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Chapter 8 - How to Optimize Treatment and What can Go Wrong?

Published online by Cambridge University Press:  22 May 2018

Dieter Schmidt ,
William O. Tatum  and
Steven Schachter
By
Dieter Schmidt
Dieter Schmidt
Affiliation:
Epilepsy Research Group, Free University of Berlin
William O. Tatum
Affiliation:
Department of Neurology, Beth Israel Deaconess Medical Center, Boston
Steven Schachter
Affiliation:
Department of Neurology, Beth Israel Deaconess Medical Center, Boston
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Common Pitfalls in Epilepsy
Case-Based Learning
 , pp. 140 - 155
Publisher: Cambridge University Press
Print publication year: 2018

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References

Beghi, E., Gatti, G., Tonini, C., et al. Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial. Epilepsy Res 2003;57: 1–13.Google Scholar
Brodie, M. J., Elder, A. T., Kwan, P. Epilepsy in later life. Lancet Neurol 2009;(11): 1019–30.CrossRefGoogle ScholarPubMed
Brodie, M. J., Overstall, P. W., Giorgi, L., the UK Lamotrigine Elderly Study Group. Multicentre, double-blind, randomised comparison between lamotrigine and carbamazepine in elderly patients with newly diagnosed epilepsy. Epilepsy Res 1999;37: 81–7.CrossRefGoogle ScholarPubMed
Elger, C. E., Schmidt, D. Modern management of epilepsy: a practical approach. Epilepsy Behav 2008;12(4): 501–39.Google Scholar
Fröscher, W., Eichelbaum, M., Gugler, R., Hildenbrand, G., Penin, H. A prospective randomized trial on the effect of monitoring plasma anticonvulsant levels in epilepsy. J Neurol 1981;224: 193–201.Google Scholar
Hakkarainen, H. Carbamazepine vs diphenylhydantoin vs their combination in adult epilepsy (abstract). Neurology 1980;30: 354.Google Scholar
Hermann, B., Seidenberg, M., Sager, M., et al. Growing old with epilepsy: the neglected issue of cognitive and brain health in aging and elder persons with chronic epilepsy. Epilepsia 2008;49(5): 731–40.Google Scholar
Hesdorffer, D. C., Hauser, W. A., Annegers, J. F., Kokmen, E., Rocca, W. A. Dementia and adult-onset unprovoked seizures. Neurology 1996 Mar; 46(3): 727–30.CrossRefGoogle ScholarPubMed
Jannuzzi, G., Cian, P., Fattore, C., et al. A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy. Epilepsia 2000;41: 222–30.Google Scholar
Kwan, P., Brodie, M. J. Early identification of refractory epilepsy. New Engl J Med 2000;342: 314–39.CrossRefGoogle ScholarPubMed
Kwan, P., Brodie, M. J. Effectiveness of first antiepileptic drug. Epilepsia 2001;42(10): 1255–60.CrossRefGoogle ScholarPubMed
Lempert, T., Bauer, M., Schmidt, D. Syncope: a videometric analysis of 56 episodes of transient cerebral hypoxia. Ann Neurol 1994;36: 233–7.Google Scholar
Meador, K. J. Effects of in utero antiepileptic drug exposure. Epilepsy Curr 2008;8(6): 143–7.Google Scholar
Morrow, J., Russell, A., Guthrie, E., et al. Malformation risks of antiepileptic drugs in pregnancy : a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry 2006;77: 193–8.Google Scholar
Patsalos, P. N., Berry, D. J., Bourgeois, B. F. D., et al. Antiepileptic drugs – best practice guidelines for therapeutic drug monitoring: a position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies. Epilepsia 2008;49: 1239–76.Google Scholar
Ramsay, R. E., Rowan, A. J., Pryor, F. M. Special considerations in treating the elderly patient with epilepsy. Neurology 2004;62: S24–9.Google Scholar
Ramsay, R. E., Uthman, B., Pryor, F. M., et al. Topiramate in older patients with partial-onset seizures: a pilot double-blind, dose-comparison study. Epilepsia 2008;49: 1180–5.CrossRefGoogle ScholarPubMed
Relling, M. V., Pui, C. H., Sandlund, J. T., et al. Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia. Lancet 2000 Jul 22; 356(9226): 285–90.Google Scholar
Rowan, A. J., Ramsay, R. E., Collins, J. F., et al. New onset geriatric epilepsy: a randomised study of gabapentin, lamotrigine and carbamazepine. Neurology 2005;64: 1868–73.CrossRefGoogle ScholarPubMed
Saetre, E., Perucca, E., Isojarvi, J., Gjerstad, L.; on behalf of the LAM 40089 Study Group. An international multicenter randomized double-blind controlled trial of lamotrigine and sustained-release carbamazepine in the treatment of newly diagnosed epilepsy. Epilepsia 2007 Jul; 48(7): 1292–302.Google Scholar
Schiller, Y., Najjar, Y. Quantifying the response to antiepileptic drugs: effect of past treatment history. Neurology 2008 Jan 1; 70(1): 54–65.CrossRefGoogle ScholarPubMed
Schmidt, D. Two antiepileptic drugs for intractable epilepsy with complex-partial seizures. J Neurol Neurosurg Psychiatry 1982;45(12): 1119–24.Google Scholar
Schmidt, D. Single drug therapy for intractable epilepsy. J Neurol 1983;229(4): 221–6.Google Scholar
Schmidt, D., Gram, L. Monotherapy versus polytherapy in epilepsy. CNS Drugs 1995;3: 194–208.Google Scholar
St. Louis, E. K. Monitoring antiepileptic drugs: a level-headed approach. Curr Neuropharmacol 2009;7: 115–19.Google Scholar
Tomson, T., Dahl, M. L., Kimland, E. Therapeutic monitoring of antiepileptic drugs for epilepsy. Cochrane Database Syst Rev 2007 Jan 24;(1): CD002216.Google ScholarPubMed

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