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Formation of Two-Dimensional Crystals of Membrane-Anchored and Water-Soluble Proteins

Published online by Cambridge University Press:  15 February 2011

Harald Engelhardt ,
T. Scheybani ,
W. Von Gustedt  and
W. Baumeister
Harald Engelhardt
Affiliation:
Max-Planck-Institut für Biochemie, D-82152 Martinsried, Germany
T. Scheybani
Affiliation:
Max-Planck-Institut für Biochemie, D-82152 Martinsried, Germany
W. Von Gustedt
Affiliation:
Max-Planck-Institut für Biochemie, D-82152 Martinsried, Germany
W. Baumeister
Affiliation:
Max-Planck-Institut für Biochemie, D-82152 Martinsried, Germany
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Abstract

The formation of two-dimensional (2-D) crystals of biological macromolecules is of interest for nanotechnological applications. Protein 2-D crystals may be used as molecular sieves and/or support devices as components of biosensors etc. [1]. Functionally specialized 2-D crystals, containing transport or catalytic proteins, provide a certain function in a highly efficient and vectorial manner. Future developments may allow the design of more complex structures such as multilayers made from different proteins or arrays of functionally linked oligo- or multimeric complexes consisting of multiple protein species [2]. Regular 2-D arrays, either truely crystalline or densely packed molecules, are one of the basic structures taht might be used to construct more sophisticated protein-based devices. 2-D crystals have some interesting features:

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 330: Symposium S – Biomolecular Materials by Design , 1993 , 201
Copyright
Copyright © Materials Research Society 1994

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References

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