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Negative Symptoms, Tardive Dyskinesia and Depression in Chronic Schizophrenia

Published online by Cambridge University Press:  06 August 2018

Thomas R.E. Barnes ,
Peter F. Liddle ,
David A. Curson  and
Meena Patel
Thomas R.E. Barnes
Affiliation:
Charing Cross and Westminster Medical School, London; The Academic Unit, Horton Hospital, Epsom
Peter F. Liddle
Affiliation:
Charing Cross and Westminster Medical School, London; The Academic Unit, Horton Hospital, Epsom
David A. Curson
Affiliation:
Charter Clinic, Chelsea, London and Riverside Health Authority, London, Bowden House Clinic, Harrow-on-the Hill, Middlesex
Meena Patel
Affiliation:
Shenley Hospital, Herts; Formerly Registrar at Horton Hospital, Epsom, Surrey
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Extract

The existence of a definable and distinct negative syndrome within schizophrenia remains to be established (Barnes & Liddle, 1989). Addressing this issue, Sommers (1985) discusses three stages required to demonstrate validity for a syndrome. These are first, that the signs and symptoms must be shown to occur together. Second, operational definitions must be developed which will reliably identify and rate and features, and third, the relationships between the syndrome and other variables must be shown to be predictable. With respect to the second and third stages, this paper reports briefly on two recent studies which explored the relationship between negative features and other clinical features, specifically depressive symptoms and drug-induced movement disorder. The results of such studies (see also McKenna et al; and Lindenmayer & Kay, this volume) allow some assessment of the ability of the rating methods used to discriminate between negative symptoms and features such as drug-related bradykinesia and depressive features.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 155 , Issue S7: Negative Symptoms in Schizophrenia , November 1989 , pp. 99 - 103
Copyright
Copyright © Royal College of Psychiatrists, 1989 

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References

Ananth, J. & Ghadirian, A.M. (1980) Drug induced mood disorder. International Pharmacopsychiatry, 15, 58–73.CrossRefGoogle Scholar
Andreasen, N.C. (1982) Negative symptoms in schizophrenia. Archives of General Psychiatry, 39, 784–788.Google Scholar
Asberg, M., Montgomery, S.A., Perris, C., et al (1978) A comprehensive psychopathological rating scale. Acta Psychiatrica Scandinavica, 57, (Suppl. 271), 5–27.CrossRefGoogle Scholar
Baldessarini, R.J. (1978) Chemotherapy. In The Harvard Guide to Modern Psychiatry (ed. Nicholi, A.M.). Cambridge, Mass.: Harvard University Press.Google Scholar
Barnes, T.R.E. (1989) A rating scale for drug-induced akathisia. British Journal of Psychiatry, 154, 672–676.CrossRefGoogle ScholarPubMed
Barnes, T.R.E. & Liddle, P.F. (1985) Tardive dyskinesia: implications for schizophrenia? In Schizophrenia: New Pharmacological and Clinical Developments (eds A.A. Schiff, Sir Martin Roth & H.L. Freeman). Royal Society of Medicine International Congress and Symposium Series No. 94, pp. 81–87.Google Scholar
Barnes, T.R.E. & Liddle, P.F. (1989) The evidence for the validity of negative symptoms. In Modern Problems of Pharmacopsychiatry Vol. 24: Positive and Negative Symptoms and Syndromes (ed. Andreasen, N.C.). Basel: Kargel (in press).Google Scholar
Barnes, T.R.E., Kidger, T. & Gore, S.M. (1983) Tardive dyskinesia: a 3-year follow-up study. Psychological Medicine, 13, 71–81.Google Scholar
Barnes, T.R.E., Curson, D.A., Liddle, P.F., et al (1989) The nature and prevalence of depression in chronic schizophrenic in-patients. British Journal of Psychiatry, 154, 486–491.Google Scholar
Barnes, T.R.E. & Trauer, T. (1982) Reliability and validity of a tardive dyskinesia videotape rating technique. British Journal of Psychiatry, 140, 508–515.CrossRefGoogle ScholarPubMed
Beck, A.T., Ward, C.H., Mendelson, M., et al (1961) An inventory for measuring depression. Archives of General Psychiatry, 4, 561–571.Google Scholar
Craig, T.J., Richardson, M.A., Pass, R., et al (1985) Measurement of mood and affect in schizophrenic inpatients. American Journal of Psychiatry, 142, 1272–1277.Google Scholar
Davis, J.M. (1976) Comparative doses and costs of antipsychotic medication. Archives of General Psychiatry, 33, 858–861.Google Scholar
Galdi, J. (1983) The causality of depression in schizophrenia. British Journal of Psychiatry, 142, 621–624.CrossRefGoogle ScholarPubMed
Jeste, D.V., Karson, C.N. & Wyatt, R.J. (1984) Movement disorders and psychopathology. In Neuropsychiatric Movement Disorders (eds Jeste, D.V. & Wyatt, R.J.). Washington DC: American Psychiatric Publications.Google Scholar
Kidger, T., Barnes, T.R.E., Trauer, T. et al (1980) Subsyndromes of tardive dyskinesia. Psychological Medicine, 10, 513–520.CrossRefGoogle ScholarPubMed
Knights, A. & Hirsch, S.R. (1981) ‘Revealed’ depresssion and drug treatment for schizophrenia. Archives of General Psychiatry, 38, 806–811.Google Scholar
Krawiecka, M., Goldberg, D. & Vaughan, M. (1977) A standardised psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatrica Scandinavica, 55, 299–308.Google Scholar
Manschrek, T.C. & Ames, D. (1984) Neurologic features and psychopathology in schizophrenic disorders. Biological Psychiatry, 19, 703–719.Google Scholar
Manschrek, T.C., Maher, B.A., Bucklos, M.E., et al (1982) Disturbed voluntary motor activity in schizophrenic disorder. Psychological Medicine, 12, 73–84.Google Scholar
McGlashan, T.H. & Carpenter, W.T. (1976a) An investigation of the postpsychotic depressive syndrome, American Journal of Psychiatry, 133, 14–19.Google Scholar
McGlashan, T.H., Carpenter, W.T. (1976b) Postpsychotic depression in schizophrenia. Archives of General Psychiatry, 33, 231–239.Google Scholar
Montgomery, S. & Asberg, M. (1979) A new depression scale designed to be sensitive to change. British Journal of Psychiatry, 134, 382–389.Google Scholar
Opler, L.A., Kay, S.R., Rosado, V., et al (1984). Positive and negative syndromes in chronic schizophrenic patients. Journal of Nervous and Mental Disease, 172, 371–325.CrossRefGoogle Scholar
Prosser, E.S., Csernansky, J.G., Kaplan, J., et al (1987). Depression, Parkinsonian symptoms and negative symptoms in schizophrenics treated with neuroleptics. Journal of Nervous and Mental Disease, 175, 100–105.Google Scholar
Rifkin, A., Quitkin, F. & Klein, S.F. (1975). Akinesia, a poorly recognised drug-induced extrapyramidal behaviour disorder. Archives of General Psychiatry, 32, 672–674.Google Scholar
Roth, S. (1970). The seemingly ubiquitous depression following acute schizophrenic episodes, a neglected area of clinical discussion. American Journal of Psychiatry, 127, 91–98.Google Scholar
Simpson, G.M. & Angus, J.W.S. (1970). A rating scale for extrapyramidal side-effects. Acta Psychiatrica Scandinavica, 212 (Suppl. 44), 11–19.Google Scholar
Sommers, A.S. (1985) ‘Negative symptoms': conceptual and methodological problems. Schizophrenia Bulletin, 11, 364–379.Google Scholar
Stern, M.J., Pillsbury, J.A. & Sonnenberg, S.M. (1972). Postpsychotic depression in schizophrenia. Comprehensive Psychiatry, 13, 591–598.Google Scholar
Van Putten, T. & May, P.R.A. (1978) ‘Akinetic depression’ in schizophrenia. Archives of General Psychiatry, 35, 1101–1107.Google Scholar
Waddington, J.L. & Youssef, H.A. (1986) An unusual cluster of tardive dyskinesia in schizophrenia: association with cognitive dysfunction and negative symptoms. American Journal of Psychiatry, 143, 1162–1165.Google Scholar
Waddington, J.L. & Youssef, H.A. (1987) Tardive dyskinesia in schizophrenia and other disorders: associations with ageing, cognitive dysfunction and structural brain pathology in relation to neuroleptic exposure. Human Psychopharmacology, 2, 11–22.Google Scholar
Wing, J.K., Cooper, J.E. & Sartorius, N. (1974) The measurement and classification of psychiatric symptoms. London: Cambridge University Press.Google Scholar
Yarden, P.E. & Discipio, W. (1971) Abornmal movements and progress in schizophrenia. American Journal of Psychiatry, 128, 317–323.Google Scholar
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