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The Dimensions of Schizophrenia Phenomenology Not one or two, at least three, perhaps four

Published online by Cambridge University Press:  02 January 2018

Mark F. Lenzenweger  and
Robert H. Dworkin
Mark F. Lenzenweger*
Affiliation:
Laboratory of Experimental Psychopathology, Cornell University, and Department of Psychiatry, Cornell University Medical College, New York, New York
Robert H. Dworkin
Affiliation:
Departments of Anesthesiology and Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York
*
Mark F. Lenzenweger, Director, Laboratory of Experimental Psychopathology, Cornell University, Van Rensselaer Hall (NG-07A), Ithaca, New York, 14853-4401 USA
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Abstract

Background

This confirmatory investigation examined the underlying structure of schizophrenia phenomenology through examination of the fit of several prominent dimensional models to observed symptom data.

Method

Confirmatory factor analysis was conducted on a correlation matrix of schizophrenia signs and symptoms derived from case history ratings of 192 individuals with schizophrenia who were the subjects in the major twin studies of schizophrenia.

Results

Schizophrenia phenomenology appears best described by four underlying factors, namely negative symptoms, premorbid social adjustment deficits, reality distortion, and disorganisation. Of interest, the premorbid deficit dimension was directly associated with negative symptoms and disorganisation, but was inversely associated with reality distortion.

Conclusions

These data clearly support the multidimensionality of schizophrenia phenomenology and provide objective support for a four-factor model over other models. This four-factor model may be useful in organising existing and future data concerning the genetic, neurobiological, neurological, and psychosocial features of schizophrenia.

Type
Papers
Information
The British Journal of Psychiatry , Volume 168 , Issue 4 , April 1996 , pp. 432 - 440
Copyright
Copyright © Royal College of Psychiatrists, 1996 

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References

Andreasen, N. C. (1981) Scale for the Assessment of Negative Symptoms (SANS). Iowa City: University of Iowa.Google Scholar
Andreasen, N. C. & Olsen, S. (1982) Negative v. positive schizophrenia: Definition and validation. Archives of General Psychiatry, 39, 789–794.Google Scholar
Andreasen, N. C., Arndt, S., Alliger, R., et al (1995) Symptoms of schizophrenia: Methods, meanings, and mechanisms. Archives of General Psychiatry, 52, 341–351.Google Scholar
Bentler, P. M. (1993) EQS: Structural Equations Program Manual. Los Angeles, CA: BMDP Statistical Software, Inc.Google Scholar
Bilder, R. M., Mukherjee, S., Rieder, R. O., et al (1985) Symptomatic and neuropsychological components of defect states. Schizophrenia Bulletin, 11, 409–419.Google Scholar
Carpenter, W. T. & Buchanan, R. W. (1989) Domains of psychopathology relevant to the study of etiology and treatment in schizophrenia. In Schizophrenia: Scientific Progress (eds Schulz, S. C. & Tamminga, C. A.), pp. 13–23. New York: Oxford University Press.Google Scholar
Crow, T. J. (1987) Two syndromes of schizophrenia as one pole of the continuum of psychosis: A concept of the nature of the pathogen and its genomic locus. In Handbook of Schizophrenia: Neurochemistry and Neuropharmacology of Schizophrenia, Vol. 2 (eds Henn, F. A. & DeLisi, L.), pp. 17–48. Amsterdam: Elsevier.Google Scholar
Dworkin, R. H. (1990) Patterns of sex differences in negative symptoms and social functioning consistent with separate dimensions of schizophrenic psychopathology. American Journal of Psychiatry, 147, 347–349.Google Scholar
Dworkin, R. H. (1992) Affective deficits and social deficits in schizophrenia. What's what? Schizophrenia Bulletin, 18, 59–64.Google Scholar
Dworkin, R. H., Lenzenweger, M. F., Moldin, S. O., et al (1988) A multidimensional approach to the genetics of schizophrenia. American Journal of Psychiatry, 145, 1077–1083.Google Scholar
Harris, J. G. Jr. (1975) An abbreviated form of the Phillips rating scale of premorbid adjustment in schizophrenia. Journal of Abnormal Psychology, 84, 129–137.Google Scholar
Joreskog, K. G. & Sorbom, D. (1993) LISREL® 8: Users reference guide. Chicago, IL: Scientific Software International, Inc.Google Scholar
Lenzenweger, M. F., Dworkin, R. H. & Wethington, E. (1989) Models of positive and negative symptoms in schizophrenia: An empirical evaluation of latent structures. Journal of Abnormal Psychology, 98, 62–70.Google Scholar
Lenzenweger, M. F., Dworkin, R. H. & Wethington, E. (1991) Examining the underlying structure of schizophrenic phenomenology. Evidence for a three-process model. Schizophrenia Bulletin, 17, 515–524.Google Scholar
Liddle, P. F. (1987) The symptoms of chronic schizophrenia: A re-examination of the positive–negative dichotomy. British Journal of Psychiatry, 151, 145–151.Google Scholar
McGlashan, T. H. & Fenton, W. S. (1992) The positive–negative distinction in schizophrenia: Review of natural history validators. Archives of General Psychiatry, 49, 63–72.Google Scholar
Strauss, J. S., Carpenter, W. T. Jr. & Bartko, J. J. (1974) The diagnosis and understanding of schizophrenia: Part III. Speculations on the processes that underlie schizophrenic signs and symptoms. Schizophrenia Bulletin, 1, 61–69.CrossRefGoogle Scholar
Tucker, L. R. & Lewis, C. A. (1973) A reliability coefficient for maximum likelihood factor analysis. Psychometrika, 38, 1–10.Google Scholar
Venables, P. H. & O'Connor, N. A. (1959) A short scale for rating paranoid schizophrenia. Journal of Mental Science, 105, 815–818.Google Scholar
Zigler, E. & Phillips, L. (1960) Social effectiveness and symptomatic behaviors. Journal of Abnormal and Social Psychology, 61, 231–238.CrossRefGoogle ScholarPubMed
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