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Crystal and X-ray powder diffraction data for cefotaxime sodium salt, C16H16N5NaO7S2

Published online by Cambridge University Press:  10 January 2013

Héctor Novoa de Armas ,
Eladio Pardillo-Fontdevila  and
Ramón Pomés Hernández
Héctor Novoa de Armas*
Affiliation:
Center of Pharmaceutical Chemistry, P.O. Box 16042, Havana, Cuba
Eladio Pardillo-Fontdevila
Affiliation:
Center of Pharmaceutical Chemistry, P.O. Box 16042, Havana, Cuba
Ramón Pomés Hernández
Affiliation:
National Center for Scientific Research, P.O. Box 6990, Havana, Cuba
*
a)Author to whom correspondence should be addressed. Present address: Laboratorium voor Analytische Chemie en Medicinale Fysicochemie. Katholieke Universiteit Leuven (KUL). Van Evenstraat 4, 3000 Leuven, Belgium. E-mail: hector.novoa@farm.kuleuven.ac.be
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Abstract

An indexed powder diffraction pattern and related crystallographic data are reported for cefotaxime sodium salt: 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2amino-4-thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo, monosodium salt, [6R−[6α,7β(Z)]], C16H16N5NaO7S2. The unit cell dimensions were determined from diffractometer methods, using monochromatic CuKα1 radiation, and evaluated by indexing programs. The monoclinic cell found for cefotaxime sodium was a=13.063(2) Å, b=8.916(2) Å, c=9.726(2) Å, β=107.34(2)°, Z=2, space groups: P21 (No. 4) or P21/m (No. 11), Dx=1.467 g/cm3.

Type
Research Article
Information
Powder Diffraction , Volume 14 , Issue 2 , June 1999 , pp. 142 - 144
Copyright
Copyright © Cambridge University Press 1999

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