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Apatite Growth on Bioactive Glass in Artificial Saliva

Published online by Cambridge University Press:  15 March 2011

Sarah E. Efflandt ,
Robert F. Cook  and
Lorraine F. Francis
Sarah E. Efflandt
Affiliation:
Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, U.S.A.
Robert F. Cook
Affiliation:
Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, U.S.A.
Lorraine F. Francis
Affiliation:
Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, U.S.A.
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Abstract

Bioactive glass disks from the MgO-CaO-P2O5-SiO2 system were placed in artificial saliva for time periods varying from 1 to 42 days. Surfaces were then analyzed using scanning electron microscopy (SEM) and x-ray diffraction to investigate surface morphologies and crystallinity. SEM examination exhibited dramatic surface changes as early as 2 d. X-ray results showed crystallinity in the form of apatite at 10 d, which became more developed though 42 d. The bioactive glass in water and non-bioactive glass in artificial saliva were used as controls; both exhibited no evidence of apatite formation on their surfaces through the 42 d time period. This study shows that bioactive glass reacts in artificial saliva to form apatite and that the apatite layer becomes better crystallized over an extended time period. These results give a better understanding of the surface changes and mineralization that occur over time and can be used to interpret results from in vitro and in vivo studies done on bioactive glass in the oral environment.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 662: Symposia LL/MM/NN/OO – Biomaterials for Drug Delivery & Tissue Engineering , 2000 , LL2.5
Copyright
Copyright © Materials Research Society 2001

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References

1. Kokubo, T., Ito, S., Huang, Z., Hayashi, T., Sakka, S., Kitsugi, T., Yamamuro, T.. Ca, P-rich Layer formed on High-Strength Bioactive Glass-Ceramic AW. J Biomed Mater Res 24: 331–343 (1990).Google Scholar
2. Hench, L.L., Splinter, R.J., Allen, W.C., Greenlee, T.K.. Bonding Mechanisms at the Interface of Ceramic Prosthetic Materials. J Biomed Mater Res Symposium 2: 117–141 (1971).Google Scholar
3. Takata, T., Katauchi, K., Akagawa, Y., Nikai, H.. New Connective Tissue Attachment formation on various Biomaterials Implanted in Roots. Int J Oral & Maxillofac Implants 9: 77–84 (1994).Google Scholar
4. Cook, S., Dalton, J.. Biocompatibility and Biofunctionality of Implanted Materials. Alpha Omegan 85: 41–47 (1992).Google Scholar
5. Kudo, K., Miyasawa, M., Fujioka, Y., Kamegai, T., Nakano, H., Seino, Y., Ishikawa, F., Shioyama, T., Ishibashi, K.. Clinical application of Dental Implant with Root of Coated Bioglass: short-term results. Oral Surg Oral Med Oral Path 70: 18–23 (1990).Google Scholar
6. Efflandt, S.E., Magne, P., Douglas, W.H., Francis, L.F.. The Bonding of Bioactive Glasses to Human Dentin, Proceedings of the 11th International Symposium on Ceramics in Medicine, ed. LeGeros, R.Z. and LeGeros, J.P. (World Scientific, 1998) pp. 571–574.Google Scholar
7. Kokubo, T.. Surface Chemistry of Bioactive Glass-Ceramics. J Non-Crystalline Solids 120: 138–151 (1990).Google Scholar
8. Cate, A. Ten. Oral Histology: Development Structure and Function. St. Louis, MO: The C.V. Mosby Co. (1980).Google Scholar
9. Tantbirojn, D.. Laboratory Evaluation of a Fluoride-Containing Composite Resin. Masters Thesis, University of Alabama (1991) pp. 38.Google Scholar