We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Boren, J, Rustaeus, S & Olofsson, S-O (1994) Studies on the assembly of apolipoprotein B-100 and B-48 containing very low density lipoproteins in McA-RH7777 cells. Journal of Biological Chemistry269, 25879–25888.Google Scholar
Boren, J, Rustaeus, S, Wettesten, M, Andersson, M, Wiklund, A & Olofsson, S-O (1993) Influence of triacylglycerol biosynthetic rate on the assembly of apo-B100 containing lipoproteins in Hep-G2 cells. Arteriosclerosis and Thrombosis13, 1743–1754.CrossRefGoogle Scholar
Boren, J, Wettesten, M, Sjoberg, A, Thorlin, T, Bondjer, G, Wilklund, O, Carlsson, P & Olofsson, S-O (1990) Studies on the assembly of apo-B100 containing lipoproteins in HepG2 cells. Journal of Biological Chemistry263, 4434–4442.Google Scholar
Cartwright, IJ, Hebbachi, A-M & Higgins, JA (1993) Transit and sorting of apolipoprotein B within the endoplasmic reticulum and Golgi compartments of isolated hepatocytes from normal and orotic acid fed rats. Journal of Biological Chemistry268, 20937–20952.CrossRefGoogle ScholarPubMed
Cartwright, IJ & Higgins, JA (1992) Quantification of apolipoprotein B-48 and B-100 in rat liver endoplasmic reticulum and Golgi. Biochemical Journal285, 153–159.Google Scholar
Cartwright, IJ & Higgins, JA (1995) Intracellular events in the assembly of very low density lipoprotein lipids with apolipo protein B in isolated rabbit hepatocytes. Biochemical Journal310, 897–907.Google Scholar
Cartwright, IJ & Higgins, JA (1996) Intracellular degradation in the regulation of secretion of apolipoprotein B-100 by rabbit hepatocytes. Biochemical Journal314, 377–384.Google Scholar
Cartwright, IJ, Higgins, JA, Wilkinson, J, Bellavia, S, Kendrick, JS & Graham, JM (1997) Investigation of the role of lipids in the assembly of very low density lipoproteins in rabbit hepatocytes. Journal of Lipid Research38, 531–545.Google Scholar
Davis, RA, Thrift, RN, Wu, CC & Howell, KE (1990) Apolipoprotein B is both integrated and translocated across the endoplasmic reticulum membrane. Journal of Biological Chemistry26, 10006–10011.Google Scholar
Dixon, JL, Furukawa, S & Ginsberg, HN (1991) Oleate stimulates secretion of apolipoprotein-B containing lipoproteins from Hep-G2 cells by inhibiting early intracellular degradation of apolipoprotein B. Journal of Biological Chemistry266, 5080–5086.CrossRefGoogle ScholarPubMed
Dixon, JL & Ginsberg, HN (1993) Regulation of hepatic secretion of apolipoprotein B containing lipoproteins; information obtained from cultured liver cells. Journal of Lipid Research34, 167–179.Google Scholar
Du, EZ, Kurth, J, Wang, S-L, Humiston, P & Davis, RA (1994) Proteolysis coupled secretion of the N terminus of apolipoprotein-B. Journal of Biological Chemistry269, 4169–4176.Google Scholar
Gibbons, GF (1994) A comparison of in vitro models to study hepatic lipid and lipoprotein metabolism. Current Opinion in Lipidology5, 191–198.Google Scholar
Gordon, DA, Jamit, H, Gregg, RE, Olofsson, S-O & Boren, J (1996) Inhibition of the microsomal triglyceride transfer step blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of the core lipids in the second step. Journal of Biological Chemistry271, 33047–33053.Google Scholar
Gordon, DA, Wetterau, JR & Gregg, RE (1995) Microsomal triglyceride transfer protein: a protein complex required for the assembly of lipoprotein particles. Trends in Cell Biology5, 317–332.Google Scholar
Higgins, JA & Hutson, JL (1984) The roles of Golgi and endoplasmic reticulum in the synthesis and assembly of lipoprotein lipids in rat hepatocytes. Journal of Lipid Research25, 1295–1305.Google Scholar
Jamil, H, Dickson, JE, Ching-Hsuen, C, Lago, MW, Rinhhaert, JK, Biller, SA, Gregg, RE & Wetterau, JR (1995) Microsomal triglyceride transfer protein: specificity of lipid binding and transport. Journal of Biological Chemistry270, 6549–6554.Google Scholar
Kosykh, VA, Surguchov, AP, Podres, EA, Novikov, DK & Sudarickoc, (1988) VLDL apoprotein secretion and apo-B mRNA levels in primary culture of cholesterol loaded rabbit hepatocytes. FEBS Letters232, 103–106.Google Scholar
Lang, CA & Davis, RA (1990) Fish oil fatty acids impair VLDL assembly and/or secretion by cultured rat hepatocytes. Journal of Lipid Research31, 2079–2086.Google Scholar
Packard, CJ, Munro, A, Lorimer, AR, Gotto, AM & Shepherd, J (1984) Metabolism of apolipoprotein B in large triglyceride rich very low density lipoproteins of normal and hypertriglyceridaemic subjects. Journal of Clinical Investigation74, 2178–2192.Google Scholar
Pullinger, CR, North, JD, Teng, B-B, Rifici, VA, Ronhild de Brito, AE & Scott, J (1989) Apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin and insulin and measurement of the mRNA half life. Journal of Lipid Research30, 1065–1077.Google Scholar
Sato, R, Imanaka, T, Takatsuki, A & Takano, T (1990) Degradation of newly synthesized apolipoprotein B by rat hepatocytes. Journal of Biological Chemistry265, 11880–11884.Google Scholar
Shepherd, J & Packard, CJ (1987) Metabolic heterogeneity in very low density lipoproteins. American Heart Journal113, 503–508.Google Scholar
Sniderman, AD & Cianflone, K (1993) Substrate delivery as a determinant of hepatic apo-B secretion. Arteriosclerosis and Thombosis13, 629–636.Google Scholar
Wang, H, Chen, X & Fisher, EA (1993) n-3 Fatty acids stimulate intracellular degradation of apolipoprotein B in rat hepatocytes. Journal of Clinical Investigation91, 1380–1389.Google Scholar
White, AL, Graham, DL, LeGros, J, Pease, RJ & Scott, J (1992) Oleate mediated stimulation of apolipoprotein B secretion from rat hepatoma cells. Journal of Biological Chemistry267, 15657–15664.Google Scholar
Wilkinson, J, Higgins, JA, Groot, PHE, Gherardi, E & Bowyer, DE (1992) Determination of the intracellular distribution and pool sizes of apolipoprotein B in rabbit liver. Biochemical Journal288, 413–419.Google Scholar
Wilkinson, J, Higgins, JA, Groot, PHE, Gherardi, E & Bowyer, DE (1993) Topography of apolipoprotein B in subcellular fractions of rabbit liver probed with a panel of monoclonal antibodies. Journal of Lipid Research34, 815–825.Google Scholar
Wu, X, Zhou, M, Huang, L-S, Wetterau, J & Ginsberg, HN (1996) Demonstration of a physical interaction between microsomal triglyceride transfer protein and apolipoprotein B during the assembly of apo-B containing lipoproteins. Journal of Biological Chemistry271, 10277–10281.Google Scholar
Yeung, SJ, Chen, SH & Chan, L (1996) Ubiquitin proteosome pathway mediates intracellular degradation of apolipoprotein B. Biochemistry35, 13843–13848.Google Scholar
Zhou, M, Wu, X, Huang, L-S & Ginsberg, HN (1995) Apolipoprotein B 100, an inefficiently translocated secretory protein is bound to the cytosolic chaperone heat shock protein 70. Journal of Biological Chemistry270, 25220–25224.Google Scholar