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Beyond Nature and Culture: A Note on Medicine in the Age of Molecular Biology

Published online by Cambridge University Press:  26 September 2008

Hans-Jörg Rheinberger
Affiliation:
Institute for Genetics and General Biology, University of Salzburg

Abstract

The paper is divided into the two parts. In the first, I examine the relations among molecular biology, gene technology, and medicine as some aspect of the consequences of these relations with respect to the human genome project of the consequences of these relations with respect to the human genome project. I argue that the prevailing momentum of early molecular biology resided in argue that the prevailing momentum of relay molecular biology resided in crating the technical means for an extracellular representation of intracellular configurations. Assuch, its medical impact was rather limited. With the advent of recombinant DNA technology is based on the prospects of an intracellular representation of extracellular projects—the “rewriting” of life. Its medical impact is potentially unlimited. In the second part, I question the very opposition between nature and culture that implicitly underlies the notion of medicine as a “cultural system.” I argue that both on a macroscopic level (global ecological changes) and on a microscopic level (genetic engineering), the “natural” and the “social” are no longer to be seen as ontologically different.

In its uncanny oscillation between retrospection and foresight, between description and proclamation, and between assertion and hesitation, this essay translates an uneasiness that I have not been able to overcome while writing it. The essay conveys the tangled views of a hybrid author who himself cannot but oscillate between the perspectives of an actor in the field of molecular biology, a participant in the field of science studies, and a citizen

Type
Article
Copyright
Copyright © Cambridge University Press 1995

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References

Burke, D. T., Carle, G. F., and Maynard, VOlson. 1987. “Cloning of Large segments of Exogenous DNA into yeast by means of Artifical Choromosome Vectors. "Science: 806–12.Google Scholar
Cantor, Charles. 1992The Challenges of Technology and Informatics. “In kevels and Hood 1992, 98111.Google Scholar
Caskey, Thomas C. 1992. “DNA–Based Medicine: prevention and THerapy. "In kevles and Hood 1992, 112–35.Google Scholar
Derrida, jacques. 1978. “structure, sign and play in the Discourse of the Human sciences.”In hisWriting and Difference, 278–93. Chicago: University of Chicago press.Google Scholar
Elkana, Yehuda. 1981. “a programmatic Attempt at an Anthropology of knowledge. “In Sciences and cultures, edited by Everett, Mendelsohn and Yehuda, Elkana, 176. Dordrecht: Reidel.Google Scholar
Gilbert, Walter. 1992. “A vision of the Grail”. In kelves and Hood 1992, 8397.Google Scholar
Hoagland, Mahlon. 1990. Toward the Habit of truth. New York: Norton.Google Scholar
Hood, Leroy. 1992. “Biology and Medicine in the Twenty–First Century”. In kevles and Hood 1992, 136–63.Google Scholar
Horvath, S. J., Firca, J. R., Hunkapiller, T, Mw, Hunkapiller, and Hood, L. 1987. “An Automated DNA synthetizer Employing Deoxynucleoside 3'phosphoramidites”. Methods in Enzymology. 154: 314–26.CrossRefGoogle Scholar
Judson, , Horace, F. 1992. “A History of the science and Technology behind GeneMapping and sequencing”. In kevels and Hood 1992. 3780.Google Scholar
kay, Lily E. 1992. “Life as Techonology: Representing, Intervening, and Molecularizing.” MIT–papers.Manuscript.Google Scholar
kay, Lily E. 1993. The Molecular vision of life. Oxford: Oxford University press.Google Scholar
kay, Lily E. 1994. “Wer schrieb das Buch des Lebens? In Objekte, Diffrenzen undkonjunkturen. edited by Michael, Hagner, Hans–Jörg, Rheinberger, and Bettina, Wahring–Schmit. 151. Berlin: Akademie Verlag.Google Scholar
Keller, Evelyn Fox. 1990. “Physics and the Emergence of Molecular Biology: A History of Connitive and political Synergy”. Journal of the History ofBilogy 23: 389409.Google ScholarPubMed
Keller, Evelyn Fox. 1992. “Nature, and the Human Genome Project”. In kevles and Hood 1992, 281409.Google Scholar
Kittler, Friedrich. 1988. The pasteurization of France. Cambridge, Mass.: Harvard University press.Google Scholar
Latour, Bruno. 1988. The pasteurization of France. Cambridge, Mass.: Harvard University press.Google Scholar
Latour, Bruno. 1992. “One More Turn after the social Turn”. In social Dimensions of science. edited by Ernan, Mcmullin. 272–92. Notre Dame, Ind: Notre Dame University press.Google Scholar
Latour, Bruno. 1993. We Have Never Been Modern. Cambridge, mass. Harvard University press.Google Scholar
Lenoir, Timothly. 1993. “Farbensehen, Tonempfindung und der Telegraph: Helmholtz und die Materialiat der Kommunikation”. In Die Experimentalisierung des Lebens edited by Hans–jorg Rheinberger and Michael Hagner. 5373. Berlin: Akademie Verlag.Google Scholar
Lévi–Strauss, Claude. 1967. Les structures élémentaries de la parenté, 2nd ed. The Hague: Moutonn.CrossRefGoogle Scholar
Monod, Jacques. 1971. Chance and Necessity: An Essy on the Natural philosophy of Modern Biology. New York. Knopf.Google Scholar
Mullis, K. F., Faloona, F, Scharf, S, Saiki, R, Horn, G, and Ehrlich, H. 1986. “Specific Enzymatic Amplification of DNA in Vitro: the polymerase Chain Reaction”. Cold spring Harbor Symposia on quantiative Biology. 51. 263–73.CrossRefGoogle ScholarPubMed
Pauling, , Linus, C., Itano, H. A., Singer, S. J., and Wells, I. C.. 1949. “Sickle–cell Anemia, a Molecular Disease”. since 110. 543.Google ScholarPubMed
Pauly, , Philip, J. 1987. Controlling Life:Jacques Loeb and the Engineering Ideal in Biology. New York: Oxford University Press.Google Scholar
Rabinow, Paul. 1995. What is PCR? Bio–technology Emergent. Manuscript.Google Scholar
Rheinberger, Hans–jorg. 1995. “from microsomes to Ribosomes:strategies of representation Journal of the History of Biology” 28, in pressGoogle Scholar
Schwartz, D. C. and Cantor, C. R.. 1984. “Separetion of Yeast chromosome”; Engineering and science 32. 813.Google Scholar
“Sized DNAs by Pulsed field Gel Electrophories” cell 37. 6775.CrossRefGoogle Scholar
Serres, Michel. 1969. Le control natural. Paris: Francois Bourin.Google Scholar
Sinsheimer, Robert. 1969. “The prospect of Genetic Change”. Engineering and science 32. 813.Google Scholar
Smith, Lloyd M.,Sanders, Jane Z.,Kaiser, Robert J., Peter, Hughes, Chris, Dodd, charles, R.Connell, Cheryl, Heiner, Stephen, B.H.Kent, Leroy, E. Hood. 1986. “Fluorescence Detection in Automated DNA Sequencing Analysis”. Nature 321: 674–79.CrossRefGoogle Scholar
Stent, Gunther. 1968. “That was the Molecular Biology That Was”. Science 160: 390–95.CrossRefGoogle ScholarPubMed
Timoféeff-Ressovsky, Nikolaj W. 1934. “The Experimental Production of Mutations”. Biological Reviews 9: 411–57.CrossRefGoogle Scholar
Wingerson, Lois. 1991. Mapping Our Genes.New York:Penguin.Google Scholar