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Chapter 50 - Preterm Labour

from Section 5 - Intrapartum Care

Published online by Cambridge University Press:  20 November 2021

By
William C. Maina
Edited by
Tahir Mahmood ,
Charles Savona Ventura ,
Ioannis Messinis  and
Sambit Mukhopadhyay
Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Preterm birth represents the single largest cause of morbidity and mortality for newborns and a major cause of morbidity for pregnant women. It affects about 9% of births in high-income countries and an estimated 13% of births in low- and middle-income countries. Babies born preterm have high rates of early, late and post-neonatal mortality, and the risk of mortality increases as gestational age at birth decreases. Babies who survive have increased rates of disability.

Type
Chapter
Information
The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
Obstetrics & Maternal-Fetal Medicine
 , pp. 409 - 413
Publisher: Cambridge University Press
Print publication year: 2021

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References

NICE. Preterm Labour and Birth. Guideline 25. November 2015. www.nice.org.uk/guidance/ng25.Google Scholar
Watts, DH, Krohn, MA, Hillier, SL, Eschenbach, DA. The association of occult fluid infection with gestational age and neonatal outcome among women in preterm labour. Obstet Gynecol. 1992;79:351–7.CrossRefGoogle Scholar
Salafia, CM, Vogel, CA, Vintzileos, AM, et al. Placental pathologic findings in preterm birth. Am J Obstet Gynecol. 1991;165:934–8.CrossRefGoogle ScholarPubMed
Gibbs, W, Challis, JRG. Mechanism of term and preterm birth. J Obstet Gynaecol Can. 2002;24(11):874–83.Google Scholar
Schmitz, T, Kayem, G, Maillard, F, et al. Selective use of sonographic cervical length measurement for predicting imminent preterm delivery in women with preterm labour and intact membranes. Ultrasound Obstet Gynecol. 2008 Apr;31(4): 421–6.CrossRefGoogle ScholarPubMed
Tsoi, E, Fuchs, IB, Rane, S, Geerts, L, Nicolaides, KH. Sonographic measurement of cervical length in threatened preterm labour in singleton pregnancies with intact membranes. Ultrasound Obstet Gynecol. 2005;25:353–6.Google Scholar
Roberts, D, Brown, J, Medley, N, Dalziel, SR. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev. 2017 Mar 21;(3):CD004454.Google Scholar
Crowther, CA, MacKinlay, CJD, Middleton, P, Harding, JE. Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes. Cochrane Database Syst Rev. 2015 Jul 5;(7):CD003935.Google Scholar
Doyle, LW, Crowther, CA, Middleton, P, Marret, S, Rouse, D. Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus. Cochrane Database Syst Rev. 2009. Jan 21;(1):CD004661.Google ScholarPubMed
Costantine, MM, Weiner, SJ, Eunice Kennedy, Shriver; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Effects of antenatal exposure to magnesium sulfate on neuroprotection and mortality in preterm infants: a meta-analysis.Obstet Gynecol. 2009;114:354–64.Google Scholar
Prevention of Early-Onset Neonatal Group-B Streptococcal Disease, Green-top Guideline No 36. London: Royal College of Obstetricians and Gynaecologists, 2017.Google Scholar
Alfirevic, Z, Stampalija, T, Medley, N. Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. Cochrane Database Syst Rev. 2017 Jun 6;(6):CD008991Google Scholar
Su, L-L, Samuel, M, Chong, Y-S. Progestational agents for treating threatened or established preterm labour. Cochrane Database Syst Rev. 2014. Jan 20;(1):CD006770.Google ScholarPubMed
Norman, JE, Marlow, N, Messow, CM, et al. Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial. Lancet. 2016 May 21;387(10033):2106–16.CrossRefGoogle ScholarPubMed

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