Book contents
- Frontmatter
- Dedication
- Contents
- List of insights
- Preface
- Notation
- Part I Preliminaries
- Part II Fundamentals of Biological Sequence Analysis
- Part III Genome-Scale Index Structures
- Part IV Genome-Scale Algorithms
- Part V Applications
- 14 Haplotype analysis
- 15 Pangenomics
- 16 Transcriptomics
- 17 Metagenomics
- References
- Index
17 - Metagenomics
from Part V - Applications
Published online by Cambridge University Press: 28 September 2023
- Frontmatter
- Dedication
- Contents
- List of insights
- Preface
- Notation
- Part I Preliminaries
- Part II Fundamentals of Biological Sequence Analysis
- Part III Genome-Scale Index Structures
- Part IV Genome-Scale Algorithms
- Part V Applications
- 14 Haplotype analysis
- 15 Pangenomics
- 16 Transcriptomics
- 17 Metagenomics
- References
- Index
Summary
Assume that a drop of seawater contains cells from many distinct species. Sequencing such a mixed sample and figuring out the relative abundancy of every species is a key problem in metagenomics. This chapter explores techniques for metagenomics analysis in different settings, for example with and without assuming that reference sequences are available. To solve these problems, we use techniques including tailored k-mer-based analyses, bidirectional BWT indexing, and network flows.
- Type
- Chapter
- Information
- Genome-Scale Algorithm DesignBioinformatics in the Era of High-Throughput Sequencing, pp. 394 - 413Publisher: Cambridge University PressPrint publication year: 2023