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On the value of P300 Event-Related Potentials in the Differential Diagnosis of Dementia

Published online by Cambridge University Press:  29 January 2018

J. P. J. Slaets  and
C. Fortgens Jr.
J. P. J. Slaets*
Affiliation:
Psychiatric Centre Rosenburg, Oude Haagweg 377, 2552 GB, The Hague, The Netherlands
C. Fortgens Jr.
Affiliation:
Psychiatric Centre Rosenburg, Oude Haagweg 377, 2552 GB, The Hague, The Netherlands
*
∗Correspondence
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Summary

The possible value of event-related potentials (ERPs) in the differential diagnosis of dementia was investigated in a group of 42 demented elderly patients, 29 non-demented elderly patients, and 10 healthy young controls. The auditory evoked potentials were elicited by using target and non-target auditory stimuli. There was no significant difference in N100 and P200 latency between these groups. Our results indicate an age-related increase of P300 latency of 0.3 msec/year in the non-demented subjects. There was no significant difference in P300 latency between demented and non-demented patients, and the latencies vary widely within the groups of elderly patients.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 145 , Issue 6 , December 1984 , pp. 652 - 656
Copyright
Copyright © 1984 The Royal College of Psychiatrists 

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