) in Carril (Galicia, NW Spain). Bulletin of the European Association of Fish Pathologists 25, 124–130.Google Scholar
Overstreet, R.M. and Curran, S.S. (2002) Superfamily Bucephaloidea Poche, 1907. In Gibson, D.I., Jones, A. and Bray, R.A. (eds) Keys to the Trematoda. Wallingford, UK: CABI, pp. 67–110.CrossRefGoogle Scholar
Paillard, C. (2004) A short-review of brown ring disease, a vibriosis affecting clams, Ruditapes philippinarum and Ruditapes decussatus. Aquatic Living Resources 17, 467–475.CrossRefGoogle Scholar
Paillard, C., Maes, P. and Oubella, R. (1994) Brown ring disease in clams. Annual Review of Fish Diseases 4, 219–240.CrossRefGoogle Scholar
Palombi, A. (1930) Il ciclo biologico di Diphtherostomum brusinae Stossich (Trematode digenetico: fam. Zoogonidae Odhner). Considerazioni sui cicli evolutivi delle specie affini e dei trematodi in generale. Pubblicazioni della Stazione Zoologica di Napoli 10, 111–150.Google Scholar
Park, K.I., Tsutsumi, H., Hong, J.S. and Choi, K.S. (2008) Pathology survey of the short-neck clam Ruditapes philippinarum occurring on sandy tidal flats along the coast of Ariake Bay, Kyushu, Japan. Journal of Invertebrate Pathology 99, 212–219.CrossRefGoogle Scholar
Paul-Pont, I., Gonzalez, P., Baudrimont, M., Jude, F., Raymond, N., Bourrasseau, L., Le Goïc, N., Haynes, F., Legeay, A., Paillard, C. and de Montaudouin, X. (2010) Interactive effects of metal contamination and pathogenic organisms on the marine bivalve Cerastoderma edule. Marine Pollution Bulletin 60, 515–525.CrossRefGoogle ScholarPubMed
Pekkarinen, M. and Ching, H.L. (1994) Comparisons of gymnophallid digeneans from North Pacific and Baltic clams, Macoma balthica (Bivalvia). Journal of Parasitology 80, 630–636.CrossRefGoogle ScholarPubMed
Pelseneer, P. (1906) Trematodes parasites de mollusques marins. Bulletin Scientifique de la France et de la Belgique 40, 161–186.Google Scholar
Pike, A.W. and Burt, M.D.B. (1981) Paravortex karlingi sp. nov. from Cerastoderma edule L., in Britain. Hydrobiologia 84, 23–30.CrossRefGoogle Scholar
Pina, S., Barandela, T., Santos, M.J., Russell-Pinto, F. and Rodrigues, P. (2009a) Identification and description of Bucephalus minimus (Digenea: Bucephalidae) life cycle in Portugal: morphological, histopathological, and molecular data. Journal of Parasitology 95, 353–359.CrossRefGoogle ScholarPubMed
Pina, S., Tajdari, J., Russell-Pinto, F. and Rodrigues, P. (2009b) Morphological and molecular studies on life cycle stages of Diphtherostomum brusinae (Digenea: Zoogonidae) from northern Portugal. Journal of Helminthology 83, 321–331.CrossRefGoogle ScholarPubMed
Poder, M. and Auffret, M. (1986) Sarcomatous lesion in the cockle Cerastoderma edule: I. Morphology and population survey in Brittany, France. Aquaculture 58, 1–8.CrossRefGoogle Scholar
Príncep, M., Bigas, M. and Durfort, M. (1996) Incidence of Bucephallus haimeanus (Lacaze-Duthiers, 1854) (Trematoda, Digenea) in the digestive gland of Ostrea edulis Linné. Iberus 14, 211–220.Google Scholar
Príncep, M. and Durfort, M. (1993) Estudio ultraestructural de las fases larvarias de Bucephallus haimeanus (Trematoda, Digenea) halladas en el primer huésped intermediario Ostrea edulis L. Miscellaneous Zoology 17, 35–48.Google Scholar
Reimer, L.W. (1973) Das auftreten eines fischtrematoden der gattung Asymphylodora Looss, 1899, bei Nereis diversicolor O.F. Müller als beispiel für einen alternativzyklus. Zoologischer Anzeiger 191, 187–196.Google Scholar
Reise, K. (2003) Metapopulation structure in the lagoon cockle Cerastoderma lamarcki in the northern Wadden Sea. Helgoland Marine Research 56, 252–258.CrossRefGoogle Scholar
Romalde, J.L., Vilariño, M.L., Beaz, R., Rodriguez, J.M., Diaz, S., Villalba, A. and Carballal, M.J. (2007) Evidence of retroviral etiology for disseminated neoplasia in cockles (Cerastoderma edule). Journal of Invertebrate Pathology 94, 95–101.CrossRefGoogle ScholarPubMed
Russell-Pinto, F., Gonçalves, J.F. and Bowers, E. (2006) Digenean larvae parasitizing Cerastoderma edule (Bivalvia) and Nassarius reticulatus (Gastropoda) from Ria de Aveiro, Portugal. Journal of Parasitology 92, 319–332.CrossRefGoogle ScholarPubMed
Sannia, A. and James, B.L. (1978) The occurrence of Cercaria cerastodermae I Sannia, James, and Bowers, 1978 (Digenea: Monorchiidae) in populations of Cerastoderma edule (L.) from the commercial beds of the Lower Thames Estuary. Parasitology Research 56, 1–11.Google Scholar
Scholz, T. (2002) Family Gymnophallidae Odhner, 1905. In Gibson, D.I., Jones, A. and Bray, R.A. (eds) Keys to the Trematoda. Wallingford, UK: CABI, pp. 245–251.CrossRefGoogle Scholar
Soto, M., Pascual, S., Rodriguez, H., Gestal, C., Abollo, E., Arias, C. and Estévez, J. (1996) Nematopsis spp. Schneider, 1892 (Apicomplexa: Gregarinida) in bivalve molluscs off Ria de Vigo (Galicia, NW Spain). Bulletin of the European Association of Fish Pathologists 16, 157–160.Google Scholar
Stock, J.H. (1993) Copepoda (Crustacea) associated with commercial and non-commercial Bivalvia in the East Scheldt, The Netherlands. Bijdragen tot de Dierkunde 63, 61–64.CrossRefGoogle Scholar
Stossich, M. (1887) Brani di elmintologia tergestina, IV. Bollettino della Società Adriatica di Scienz Naturali in Trieste 10, 90–96.Google Scholar
Stunkard, H.W. (1938) The morphology and life cycle of the trematode Himasthla quissetensis (Miller and Northup, 1926). Biological Bulletin. Marine Biological laboratory, Woods Hole 75, 145–164.CrossRefGoogle Scholar
Stunkard, H.W. and Uzmann, J.R. (1958) Studies on digenetic trematodes of the genera Gymnophallus and Parvatrema. Biological Bulletin. Marine Biological Laboratory, Woods Hole 115, 276–302.CrossRefGoogle Scholar
Subida, M.D., Arias, A.M., Drake, P., Garcia-Raso, J.E., Rodriguez, A., and Cuesta, J.A. (2011) On the occurrence of Afropinnotheres monodi Manning, 1993 (Decapoda: Pinnotheridae) in European waters. Journal of Crustacean Biology 31, 367–369.CrossRefGoogle Scholar
Sun, J. and Wu, X. (2004) Histology, ultrastructure, and morphogenesis of a Rickettsia-like organism causing disease in the oyster, Crassostrea ariakensis Gould. Journal of Invertebrate Pathology 86, 77–86.CrossRefGoogle ScholarPubMed
Sun, W., Sun, S., Yuqi, W., Baowen, Y. and Weibo, S. (2006) The prevalence of the pea crab, Pinnotheres sinensis, and its impact on the condition of the cultured mussel, Mytilus galloprovincialis, in Jiaonan waters (Shandong Province, China). Aquaculture 253, 57–63.CrossRefGoogle Scholar
Tennent, D.H. (1906) A study of the life-history of Bucephalus haimeanus; a parasite of the oyster. Journal of Cell Science s2-49, 635–690.CrossRefGoogle Scholar
Thébault, A., Bergman, S., Pouillot, R., Le Roux, F. and Berthe, F.C.J. (2005) Validation of in situ hybridisation and histology assays for the detection of the oyster parasite Marteilia refringens. Diseases of Aquatic Organisms 65, 9–16.CrossRefGoogle ScholarPubMed
Thieltges, D.W. (2006) Parasite induced summer mortality in the cockle Cerastoderma edule by the trematode Gymnophallus choledochus. Hydrobiologia 559, 455–461.CrossRefGoogle Scholar
Thieltges, D.W. (2007) Habitat and transmission—effect of tidal level and upstream host density on metacercarial load in an intertidal bivalve. Parasitology 134, 599–605.CrossRefGoogle Scholar
Thieltges, D.W. (2008) Effect of host size and temporal exposure on metacercarial infection levels in the intertidal cockle Cerastoderma edule. Journal of the Marine Biological Association of the United Kingdom 88, 613–616.CrossRefGoogle Scholar
Thieltges, D.W., Hussell, B., Hermann, J., Jensen, K.T., Krakau, M., Taraschewski, H. and Reise, K. (2008) Parasites in the northern Wadden Sea: a conservative ecosystem component over 4 decades. Helgoland Marine Research 62, 37–47.CrossRefGoogle Scholar
Thieltges, D.W., Krakau, M., Andresen, H., Fottner, S. and Reise, K. (2006) Macroparasite community in molluscs of a tidal basin in the Wadden Sea. Helgoland Marine Research 60, 307–316.CrossRefGoogle Scholar
Thieltges, D.W. and Reise, K. (2006) Metazoan parasites in intertidal cockles Cerastoderma edule from the northern Wadden Sea. Journal of Sea Research 56, 284–293.CrossRefGoogle Scholar
Thieltges, D.W. and Reise, K. (2007) Spatial heterogeneity in parasite infections at different spatial scales in an intertidal bivalve. Oecologia 150, 569–581.CrossRefGoogle Scholar
Thieltges, D.W. and Rick, J. (2006) Effect of temperature on emergence, survival and infectivity of cercariae of the marine trematode Renicola roscovita (Digenea: Renicolidae). Diseases of Aquatic Organisms 73, 63–68.Google ScholarPubMed
Twomey, E. and Mulcahy, M.F. (1988) Epizootiological aspects of a sarcoma in the cockle Cerastoderma edule. Diseases of Aquatic Organisms 5, 225–238.CrossRefGoogle Scholar
van Banning, P. (1979) Protistan parasites observed in the European flat oyster (Ostrea edulis) and the cockle (Cerastoderma edule) from some coastal areas of the Netherlands. Haliotis 8, 33–37.Google Scholar
Vaullegeard, A. (1900) Etude expérimenatle et critique sur l'action des helminthes: I. Cestodes et nématodes. Bulletin de la Société Linnéene de Normandie 5, 84–142.Google Scholar
Villalba, A., Carballal, M.J. and López, C. (2001) Disseminated neoplasia and large foci indicating heavy haemocytic infiltration in cockles Cerastoderma edule from Galicia (NW Spain). Diseases of Aquatic Organisms 46, 213–216.CrossRefGoogle ScholarPubMed
Watermann, B., Thomsen, A., Kolodzey, H., Daehne, B., Meemken, M., Pijanowska, U. and Liebezeit, G. (2008) Histopathological lesions of molluscs in the harbour of Norderney, Lower Saxony, North Sea (Germany). Helgoland Marine Research 62, 167–175.CrossRefGoogle Scholar
Wegeberg, A.M., de Montaudouin, X. and Jensen, K.T. (1999) Effect of intermediate host size (Cerastoderma edule) on infectivity of cercariae of three Himasthla species (Echinostomatidae, Trematoda). Journal of Experimental Marine Biology and Ecology 238, 259–269.CrossRefGoogle Scholar
Wegeberg, A.M. and Jensen, K.T. (1999) Reduced survivorship of Himasthla (Trematoda, Digenea)-infected cockles (Cerastoderma edule) exposed to oxygen depletion. Journal of Sea Research 42, 325–331.CrossRefGoogle Scholar
Wegeberg, A.M. and Jensen, K.T. (2003) In situ growth of juvenile cockles, Cerastoderma edule, experimentally infected with larval trematodes (Himasthla interrupta). Journal of Sea Research 50, 37–43.CrossRefGoogle Scholar
Zander, C.D. (1998) Ecology of host parasite relationships in the Baltic Sea. Naturwissenschaften 85, 426–436.CrossRefGoogle ScholarPubMed
Zander, C.D. and Reimer, L.W. (2002) Parasitism at the ecosystem level in the Baltic Sea. Parasitology 124, S119–S135.CrossRefGoogle ScholarPubMed