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Growth Hormone After Trh in Women with Depressive Illness

Published online by Cambridge University Press:  29 January 2018

P. Linkowski ,
H. Brauman  and
J. Mendlewicz
P. Linkowski
Affiliation:
Department of Psychiatry, Hôpital Erasme, Free University of Brussels
H. Brauman
Affiliation:
Laboratory of Clinical Biology, Hôpital Brugmann, Free University of Brussels
J. Mendlewicz
Affiliation:
Hôpital Erasme, Free University of Brussels, 808 route de Lennick, 1070 Brussels, Belgium
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Summary

Plasma growth hormone (GH) release after TRH injection was investigated in 27 unipolar and 23 bipolar depressive women, and in 39 normal female controls matched for age, sex and menopausal status. Peaks of GH secretion after TRH were observed in some depressive patients as well as in some normal controls, but there were no significant differences in GH response after TRH administration between patients and controls. The implications of these findings are discussed in reference to such factors as non-specific stress responses and abnormal neuroendocrine circadian rhythms in affectively ill patients.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 137 , Issue 3 , September 1980 , pp. 229 - 232
Copyright
Copyright © Royal College of Psychiatrists, 1980 

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References

Brambilla, F., Smeraldi, E., Sacchetti, E., Negri, F., Cocchi, D. & Muller, E. (1978) Deranged anterior pituitary responsiveness to hypothalamic hormones in depressed patients. Archives of General Psychiatry, 35, 1231–8.CrossRefGoogle ScholarPubMed
Brown, G. M., Seggie, J. A., Chambers, J. W. & Ettigi, P. G. (1978) Psychoendocrinology and growth hormone. Psychoneuroendocrinology, 3, 131–55.CrossRefGoogle ScholarPubMed
Feighner, Y. P., Robbins, E., Guze, S. B., Woodruff, R. A., Winokur, F. & Munoz, R. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–63.CrossRefGoogle ScholarPubMed
Gold, M. S., Pottash, A. L. C., Sweeney, D. R., Martin, D. M. & Davies, R. K. (1980) Further evidence of hypothalamic pituitary dysfunction in anorexia nervosa. American Journal of Psychiatry, 137, 1, 101–2.Google ScholarPubMed
Gonzalez-Barcena, D., Kastin, A. J., Schalch, D. S., Torres-Zamora, M., Perez-Basten, E., Kato, A. & Schally, A. V. (1973) Response to thyrotrophin releasing hormone in patients with renal failure and after infusion in normal men. Journal of Clinical Endocrinology and Metabolism, 36, 117–20.CrossRefGoogle ScholarPubMed
Irie, M. & Tsushima, L. (1972) Increase of serum growth hormone concentration following thyrotrophin-releasing hormone injection in patients with acromegaly or gigantism. Journal of Clinical Endocrinology and Metabolism, 35, 97–100.CrossRefGoogle ScholarPubMed
Maeda, K., Kato, Y., Ohgo, S., Chichara, K., Yoshimoto, Y., Yamaguchi, N., Kuromaru, S. & Imura, H. (1975) Growth hormone and prolactin release after injection of thyrotrophin-releasing hormone in patients with depression. Journal of Clinical Endocrinology and Metabolism, 40, 501–5.CrossRefGoogle ScholarPubMed
Maeda, K., Kato, Y., Yamaguchi, N., Chichara, K., Ohgo, S., Iwasaki, Y., Yoshimoto, Y., Moridera, K., Kuromaru, S. & Imura, H. (1976) Growth hormone release following thyrotrophin releasing hormone injection in patients with anorexia nervosa. Acta Endocrinologica, 81, 1–8.Google ScholarPubMed
Mendlewicz, J., Linkowski, P. & Brauman, H. (1979) TSH responses to TRH in women with unipolar and bipolar depression. Lancet, ii, 1079–80.CrossRefGoogle ScholarPubMed
Mendlewicz, J. (1980) Orcadian changes in pituitary hormone levels in manic depressive illness. In Hormones and the Brain (ed. de Wied and Van Keep). Lancaster: MTP Press, in press.Google Scholar
Miyabo, S., Isada, T., Ajato, T., Mizushima, N. & Vena, K. (1976) Growth hormone and Cortisol responses to psychological stress: comparison of normal and neurotic subjects. Journal of Clinical Endocrinology and Metabolism, 42, 1158–62.CrossRefGoogle ScholarPubMed
Panerai, A. E., Salerno, F. & Maneschi, M. (1977) Growth hormone and prolactin responses to thyrotrophin releasing hormone in patients with severe liver disease. Journal of Clinical Endocrinology and Metabolism, 45, 134–40.CrossRefGoogle ScholarPubMed
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