Hostname: page-component-84b7d79bbc-g78kv Total loading time: 0 Render date: 2024-07-27T23:26:50.219Z Has data issue: false hasContentIssue false
  • English
  • Français

Antihypertensive drugs and depression: a reappraisal

Published online by Cambridge University Press:  09 July 2009

Wendy P. Bant
Wendy P. Bant*
Affiliation:
Middlewood Hospital, Sheffield
*
1Address for correspondence: Dr Wendy P. Bant, Middlewood Hospital, Sheffield.
Get access Rights & Permissions [Opens in a new window]

Synopsis

Eighty-nine new referral hypertensive out-patients and 46 new referral non-hypertensive chronically physically ill out-patients completed a mood rating scale at regular intervals for one year. The results showed a high prevalence of depression in both groups of patients, with no preponderance in the hypertensive group. Hypertensive patients with psychiatric histories had a higher prevalence of depression than the comparison patients. This was accounted for by a significant number of depressions occurring in methyl dopa treated patients with psychiatric histories.

Type
Research Article
Information
Psychological Medicine , Volume 8 , Issue 2 , May 1978 , pp. 275 - 283
Copyright
Copyright © Cambridge University Press 1978

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abrahams, R. C., Kanter, V. B., Rosen, I. & Standen, J. L. (1963). A controlled clinical trial of imipramine with outpatients. British Journal of Psychiatry 109, 286–292.CrossRefGoogle Scholar
Achor, R. W. P., Hanson, N. O. & Gifford, R. W. (1955). Hypertension treated with Rauwolfia Serpentia, and with reserpine. Journal of American Medical Association 159, 841–845.CrossRefGoogle Scholar
Briant, R. H., Reid, J. L. & Dollery, C. T. (1973). Interaction between clonidine and desipramine in man. British Medical Journal i, 522–523.CrossRefGoogle Scholar
Bulpitt, C. J. & Dollery, C. T. (1973). Side effects of hypotensive agents evaluated by a self-administered questionnaire. British Medical Journal iii, 485–490.CrossRefGoogle Scholar
Dollery, C. T. & Harrington, M. (1962). Methyl dopa in hypertension – clinical and pharmacological studies. Lancet i, 759–763.Google Scholar
Faucett, R. L., Litin, E. M. & Achor, R. W. P. (1957). Neuropharmacologc action of Rauwolfia compounds and its psychodynamic implication. Archives of Neurology and Psychiatry 77, 573–578.CrossRefGoogle Scholar
Freis, E. D. (1954). Mental depression in hypertensive patients treated for long periods with large doses of reserpine. New England Journal of Medicine 251, 1006–1008.CrossRefGoogle ScholarPubMed
Hamilton, M. & Kopelman, M. (1963). Treatment of severe hypertension with methyl dopa. British Medical Journal i, 151–155.CrossRefGoogle Scholar
Kanter, B. V. B. & Standen, D. C. (1961). British Hospital Progress Test. Cyclostyled report.Google Scholar
Leishman, A. W. D., Matthews, H. L. & Smith, A. J. (1963). Antagonism of guanethidine by imipramine. Lancet i, 112.CrossRefGoogle Scholar
Limieux, G., Davignon, A. & Genest, J. (1956). Depressive states during Rauwolfia therapy for arterial hypertension. Canadian Medical Association Journal 74, 522–526.Google Scholar
Mindham, R. H. S., Marsden, C. D. & Parkes, J. D. (1976). Psychiatric symptoms during L-dopa therapy for Parkinsons' disease. Psychological Medicine 6, 23–33.CrossRefGoogle Scholar
Muller, J. C., Pryor, W. W., Gibbons, J. E., Orgain, E. S. & Durham, N. C. (1955). Depression and anxiety occurring during Rauwolfia therapy. Journal of the American Medical Association 159, 836–840.Google Scholar
Sarwer-Foner, G. J., Sanders, S., Gomez, E. & Amadeo, M. (1966). A revalidation of a depression rating instrument – the British Hospital Progress Test. In On the Therapies of Depressive Illnesses. Canadian Psychiatric Association Journal, Vol. 2, Special Supplement, 92.Google Scholar
Schwarz, D., Michel, D. & Strian, F. (1973). Depressive Reaktionen unter antihypertensiver Behandlung. Archiv fur Psychiatrie und Nervenkrankheiten 218, 41–50.CrossRefGoogle Scholar
Snaith, R. P. & McCoubrie, M. (1974). Antihypertensive drugs and depression. Psychological Medicine 4, 393–398.CrossRefGoogle ScholarPubMed