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DNA Templating of Ethylene-Oxide-Coated Nanoclusters

Published online by Cambridge University Press:  11 February 2011

S. Jhaveri ,
E. E. Foos ,
M. G. Ancona ,
A. W. Snow ,
M. E. Twigg ,
E. Chang ,
K. Pilobello ,
E. Goldman  and
D. Lowy
S. Jhaveri
Affiliation:
NRC Postdoctoral Associate
E. E. Foos
Affiliation:
Naval Research Laboratory, Washington, DC 20375
M. G. Ancona
Affiliation:
Naval Research Laboratory, Washington, DC 20375
A. W. Snow
Affiliation:
Naval Research Laboratory, Washington, DC 20375
M. E. Twigg
Affiliation:
Naval Research Laboratory, Washington, DC 20375
E. Chang
Affiliation:
Naval Research Laboratory, Washington, DC 20375
K. Pilobello
Affiliation:
Nova Research, Alexandria, VA, E-mail: sulay@cbmse.nrl.navy.mil, foos@ccs.nrl.navy.mil
E. Goldman
Affiliation:
Naval Research Laboratory, Washington, DC 20375
D. Lowy
Affiliation:
Nova Research, Alexandria, VA, E-mail: sulay@cbmse.nrl.navy.mil, foos@ccs.nrl.navy.mil
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Abstract

Using gel electrophoresis we demonstrate the attachment of short ssDNAs to a new type of water-soluble gold nanocluster that is encapsulated with ethylene oxide ligands. Initial experiments indicate that these DNA/nanocluster conjugates can subsequently be hybridized to a longer DNA template suggesting a pathway for nanofabrication of multi-cluster assemblies.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 735: Symposium C – Bioinspired Nanoscale Hybrid Systems , 2002 , C11.41
Copyright
Copyright © Materials Research Society 2003

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References

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