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The future of early disease detection? Applications of electronic nose technology in otolaryngology

Published online by Cambridge University Press:  02 June 2010

N Charaklias ,
H Raja ,
M L Humphreys ,
N Magan  and
C A Kendall
N Charaklias
Affiliation:
ENT Department, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK Biophotonics Research Unit, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK Cranfield Health, Cranfield University, UK
H Raja
Affiliation:
ENT Department, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK
M L Humphreys
Affiliation:
Biophotonics Research Unit, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK Cranfield Health, Cranfield University, UK
N Magan
Affiliation:
Cranfield Health, Cranfield University, UK
C A Kendall*
Affiliation:
Biophotonics Research Unit, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK Cranfield Health, Cranfield University, UK
*
Address for correspondence: Dr C A Kendall, Royal Society Dorothy Hodgkin Fellow, Biophotonics Research Unit, Gloucestershire Hospitals NHS Foundation Trust, Great Western Road, Gloucester GL1 3NN, UK. Fax: +44 (0)8454 225485 E-mail: c.kendall@medical-research-centre.com
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Abstract

Introduction:

Recent advances in electronic nose technology, and successful clinical applications, are facilitating the development of new methods for rapid, bedside diagnosis of disease. There is a real clinical need for such new diagnostic tools in otolaryngology.

Materials and methods:

We present a critical review of recent advances in electronic nose technology and current applications in otolaryngology.

Results:

The literature reports evidence of accurate diagnosis of common otolaryngological conditions such as sinusitis (acute and chronic), chronic suppurative otitis media, otitis externa and nasal vestibulitis. A significant recent development is the successful identification of biofilm-producing versus non-biofilm-producing pseudomonas and staphylococcus species.

Conclusion:

Electronic nose technology holds significant potential for enabling rapid, non-invasive, bedside diagnosis of otolaryngological disease.

Keywords

Electronic Nose (E-Nose)DiagnosisBiofilms
Type
Review Article
Information
The Journal of Laryngology & Otology , Volume 124 , Issue 8 , August 2010 , pp. 823 - 827
Copyright
Copyright © JLO (1984) Limited 2010

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