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Detection of Protein by Reduced Graphene Oxide Field-Effect Transistor

Published online by Cambridge University Press:  11 April 2014

Masaki Hasegawa ,
Yuki Hirayama ,
Yasuhide Ohno ,
Kenzo Maehashi  and
Kazuhiko Matsumoto
Masaki Hasegawa
Affiliation:
Merck Ltd., Japan, 4084 Nakatsu, Aikawa, Aiko, Kanagawa 243-0303, Japan
Yuki Hirayama
Affiliation:
Merck Ltd., Japan, 4084 Nakatsu, Aikawa, Aiko, Kanagawa 243-0303, Japan
Yasuhide Ohno
Affiliation:
The Institute of the Science and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
Kenzo Maehashi
Affiliation:
The Institute of the Science and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
Kazuhiko Matsumoto
Affiliation:
The Institute of the Science and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
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Abstract

We confirmed a specific detection of immunoglobulin E(IgE) by using an aptamer immobilized reduced graphene oxide(rGo) field effect transistor(FET). A detection limit and dynamic range were estimated 8.1 ng/ml and 10000 respectively. These characteristics are comparable with current fluorescent markers. Although a mobility of rGo FET was around 5 cm2/V.sec, and this is two to three orders lower than mechanically exfoliated pristine graphene FET, a sensitivity of it was only one order lower than using pristine graphene.

Keywords

Cbiologicalsensor
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1586: Symposium C – Advanced Nano Carbon Devices and Materials , 2014 , jsapmrs13-1586-6467
Copyright
Copyright © Materials Research Society 2014 

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References

REFERENCES

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