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Dual Detection Platform with Refractive Index and SERS Sensing Based on Colloidal Gold Functionalized Porous Silicon Substrates

Published online by Cambridge University Press:  01 February 2011

Yang Jiao ,
Dmitry S. Koktysh  and
Sharon M. Weiss
Yang Jiao
Affiliation:
Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37235, U.S.A.
Dmitry S. Koktysh
Affiliation:
Department of Chemistry, Vanderbilt University, Nashville, TN 37235, U.S.A. Vanderbilt Institute of Nanoscale Science and Engineering, Vanderbilt University, Nashville, TN 37235, U.S.A.
Sharon M. Weiss*
Affiliation:
Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37235, U.S.A. Vanderbilt Institute of Nanoscale Science and Engineering, Vanderbilt University, Nashville, TN 37235, U.S.A.
*
a)Electronic mail: sharon.weiss@vanderbilt.edu
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Abstract

We demonstrate a dual-mode sensing platform based on porous silicon (PSi) substrates coated with colloidal gold (Au) nanoparticles (NPs). This Au-PSi composite structure supports both molecular fingerprinting via surface enhanced Raman scattering (SERS) and quantification of molecular binding via reflectance measurements. Reflectance shifts of 7-10 nm in the infrared region were observed in the case of adsorbing benzenethiol or antioxidant glutathione molecules on the surface of Au NPs. Subsequent SERS measurements showed unique identification for both molecules and provided a < 1 μM and < 1 mM detection resolution for benzenethiol and glutathione, respectively.

Keywords

sensorRaman spectroscopynanoscale
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1301: Symposium V/NN/OO/PP – Soft Matter, Biological Materials and Biomedical Materials—Synthesis, Characterization and Applications , 2011 , mrsf10-1301-pp08-06
Copyright
Copyright © Materials Research Society 2011

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References

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