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Obstetric Complications, the Putative Familial-Sporadic Distinction, and Tardive Dyskinesia in Schizophrenia

Published online by Cambridge University Press:  02 January 2018

Eadbhard O'Callaghan ,
Conall Larkin ,
Anthony Kinsella  and
John L. Waddington
Eadbhard O'Callaghan
Affiliation:
Cluain Mhuire Family Centre, Co. Dublin, St Stephen's Green, Dublin 2, Ireland
Conall Larkin
Affiliation:
Cluain Mhuire Family Centre, Co. Dublin, St Stephen's Green, Dublin 2, Ireland
Anthony Kinsella
Affiliation:
Dublin Institute of Technology, St Stephen's Green, Dublin 2, Ireland
John L. Waddington*
Affiliation:
Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, St Stephen's Green, Dublin 2, Ireland
*
∗Correspondence
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Abstract

Obstetric complications were more common in the histories of those schizophrenic outpatients without a family history of psychiatric disorder, and were associated with an earlier onset of their illness. Those patients with tardive dyskinesia were more likely to have a family history of psychiatric disorder, less likely to have experienced obstetric complications, and showed greater cognitive deficit. Obstetric complications should be considered in juxtaposition with genetic factors in evaluating the putative familial-sporadic distinction in schizophrenia. Additionally, familial/genetic factors appear to contribute to vulnerability to tardive dyskinesia.

Type
Papers
Information
The British Journal of Psychiatry , Volume 157 , Issue 4 , October 1990 , pp. 578 - 584
Copyright
Copyright © Royal College of Psychiatrists, 1990 

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