Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-06T11:45:55.923Z Has data issue: false hasContentIssue false
  • English
  • Français

Variations in Body Water during Recovery from Depression

Published online by Cambridge University Press:  29 January 2018

R. P. Hullin ,
Angela D. Bailey ,
R. McDonald ,
G. A. Dransfield  and
H. B. Milne
R. P. Hullin
Affiliation:
University of Leeds
Angela D. Bailey
Affiliation:
University of Leeds
R. McDonald
Affiliation:
High Royds Hospital, Menston, Ilkley, Yorkshire
G. A. Dransfield
Affiliation:
High Royds Hospital, Menston, Ilkley, Yorkshire
H. B. Milne
Affiliation:
High Royds Hospital, Menston, Ilkley, Yorkshire
Get access Rights & Permissions [Opens in a new window]

Extract

Reports of significant changes in water and electrolytes during recovery from depression may provide insight into important physiological factors in depressive illnesses. Brown et al. (1963) demonstrated an increase in the extracellular fluid volume in 22 of 28 patients suffering from primary depressive disorders treated with E.C.T. or imipramine. The findings of these authors, which were discussed in relation to previous work on sodium metabolism and water balance in depressive disorders, were thought to support the idea of a shift of fluid from intracellular to extracellular spaces during the response to treatment. Coppen and Shaw (1963) found an increase in total body water, extracellular fluid and a decrease in the residual sodium space on recovery from depression.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 113 , Issue 499 , June 1967 , pp. 573 - 583
Copyright
Copyright © Royal College of Psychiatrists, 1967 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Altschule, M. D., Ascoli, I., and Tillotson, K. J. (1949). “Extracellular fluid and plasma volumes in depressed patients given electric shock therapy.” Arch. Neurol. Psychiat., (Chic), 62, 618–623.CrossRefGoogle Scholar
Boling, E. A. (1963). “Determination of K42, Na24, Br82 and tritiated water concentration in man.? Ann. N.Y. Acad. Sci., 110, 246–254.Google Scholar
Brown, D. G., Hullin, R. P., and Roberts, J. M. (1963). “Fluid distribution and the response of depression to E.C.T. and imipramine.” Brit. J. Psychiat., 109, 395–398.Google Scholar
Coppen, A., and Shaw, D. M. (1963). “Mineral metabolism in melancholia.” Brit. med. J., ii, 1439–1444.CrossRefGoogle Scholar
Fallot, P., Aerberhardt, A., and Masson, J. (1957). “Méthode de dosage de l'eau tritiée et ses applications en clinique humaine.” Int. J. appl. Radiat. Isotopes, 1, 237–245.CrossRefGoogle Scholar
Foy, J. M., and Schnieden, H. (1960). “Estimation of total body water (virtual tritium space) in the rat, cat, rabbit, guinea-pig and man, and of the biological half-life of tritium in man.” J. Physiol. Lond., 154, 169–176.CrossRefGoogle Scholar
Hullin, R. P., Bailey, A. D., Dransfield, G. A., Mc-Donald, R., and Milne, H. B. (1967a). “Body water variations in manic-depressive psychosis.” Brit. J. Psychiat., 113, 584–592.Google Scholar
Hullin, R. P., Bailey, A. D., Dransfield, G. A., Mc-Donald, R., and Milne, H. B. (1967b). “Variations in 11-hydroxycorticosteroids in depression and manic-depressive psychosis.” Brit. J. Psychiat., 113, 593–600.Google Scholar
Langham, W. H., Eversole, W. J., Hayes, F. N., and Trujillo, T. T. (1956). “Assay of tritium activity in body fluids with use of a liquid scintillation system.” J. Lab. clin. Med., 47, 819–825.Google Scholar
Leibman, J. Gotch, F. A., and Edelman, I. S. (1960). “Tritium assay by liquid scintillation spectometry.” Circulation Res., 8, 907–912.Google Scholar
Natrella, M. G. (1963). Experimental Statistics. National Bureau of Standards Handbook 91, U.S. Government Printing Office, Washington.Google Scholar
Pace, N., Kline, L., Schachman, H. K., and Harfenist, M. (1947). “Studies on body composition: Use of radioactive hydrogen for measurement in vivo of total body water.” J. bid. Chem., 168, 459–469.Google Scholar
Spector, W. S. (1956). Handbook of Biological Data. W. B. Saunders Co., London.Google Scholar
Udekwu, A. O., Kozoll, D. D., and Meyer, K. A. (1963). “Determination of total body water with tritium oxide.” J. nucl. Med., 4, 60–9.Google Scholar
Vaughan, B. E., and Boling, E. A. (1961). “Rapid assay procedures for tritium-labelled water in body fluids.” J. Lab. clin. Med., 57, 159–164.Google Scholar
Werbin, H., Chaikoff, I. L., and Imada, M. R. (1959). “Rapid sensitive method for determining H3-water in body fluids by liquid scintillation spectrometry.” Proc. Soc. exp. Biol. Méd., 102, 8–12.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.