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Changes in the surface of Dipetalonema viteae (Filarioidea) during its development as shown by comparative peptide mapping

Published online by Cambridge University Press:  06 April 2009

Werner Baschong
Werner Baschong
Affiliation:
Swiss Tropical Institute, Socinstrasse 57, CH-4051 Basel, Switzerland
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Extract

The cuticle of parasitic nematodes, the main contact site with the host, plays an important role in host-parasite interaction and thus also in immunological control. We compared different surface-iodinated life-stages of the filarial worm Dipetalonema viteae (microfilariae, infective 3rd-stage larvae (L3), adult males and females) with respect to changes in their surface composition. Autoradiographs of peptide maps show that all stages present an identical set of peptide spots reflecting common surface protein(s). Spots specific for larvae L3 show that the composition of the iodinated surface differs in microfilariae and adults i.e. it changes during development. Adults show a spot typical for males or females. Identical spots are found in L3. This suggests that a surface component is also sex specific.

Type
Research Article
Information
Parasitology , Volume 90 , Issue 2 , April 1985 , pp. 351 - 356
Copyright
Copyright © Cambridge University Press 1985

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