Those who criticize the theory of thought-styles do admit their existence, but would rather see them as an obstacle to an “objective” perception, a kind of malum necessarium to be eliminated. Through an analysis of the example of serology it is, however, possible to demonstrate that the specific sociological structure of the community of serologists and the history of this discipline are intrinsically connected with a particular serological thought-style, and that the very content of scientific knowledge in this discipline stems from its thought-style. It is impossible even to imagine a styleless scientific knowledge.