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A note on the effects of antimalarial drugs on the sporogonous cycle of Plasmodium cynomolgi in Anopheles stephensi*

Published online by Cambridge University Press:  06 April 2009

Levon A. Terzian
Levon A. Terzian
Affiliation:
Naval Medical Research Institute, Bethesda, Maryland 20014
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Extract

It has been shown that in common with other malarial species the drug response in the sporogonous cycle of Plasmodium cynomolgi parallels in a special way the drug response in the schizogonous cycle. Thus, prophylactic drugs produce deteriorating changes in the oocysts while curative drugs have a destructive effect on the sporozoites. A comparison of the effects of prophylactic drugs on the sporogonous and schizogonous cycles of the four malarial species studied thus far suggests the presence of more than one pre-erythrocytic developmental stage in the schizogonous cycles of P. vivax and P. cynomolgi following the initial invasion by the sporozoite.

Type
Research Article
Information
Parasitology , Volume 61 , Issue 2 , October 1970 , pp. 191 - 194
Copyright
Copyright © Cambridge University Press 1970

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References

REFERENCES

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