This paper has many aims. It proposes, first of all, to cover some of the research that has gone into the Eucharistic Prayer, especially its genesis in Roman Catholic circles. It has been a topic of interest for most of this century, but particularly so in the last twenty years. It aims to discuss the spirituality of the Prayer and its relationship to practical piety and to show the relationship between the Liturgy of the Word, the Gospel tradition, and the Eucharistic Prayer as our response to the Word of God. Lastly, this paper aims to uncover something of the theological richness of this Prayer and at the same time to show its roots in the human condition. In covering this research the paper also aims at pinpointing its constituent elements. Liturgically speaking, the Eucharistic Prayer is central: it represents the Christian response to his God at his most central and sacred moment. It is a topic with a long history. It was discussed particularly at the Reformation and in the Reformed circles was one of the casualties of the older tradition. It is a topic, the study of which has produced some conclusions. There has been a rather widespread reform of the Eucharistic Prayer in many churches. This is especially clear in the renewal of the Roman Catholic tradition and in the proposals of the Anglican Series Three.