Book contents
- Multivariate Biomarker Discovery
- Multivariate Biomarker Discovery
- Copyright page
- Dedication
- Contents
- Preface
- Acknowledgments
- Part I Framework for Multivariate Biomarker Discovery
- Part II Regression Methods for Estimation
- Part III Classification Methods
- Part IV Biomarker Discovery via Multistage Signal Enhancement and Identification of Essential Patterns
- 14 Multistage Signal Enhancement
- 15 Essential Patterns, Essential Variables, and Interpretable Biomarkers
- Part V Multivariate Biomarker Discovery Studies
- References
- Index
14 - Multistage Signal Enhancement
from Part IV - Biomarker Discovery via Multistage Signal Enhancement and Identification of Essential Patterns
Published online by Cambridge University Press: 30 May 2024
- Multivariate Biomarker Discovery
- Multivariate Biomarker Discovery
- Copyright page
- Dedication
- Contents
- Preface
- Acknowledgments
- Part I Framework for Multivariate Biomarker Discovery
- Part II Regression Methods for Estimation
- Part III Classification Methods
- Part IV Biomarker Discovery via Multistage Signal Enhancement and Identification of Essential Patterns
- 14 Multistage Signal Enhancement
- 15 Essential Patterns, Essential Variables, and Interpretable Biomarkers
- Part V Multivariate Biomarker Discovery Studies
- References
- Index
Summary
Chapters 14 and 15 describe a method for the identification of parsimonious and robust multivariate biomarkers that may also have the best chance for plausible biological interpretation. The method is based on multistage signal enhancement and identification of essential patterns. Chapter 14 covers the first logical part of this method – the multistage signal enhancement approach leading to the identification of a pool of potentially important variables.
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- Multivariate Biomarker DiscoveryData Science Methods for Efficient Analysis of High-Dimensional Biomedical Data, pp. 209 - 212Publisher: Cambridge University PressPrint publication year: 2024