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Section 4 - Neurophysiology

Published online by Cambridge University Press:  31 July 2019

David Chambers ,
Christopher Huang  and
Gareth Matthews
David Chambers
Affiliation:
Salford Royal NHS Foundation Trust
Christopher Huang
Affiliation:
University of Cambridge
Gareth Matthews
Affiliation:
University of Cambridge
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Basic Physiology for Anaesthetists , pp. 189 - 278
Publisher: Cambridge University Press
Print publication year: 2019

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References

Further reading

Pannese, E.. Neurocytology: Fine Structure of Neurons, Nerve Processes and Neuroglial Cells, 2nd edition. Stuttgart, Thieme Publishing Group, 2016.Google Scholar

Further reading

Waxman, S.. Clinical Neuroanatomy, 28th edition. New York, McGraw-Hill Medical, 2017.Google Scholar
Hagihira, S.. Changes in the electroencephalogram during anaesthesia and their physiological basis. Br J Anaesth 2015; 115(Suppl. 1): i27–31.CrossRefGoogle ScholarPubMed
Raithatha, A., Pratt, G., Rash, A.. Developments in the management of acute ischaemic stroke: implications for anaesthetic and critical care management. Continuing Educ Anaesth Crit Care Pain 2013; 13(3): 80–6.Google Scholar
Avidan, M. S., Zhang, L., Burnside, B. A., et al. Anesthesia awareness and the bispectral index. N Engl J Med 2008; 358(11): 1097–108.CrossRefGoogle ScholarPubMed
Myles, P. S., Leslie, K., McNeil, J., et al. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial. Lancet 2004; 363(9423): 1757–63.Google Scholar
Macchi, C., Lova, R. M., Miniati, B., et al. The circle of Willis in healthy older persons. J Cardiovasc Surg (Torino) 2002; 43(6): 887–90.Google Scholar

Further reading

Irani, D. N.. Cerebrospinal Fluid in Clinical Practice. Philadelphia, Saunders, 2009.Google Scholar
Rekate, H. L.. The definition and classification of hydrocephalus: a personal recommendation to stimulate debate. Cerebrospinal Fluid Res 2008; 5: 2.Google Scholar

Further reading

Daneman, R., Prat, A.. The blood–brain barrier. Cold Spring Harb Perspect Biol 2015; 7(1): a020412.Google Scholar
Tajes, M., Ramos-Fernández, E., Weng-Jiang, X., et al. The blood–brain barrier: structure, function and therapeutic approaches to cross it. Mol Membr Biol 2014; 31(5): 152–67.CrossRefGoogle Scholar
Daneman, R.. The blood–brain barrier in health and disease. Ann Neurol 2012; 72(5): 648–72.CrossRefGoogle ScholarPubMed
Lawther, B. K., Kumar, S., Krovvindi, H.. Blood brain barrier. Continuing Educ Anaesth Crit Care Pain 2011; 11(4): 128–32.Google Scholar

Further reading

ter Laan, M., van Dijk, J. M. C., Elting, J. W. J., et al. Sympathetic regulation of cerebral blood flow in humans: a review. Br J Anaesth 2013; 111(3): 361–7.CrossRefGoogle ScholarPubMed
Ayata, C.. Spreading depression and neurovascular coupling. Stroke 2013; 44(6 Suppl. 1): S87–9.Google Scholar
Peterson, E. C., Wang, Z., Britz, G.. Regulation of cerebral blood flow. Int J Vasc Med 2011; 2011: 823525.Google ScholarPubMed

Further reading

Wiles, M. D.. Blood pressure in trauma resuscitation: ‘pop the clot’ vs. ‘drain the brain’? Anaesthesia 2017; 72(12): 1448–55.Google Scholar
Protheroe, R. T., Gwinnutt, C. L.. Early hospital care of severe traumatic brain injury. Anaesthesia 2011; 66(11): 1035–47.CrossRefGoogle ScholarPubMed
Pattinson, K., Wynne-Jones, G., Imray, C. H. E.. Monitoring intracranial pressure, perfusion and metabolism. Continuing Educ Anaesth Crit Care Pain 2005; 5(4): 130–3.CrossRefGoogle Scholar

Further reading

Kiernan, J. A., Rajakumar, R.. Barr’s The Human Nervous System: An Anatomical Viewpoint, 10th edition. Philadelphia, Lippincott Williams & Wilkins, 2013.Google Scholar
Martin, J. H.. Neuroanatomy Text and Atlas, 4th edition. New York, McGraw-Hill Medical, 2012.Google Scholar
Hadjipavlou, G., Cortese, A. M., Ramaswamy, B.. Spinal cord injury and chronic pain. BJA Education 2016; 16(8): 264–8Google Scholar
Denton, M., McKinlay, J.. Cervical cord injury and critical care. Continuing Educ Anaesth Crit Care Pain 2009; 9(3): 82–6.Google Scholar
Šedy, J., Zicha, J., Kuneš, J., et al. Mechanisms of neurogenic pulmonary edema development. Physiol Res 2008; 57: 499–506.CrossRefGoogle ScholarPubMed
Veale, P., Lamb, J.. Anaesthesia and acute spinal cord injury. Continuing Educ Anaesth Crit Care Pain 2002; 2(5): 139–43.CrossRefGoogle Scholar

Further reading

Keynes, R. D., Aidley, D. J., Huang, C. L.-H.. Nerve and Muscle, 4th edition. Cambridge, Cambridge University Press, 2011.Google Scholar
Wright, S. H.. Generation of resting membrane potential. Adv Physiol Educ 2004; 28: 139–42.Google Scholar

Further reading

Keynes, R. D., Aidley, D. J., Huang, C. L.-H.. Nerve and Muscle, 4th edition. Cambridge, Cambridge University Press, 2011.Google Scholar
Scholz, A.. Mechanisms of (local) anaesthetics on voltage-gated sodium and other ion channels. Br J Anaesth 2002; 89(1): 52–61.CrossRefGoogle ScholarPubMed

Further reading

Hunter, J. M.. Reversal of residual neuromuscular block: complications associated with perioperative management of muscle relaxation. Br J Anaesth 2017; 119(Suppl. 1): i53–62.Google Scholar
Thevathasan, T., Shih, S. L., Safari, K. C., et al. Association between intraoperative non-depolarising neuromuscular blocking agent dose and 30-day readmission after abdominal surgery. Br J Anaesth 2017; 119(4): 595–605.CrossRefGoogle ScholarPubMed
Naguib, M., Brull, S. J., Johnson, K. B.. Conceptual and technical insights into the basis of neuromuscular monitoring. Anaesthesia 2017; 72(Suppl. 1): 16–37.Google Scholar
Khirwadkar, R., Hunter, J. M.. Neuromuscular physiology and pharmacology: an update. Continuing Educ Anaesth Crit Care Pain 2012; 12(5): 237–44.Google Scholar
Weir, C. J.. The molecular mechanisms of general anaesthesia: dissecting the GABAA receptor. Continuing Educ Anaesth Crit Care Pain 2006; 6(2): 49–53.Google Scholar
Thavasothy, M., Hirsch, N.. Myasthena gravis. Continuing Educ Anaesth Crit Care Pain 2002; 2(3): 88–90.Google Scholar

Further reading

Xiao, J.. Muscle Atrophy. Singapore, Springer Verlag, 2018.CrossRefGoogle Scholar
Keynes, R. D., Aidley, D. J., Huang, C. L.-H.. Nerve and Muscle, 4th edition. Cambridge, Cambridge University Press, 2011.CrossRefGoogle Scholar
Gupta, P. K., Hopkins, P. M.. Diagnosis and management of malignant hyperthermia. BJA Education 2017; 17(7): 249–54.CrossRefGoogle Scholar
Huang, C. L.-H., Pedersen, T. H., Fraser, J. A.. Reciprocal dihydropyridine and ryanodine receptor interactions in skeletal muscle activation. J Muscle Res Cell Motil 2011; 32(3): 171–202.Google Scholar
Appleton, R., Kinsella, J.. Intensive care unit-acquired weakness. Continuing Educ Anaesth Crit Care Pain 2012; 12(2): 62–6.Google Scholar
Marsh, S., Ross, N., Pittard, A.. Neuromuscular disorders and anaesthesia. Part 1: generic anaesthetic management. Continuing Educ Anaesth Crit Care Pain 2011; 11(4): 115–18.Google Scholar
Marsh, S., Pittard, A.. Neuromuscular disorders and anaesthesia. Part 2: specific neuromuscular disorders. Continuing Educ Anaesth Crit Care Pain 2011; 11(4): 119–23.Google Scholar

Further reading

Proske, U., Gandevia, S. C.. The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force. Physiol Rev 2012; 92(4): 1651–97.CrossRefGoogle ScholarPubMed

Further reading

Keynes, R. D., Aidley, D. J., Huang, C. L.-H.. Nerve and Muscle, 4th edition. Cambridge, Cambridge University Press, 2011.CrossRefGoogle Scholar
Sanders, K. M.. Regulation of smooth muscle excitation and contraction. Neurogastroneterol Motil 2008; 20(Suppl. 1): 39–53.Google Scholar

Further reading

Keynes, R. D., Aidley, D. J., Huang, C. L.-H.. Nerve and Muscle, 4th edition. Cambridge, Cambridge University Press, 2011.CrossRefGoogle Scholar
Litonius, E., Tarkkila, P., Neuvonen, P. J., et al. Effect of intravenous lipid emulsion on bupivacaine plasma concentration in humans. Anaesthesia 2012; 67(6): 600–5.CrossRefGoogle ScholarPubMed
Stone, M. E., Salter, B., Fischer, A.. Perioperative management of patients with cardiac implantable electronic devices. Br J Anaesth 2011; 107(Suppl. 1): i16–26.Google Scholar
AAGBI Safety Guideline. Management of Severe Local Anaesthetic Toxicity, Association of Anaesthetists of Great Britain and Ireland, 2010; www.aagbi.org/sites/default/files/la_toxicity_2010_0.pdf.Google Scholar
Pinnell, J., Turner, S., Howell, S.. Cardiac muscle physiology. Continuing Educ Anaesth Crit Care Pain 2007; 7(3): 85–8.CrossRefGoogle Scholar
Dippenaar, J. M.. Local anaesthetic toxicity. S Afr J Anaesth Analges 2007; 13(3): 23–8.Google Scholar
Rohr, S.. Role of gap junctions in the propagation of the cardiac action potential. Cardiovasc Res 2004; 62(2): 309–22.Google Scholar
Morgan-Hughes, N. J., Hood, G.. Anaesthesia for a patient with a cardiac transplant. Continuing Educ Anaesth Crit Care Pain 2002; 2(3): 74–8.CrossRefGoogle Scholar
Vaughan, E.. Williams classification of antidysrhythmic drugs. Pharmacol Ther B 1975; 1: 115–38.Google Scholar
Singh, B.. Beta-blockers and calcium channel blockers as anti-arrhythmic drugs. In: Zipes, D., Jalife, J.. Cardiac Electrophysiology from Cell to Bedside. Philadelphia: Saunders, 2004; 918–31.Google Scholar

Further reading

Kusumoto, F.. ECG Interpretation: From Pathophysiology to Clinical Application. Berlin, Springer, 2009.CrossRefGoogle Scholar
Das, M. K., Zipes, D. P.. Electrocardiography of Arrhythmias: A Comprehensive Review. New York, Elsevier, 2012.Google Scholar

Further reading

Robertson, D., Biaggioni, I., Burnstock, G., Low, P. A., Paton, J. F. R.. Primer on the Autonomic Nervous System. Cambridge, MA, Academic Press, 2012.Google Scholar
Andreae, M. H., Andreae, D. A.. Regional anaesthesia to prevent chronic pain after surgery: a Cochrane systematic review and meta-analysis. Br J Anaesth 2013; 111(5): 711–20.CrossRefGoogle ScholarPubMed
McDonnell, J. G., Finnerty, O., Laffey, J. G.. Stellate ganglion blockade for analgesia following upper limb surgery. Anaesthesia 2011; 66(7): 611–14.Google Scholar
Menon, R., Swanepoel, A.. Sympathetic blocks. Continuing Educ Anaesth Crit Care Pain 2010; 10(3): 88–92.CrossRefGoogle Scholar

Further reading

Moller, A. R.. Pain: Its Anatomy, Physiology and Treatment. Dallas, Moller Publishing, 2014.Google Scholar
Brook, P., Pickering, T., Connell, J.. Oxford Handbook of Pain Management. Oxford, Oxford University Press, 2011.Google Scholar
Albrecht, E., Kirkham, K. R., Liu, S. S., et al. Perioperative intravenous administration of magnesium sulphate and postoperative pain: a meta-analysis. Anaesthesia 2013; 68(1): 79–90.Google Scholar
Sandkühler, J.. Models and mechanisms of hyperalgesia and allodynia. Physiol Rev 2009; 89(2): 707–58.Google Scholar
D’Mello, R., Dickenson, A. H.. Spinal cord mechanisms of pain. Br J Anaesth 2008; 101(1): 8–16.CrossRefGoogle ScholarPubMed

Further reading

Kaufman, P. L., Alm, A., Levin, L. A., et al. Adler’s Physiology of the eye, 11th edition. Philadelphia, Saunders Elsevier, 2011.Google Scholar
Murgatroyd, H., Bembridge, J.. Intraocular pressure. Continuing Educ Anaesth Crit Care Pain 2008; 8(3): 100–3.Google Scholar
Roth, S.. Perioperative visual loss: what do we know, what can we do? Br J Anaesth 2009; 103(Suppl. 1): i31–40.CrossRefGoogle Scholar

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