Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-13T07:05:56.519Z Has data issue: false hasContentIssue false
  • English
  • Français

Gilles de la Tourette Syndrome in the Middle East

Report of a Cohort and a Multiply Affected Large Pedigree

Published online by Cambridge University Press:  02 January 2018

Mary M. Robertson  and
M. R. Trimble
Mary M. Robertson*
Affiliation:
Institute of Neurology, and Academic Department of Psychiatry, UCMSM, Middlesex Hospital, Mortimer Street, London W1N 8AA
M. R. Trimble
Affiliation:
The National Hospital for Nervous Diseases, Queen Square, London WC1N 3BG
*
* Correspondence
Get access Rights & Permissions [Opens in a new window]

Abstract

In a cohort of five patients from the Middle East with the Gilles de la Tourette syndrome, family history of a tic disorder or the Gilles de la Tourette syndrome was positive in three cases. In one of these there was a multiply affected pedigree spanning six generations. The phenomenology of the syndrome is the same as that described in Western reports. The familial pattern of inheritance and cross-cultural similarity emphasise the biological factors in the aetiology of the syndrome.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 158 , Issue 3 , March 1991 , pp. 416 - 419
Copyright
Copyright © Royal College of Psychiatrists, 1991 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Comings, D. E. & Comings, B. G. (1987) Hereditary agoraphobia and obsessive-compulsive behaviour in relatives of patients with Gilles de la Tourette syndrome. British Journal of Psychiatry, 151, 195–199.CrossRefGoogle Scholar
El-Assra, A. (1987) A case of Gilles de la Tourette's syndrome in Saudi Arabia. British Journal of Psychiatry, 151, 397–398.Google Scholar
Kurlan, R. Behr, J. Medved, L. et al (1986) Familial Tourette syndrome: report of a large pedigree and potential for linkage analysis. Neurology, 36, 772–776.Google Scholar
Lees, A. J. Robertson, M. M. Trimble, M. R. et al (1984) A clinical study of the Gilles de la Tourette syndrome in children in the United Kingdom. Journal of Neurology, Neurosurgery, and Psychiatry, 47, 1–8.CrossRefGoogle ScholarPubMed
Pauls, D. L. & Leckman, J. F. (1986) The inheritance of Gilles de la Tourette syndrome and associated behaviours. New England Journal of Medicine, 315, 993–997.Google Scholar
Pauls, D. L. Cohen, D. J. Heimbuch, R. et al (1981) Familial patterns and transmission of Gilles de la Tourette syndrome and multiple tics. Archives of General Psychiatry, 38, 1091–1093.Google Scholar
Pauls, D. L. Leckman, J. F. Towbin, K. E. et al (1986 a) A possible genetic relationship exists between Tourette syndrome and obsessive-compulsive disorder. Psychopharmacology Bulletin, 11, 730–733.Google Scholar
Pauls, D. L. Towbin, K. E. Leckman, J. F. et al (1986 b) Gilles de la Tourette syndrome and obsessive–compulsive disorder. Archives of General Psychiatry, 43, 1180–1182.Google Scholar
Robertson, M. M. (1989) The Gilles de la Tourette syndrome: the current status. British Journal of Psychiatry, 154, 147–169.Google Scholar
Robertson, M. M. & Gourdie, A. (1990) Familial Tourette syndrome in a large British pedigree. Associated psychopathology, severity of Tourette's and potential for linkage analysis. British Journal of Psychiatry, 156, 515–522.Google Scholar
Robertson, M. M. Trimble, M. R. & Lees, A. J. (1988) The psychopathology of the Gilles de la Tourette syndrome. British Journal of Psychiatry, 152, 383–390.Google Scholar
Robertson, M. M. Trimble, M. R. & Lees, A. J. (1989) Self-injurious behaviour and the Gilles de la Tourette syndrome: a clinical study and review of the literature. Psychological Medicine, 19, 611–625.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.