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A Study of Naloxone with Schizophrenic and Manic Patients

Published online by Cambridge University Press:  29 January 2018

Brij B. Sethi  and
Rudra Prakash
Brij B. Sethi*
Affiliation:
Department of Psychiatry, King George's Medical College, Lucknow–226 003, India
Rudra Prakash
Affiliation:
Department of Psychiatry, King George's Medical College, Lucknow–226 003, India
*
∗ Correspondence and reprints: 23, Ashok Marg, Lucknow–226 001, India.
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Summary

Eleven schizophrenic and three manic patients were randomly administered 0.3 mg/Kg b.wt. of naloxone or placebo in a drug-free state using a double blind procedure. BPRS and CGI were employed for making periodic assessment of mental status; the MRS was additionally used for manic patients. The authors discuss their findings, which are essentially negative.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 138 , Issue 6 , June 1981 , pp. 501 - 503
Copyright
Copyright © Royal College of Psychiatrists, 1981 

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Footnotes

∗∗

Research Fellow, Department of Psychiatry, Tennessee Neuropsychiatric Institute, 1501 Murfreesboro Road, Nashville, Tennessee 37217, USA.

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