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Carbon monoxide poisoning: an unusual cause of dizziness

Published online by Cambridge University Press:  14 April 2010

R Lakhani*
Affiliation:
Department of Otolaryngology, Wexham Park Hospital, Slough, UK
N Bleach
Affiliation:
Department of Otolaryngology, Wexham Park Hospital, Slough, UK
*
Address for correspondence: Mr Raj Lakhani, Department of Otolaryngology, Wexham Park Hospital, Slough SL2 4HH, UK. Fax: +44 (0)1753 633 051 E-mail: drlakhani@doctors.net.uk

Abstract

Objective:

We report an unusual case of dizziness caused by carbon monoxide poisoning.

Case report:

A 55-year-old man was referred to an ENT surgeon with dizziness. The patient described vague, non-specific symptoms not consistent with a diagnosis of benign paroxysmal positional vertigo, labyrinthitis or Ménière's disease. It emerged later that the patient had been suffering from carbon monoxide poisoning from a leaky gas hot water boiler in his house. After having the boiler fixed, the patient's symptoms completely resolved.

Conclusion:

When the more common causes of dizziness cannot be found, less common but important differential diagnoses, such as carbon monoxide poisoning, should be considered.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 2010

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References

1Neuhauser, HK. Epidemiology of vertigo. Curr Opin Neurol 2007;20:40–6CrossRefGoogle ScholarPubMed
2Gas Safety – Carbon Monoxide Awareness. In: http://www.hse.gov.uk/gas/domestic/co.htm [15 October 2009]Google Scholar
3Ernst, A, Zibrak, JD. Carbon monoxide poisoning. N Engl J Med 1998;339:1603–8CrossRefGoogle ScholarPubMed
4National poisons information service (2009) TOXBASE Carbon monoxide. In: http://www.toxbase.org/ [15 October 2009]Google Scholar
5Fawcett, TA, Moon, RE, Fracica, PJ, Mebane, GY, Theil, DR, Piantadosi, CA. Warehouse workers' headache. Carbon monoxide poisoning from propane-fueled forklifts. J Occup Med 1992;34:1215Google ScholarPubMed
6Choi, IS. Carbon monoxide poisoning: systemic manifestations and complications. J Korean Med Sci 2001;16:253–61CrossRefGoogle ScholarPubMed
7Weaver, LK. Clinical practice. Carbon monoxide poisoning. N Engl J Med 2009;360:1217–25CrossRefGoogle ScholarPubMed
9Hampson, NB, Weaver, LK. Carbon monoxide poisoning: a new incidence for an old disease. Undersea Hyperb Med 2007;34:163–8Google ScholarPubMed
10Boehning, D, Moon, C, Sharma, S, Hurt, KJ, Hester, LD, Ronnett, GV et al. Carbon monoxide neurotransmission activated by CK2 phosphorylation of hemeoxygenase-2. Neuron 2003 25;40:129–37CrossRefGoogle Scholar
11Mannaioni, PF, Vannacci, A, Masini, E. Carbon monoxide: the bad and the good side of the coin, from neuronal death to anti-inflammatory activity. Inflamm Res 2006;55:261–73CrossRefGoogle ScholarPubMed
12Thom, SR. Carbon monoxide pathophysiology and treatment. In: Neuman, TS, Thom, SR, eds. Physiology and Medicine of Hyperbaric Oxygen Therapy. Philadelphia: Saunders Elsevier, 2008;321–47CrossRefGoogle ScholarPubMed
13Alonso, JR, Cardellach, F, López, S, Casademont, J, Miró, O. Carbon monoxide specifically inhibits cytochrome c oxidase of human mitochondrial respiratory chain. Pharmacol Toxicol 2003;93:142–6CrossRefGoogle ScholarPubMed
14Cronje, FJ, Carraway, MS, Freiberger, JJ, Suliman, HB, Piantadosi, CA. Carbon monoxide actuates O(2)-limited heme degradation in the rat brain. Free Radic Biol Med 2004;37:1802–12CrossRefGoogle ScholarPubMed
15Thom, SR, Bhopale, VM, Han, ST, Clark, JM, Hardy, KR. Intravascular neutrophil activation due to carbon monoxide poisoning. Am J Respir Crit Care Med 2006;174:1239–48CrossRefGoogle ScholarPubMed
16Sources of Carbon Monoxide in the Environment. In: http://www.who.int/ipcs/publications/ehc/ehc_213_part_2.pdf [15 October 2009]Google Scholar
17Scherer, G. Carboxyhemoglobin and thiocyanate as biomarkers of exposure to carbon monoxide and hydrogen cyanide in tobacco smoke. Exp Toxicol Pathol 2006;58:101–24CrossRefGoogle ScholarPubMed
18Walker, E, Hay, A. Carbon monoxide poisoning. BMJ 1999;319:1082–3CrossRefGoogle ScholarPubMed