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Determination of remnant thyroid volume: comparison of ultrasonography, radioactive iodine uptake and serum thyroid-stimulating hormone level

Published online by Cambridge University Press:  03 July 2007

Y Erbil ,
U Barbaros ,
A Salmaslıoglu ,
H Issever ,
M Tukenmez ,
I Adalet ,
A Bozbora ,
S Özarmagan  and
S Tezelman
Y Erbil*
Affiliation:
Department of General Surgery, Medical Faculty, Istanbul University, Turkey
U Barbaros
Affiliation:
Department of General Surgery, Medical Faculty, Istanbul University, Turkey
A Salmaslıoglu
Affiliation:
Department of Radiology, Medical Faculty, Istanbul University, Turkey
H Issever
Affiliation:
Department of Public Health and Medical Faculty, Istanbul University, Turkey
M Tukenmez
Affiliation:
Department of General Surgery, Medical Faculty, Istanbul University, Turkey
I Adalet
Affiliation:
Department of Nuclear Medicine, Medical Faculty, Istanbul University, Turkey
A Bozbora
Affiliation:
Department of General Surgery, Medical Faculty, Istanbul University, Turkey
S Özarmagan
Affiliation:
Department of General Surgery, Medical Faculty, Istanbul University, Turkey
S Tezelman
Affiliation:
Department of General Surgery, Medical Faculty, Istanbul University, Turkey
*
Address for correspondence: Dr Yesim Erbil, Department of General Surgery, Medical Faculty, Istanbul University, Istanbul 34093, Turkey. Fax: 90 212 5341605 E-mail: yerbil2003@yahoo.com
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Abstract

Purpose:

We aimed to evaluate the accuracy of ultrasonography, radioactive iodine uptake and serum thyroid-stimulating hormone level in predicting the volume of remnant thyroid gland.

Methods:

Sixty-six thyroidectomy patients were divided into two groups according to their functional status, i.e. those operated upon for nontoxic multinodular goitre (group one) and those operated upon for hyperthyroidism (group two). Ultrasonography, radioactive iodine uptake and thyroid-stimulating hormone assay were performed in all patients during the first post-operative month. The two groups were subdivided according to the amount of remnant thyroid volume detected on ultrasonography: <2 ml, 2–5 ml and >5 ml.

Results:

The remnant thyroid volume was positively correlated with the radioactive iodine uptake (rs = 0.684, p = 0.0001). The increase in remnant thyroid tissue radioactive iodine uptake was significantly greater in the patients operated upon for hyperthyroidism compared with those operated upon for nontoxic multinodular goitre (p = 0.0001). There was a negative correlation between remnant thyroid volume and post-operative serum thyroid-stimulating hormone level (rs =  −0.865, p = 0.0001) and between remnant thyroid tissue radioactive iodine uptake and post-operative serum thyroid-stimulating hormone level (rs = −0.682, p = 0.0001).

Conclusion:

Ultrasonography is a more accurate measure of remnant thyroid volume than radioactive iodine uptake in patients operated upon for hyperthyroidism, compared with those operated upon for nontoxic multinodular goitre.

Keywords

Thyroid GlandThyroid NeoplasmsThyroidectomyUltrasound
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 6 , June 2008 , pp. 615 - 622
Copyright
Copyright © JLO (1984) Limited 2007

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