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Eeg Features of Depressive and Schizophrenic States

Published online by Cambridge University Press:  29 January 2018

D. F. Scott
Affiliation:
EEG Department, Section of Neurological Sciences, The London Hospital, Whitechapel, London, E1 1BB
Martin S. Schwartz
Affiliation:
EEG Department, Section of Neurological Sciences, The London Hospital, Whitechapel, London, E1 1BB

Summary

25-year-old female patient with a psychotic illness lasting three months in which schizophrenia and depressive episodes occurred was studied by serial EEGs. These were coded, masked and rated in a set way without knowledge of the clinical state. It was found that the schizophrenic state was characterized by a decrease in the amount and poor organization of alpha activity, as well as the occurrence of paroxysmal phenomena in particular atypical spike and wave. In the depressive episode, alpha activity was prominent and only scanty paroxysmal features were seen. Using these criteria a series of EEGs from psychiatric patients were assessed ‘blind’ with a view to separating them into either a schizophrenic or a depressive category. This proved possible in 17 cases (9 depressive and 8 schizophrenic). In only two was the categorization completely misjudged. These results suggest that further detailed study of the EEG, possibly with computer analysis, combined with assessment of the behavioural state might not only yield useful diagnostic information but also lead to a better understanding of the underlying neurophysiological basis of certain mental disorders.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1975 

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References

Gjessing, L. R., Harding, G. F. A., Jenner, F. A. & Johannessen, N. B. (1967) The EEG in three cases of periodic catatonia. British Journal of Psychiatry, 113, 1271–82.Google Scholar
Gloor, Pierre (1969) Hans Berger on the electroencephalogram of man. Electroencephalography and Clinical Neurophysiology, Supplement 28. Amsterdam: Elsevier.Google Scholar
Harding, G. F. A. (1974) The EEG in affective disorders. In Handbook of Clinical Neurophysiology, Vol. 13. Amsterdam: Elsevier.Google Scholar
Hill, D. (1952) EEG in episodic, psychotic and psychopathic behaviour. Electroencephalography and Clinical Neurophysiology, 4, 419–42.Google Scholar
Krauthammer, W., Last, S. L., Morgan, M. H. & Prior, P. F. (1966) EEG reports—the storage of data in a computer. Electroencephalography and Clinical Neurophysiology, 21, 616.Google Scholar
Malpas, A., Legg, N. J. & Scott, D. F. (1974) Effects of hypnotics on anxious patients. British Journal of Psychiatry, 124, 482–4.Google Scholar
Monroe, R. R. (1970) Episodic Behavioural Disorders—A Psychodynamic and Neurophysiology Analysis. Cambridge, Mass., U.S.A.: Harvard University Press.Google Scholar
Schwartz, M. S. & Scott, D. F. (1974) EEG features of schizophrenic and depressive illness. Electroencephalography and Clinical Neurophysiology, 37, 325.Google Scholar
Slater, E., Beard, A. W. & Glithero, E. (1963) The schizophrenia-like psychoses of epilepsy. British Journal of Psychiatry, 109, 95150.Google Scholar
Struve, F. A., Klein, D. F., Kishare, R. & Saraf, F. (1972) Electroencephalographic correlates of suicide ideation and attempts. Archives of General Psychiatry, 27, 363–5.Google Scholar
Swash, M. & Rowan, A. J. (1972) Electroencephalographic criteria of hypocalcaemia and hypercalcemia. Archives of Neurology, 26, 218–28.Google Scholar
Wing, J. K., Birley, J. L. T., Cooper, J. E., Graham, P. & Issaacs, A. D. (1967) Reliability of a procedure for measuring and classifying ‘present psychiatric states’. British Journal of Psychiatry, 113, 499516.Google Scholar
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