Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- Psychology, health and illness
- Medical topics
- Abortion
- Accidents and unintentional injuries
- Acne
- Alcohol abuse
- Allergies to drugs
- Allergies to food
- Allergies: general
- Amnesia
- Amputation and phantom limb pain
- Anaesthesia and psychology
- Antenatal care
- Aphasia recovery, treatment and psychosocial adjustment
- Asthma
- Back pain
- Blindness and visual disability
- Blood donation
- Breastfeeding
- Burn injuries: psychological and social aspects
- Cancer: breast
- Cancers of the digestive tract
- Cancer: general
- Cancer: gynaecologic
- Cancer: head and neck
- Cancer: Hodgkin's and non-Hodgkin's lymphoma
- Cancer: leukaemia
- Cancer: lung
- Cancer: prostate
- Cancer: skin
- Carotid artery disease and treatment
- Chemotherapy
- Child abuse and neglect
- Chromosomal abnormalities
- Chronic fatigue syndrome
- Chronic obstructive pulmonary disease (COPD): chronic bronchitis and emphysema
- Cleft lip and palate
- Cold, common
- Complementary medicine
- Contraception
- Coronary heart disease: impact
- Coronary heart disease: cardiac psychology
- Coronary heart disease: heart failure
- Coronary heart disease: rehabilitation
- Coronary heart disease: surgery
- Cystic fibrosis
- Acquired hearing loss
- Dementias
- Diabetes mellitus
- Domestic violence, intimate partner violence and wife battering
- Drug dependency: benzodiazepines
- Drug dependence: opiates and stimulants
- Drugs: beta-blockers
- Drugs: psychotropic medication
- Dyslexia
- Eating disorders
- Eczema
- Endocrine disorders
- Enuresis
- Epilepsy
- Epstein–Barr virus infection
- Facial disfigurement and dysmorphology
- Fetal wellbeing: monitoring and assessment
- Gastric and duodenal ulcers
- Growth retardation
- Haemophilia
- Head injury
- Headache and migraine
- Herpes
- HIV/AIDS
- Hormone replacement therapy
- Hospital acquired infection
- Huntington's disease
- Hyperactivity
- Hypertension
- Hyperthyroidism
- Hyperventilation
- Hysterectomy
- Immunization
- Incontinence
- Infertility
- Inflammatory bowel disease
- Intensive care unit
- Intimate examinations
- Irritable bowel syndrome
- Lymphoedema
- Malaria
- Mastalgia (breast pain)
- Meningitis
- Menopause and postmenopause
- MMR vaccine
- Motor neurone disease
- Multiple sclerosis
- Myasthenia gravis
- Neurofibromatosis
- Non-cardiac chest pain
- Obesity
- Oral care and hygiene
- Osteoarthritis
- Osteoporosis
- Parkinson's disease
- Pelvic pain
- Post-traumatic stress disorder
- Postnatal depression
- Pregnancy and childbirth
- Premature babies
- Premenstrual syndrome
- Psoriasis
- Radiotherapy
- Rape and sexual assault
- Reconstructive and cosmetic surgery
- Renal failure, dialysis and transplantation
- Repetitive strain injury
- Rheumatoid arthritis
- Road traffic accidents: human factors
- Screening: antenatal
- Screening: cancer
- Screening: cardiac
- Screening: genetic
- Self-examination: breasts, testicles
- Sexual dysfunction
- Sexually transmitted infections
- Sickle cell disease
- Skin disorders
- Sleep apnoea
- Sleep disorders
- Spina bifida
- Spinal cord injury
- Sterilization and vasectomy
- Stroke
- Stuttering
- Suicide
- Tinnitus
- Tobacco use
- Toxins: environmental
- Transplantation
- Urinary tract symptoms
- Vertigo and dizziness
- Vision disorders
- Voice disorders
- Volatile substance abuse
- Vomiting and nausea
- Index
- References
Immunization
from Medical topics
Published online by Cambridge University Press: 18 December 2014
- Frontmatter
- Contents
- List of contributors
- Preface
- Psychology, health and illness
- Medical topics
- Abortion
- Accidents and unintentional injuries
- Acne
- Alcohol abuse
- Allergies to drugs
- Allergies to food
- Allergies: general
- Amnesia
- Amputation and phantom limb pain
- Anaesthesia and psychology
- Antenatal care
- Aphasia recovery, treatment and psychosocial adjustment
- Asthma
- Back pain
- Blindness and visual disability
- Blood donation
- Breastfeeding
- Burn injuries: psychological and social aspects
- Cancer: breast
- Cancers of the digestive tract
- Cancer: general
- Cancer: gynaecologic
- Cancer: head and neck
- Cancer: Hodgkin's and non-Hodgkin's lymphoma
- Cancer: leukaemia
- Cancer: lung
- Cancer: prostate
- Cancer: skin
- Carotid artery disease and treatment
- Chemotherapy
- Child abuse and neglect
- Chromosomal abnormalities
- Chronic fatigue syndrome
- Chronic obstructive pulmonary disease (COPD): chronic bronchitis and emphysema
- Cleft lip and palate
- Cold, common
- Complementary medicine
- Contraception
- Coronary heart disease: impact
- Coronary heart disease: cardiac psychology
- Coronary heart disease: heart failure
- Coronary heart disease: rehabilitation
- Coronary heart disease: surgery
- Cystic fibrosis
- Acquired hearing loss
- Dementias
- Diabetes mellitus
- Domestic violence, intimate partner violence and wife battering
- Drug dependency: benzodiazepines
- Drug dependence: opiates and stimulants
- Drugs: beta-blockers
- Drugs: psychotropic medication
- Dyslexia
- Eating disorders
- Eczema
- Endocrine disorders
- Enuresis
- Epilepsy
- Epstein–Barr virus infection
- Facial disfigurement and dysmorphology
- Fetal wellbeing: monitoring and assessment
- Gastric and duodenal ulcers
- Growth retardation
- Haemophilia
- Head injury
- Headache and migraine
- Herpes
- HIV/AIDS
- Hormone replacement therapy
- Hospital acquired infection
- Huntington's disease
- Hyperactivity
- Hypertension
- Hyperthyroidism
- Hyperventilation
- Hysterectomy
- Immunization
- Incontinence
- Infertility
- Inflammatory bowel disease
- Intensive care unit
- Intimate examinations
- Irritable bowel syndrome
- Lymphoedema
- Malaria
- Mastalgia (breast pain)
- Meningitis
- Menopause and postmenopause
- MMR vaccine
- Motor neurone disease
- Multiple sclerosis
- Myasthenia gravis
- Neurofibromatosis
- Non-cardiac chest pain
- Obesity
- Oral care and hygiene
- Osteoarthritis
- Osteoporosis
- Parkinson's disease
- Pelvic pain
- Post-traumatic stress disorder
- Postnatal depression
- Pregnancy and childbirth
- Premature babies
- Premenstrual syndrome
- Psoriasis
- Radiotherapy
- Rape and sexual assault
- Reconstructive and cosmetic surgery
- Renal failure, dialysis and transplantation
- Repetitive strain injury
- Rheumatoid arthritis
- Road traffic accidents: human factors
- Screening: antenatal
- Screening: cancer
- Screening: cardiac
- Screening: genetic
- Self-examination: breasts, testicles
- Sexual dysfunction
- Sexually transmitted infections
- Sickle cell disease
- Skin disorders
- Sleep apnoea
- Sleep disorders
- Spina bifida
- Spinal cord injury
- Sterilization and vasectomy
- Stroke
- Stuttering
- Suicide
- Tinnitus
- Tobacco use
- Toxins: environmental
- Transplantation
- Urinary tract symptoms
- Vertigo and dizziness
- Vision disorders
- Voice disorders
- Volatile substance abuse
- Vomiting and nausea
- Index
- References
Summary
Overview
Immunization is designed to stimulate immune responses against antigens of infectious agents (e.g. bacteria or viruses) and generate specific immunological memory such that successfully immunized individuals, when exposed to the infectious agent later in life, will respond with protective immunity. When this response was first being elucidated, the cellular and molecular interactions involving T and B lymphocytes (main cells of the immune system), antibodies (antigen-specific effector molecules) and cytokines (immune regulatory hormones) were thought to operate virtually autonomously within the body, influenced predominantly by the internal state of the immune network and the characteristics of antigens (foreign shapes derived from infectious agents). However, individual differences in susceptibility to infection and effectiveness of immunity following vaccination, led to exploration of non-physiological factors.
Research using laboratory animals demonstrated that ‘lifestyle’ factors such as overcrowding (Edwards & Dean, 1977) and exposure to physically stressful conditions (Sheridan, 1998) reduced immune responses to immunization often to the point that the animals become susceptible to infection. Such studies extended into the human arena have confirmed that many aspects of human psychology affect immune responses to vaccination and should be considered as significant factors in vaccine effectiveness.
Research evidence
Stress and immunization
When healthy women were immunized with a novel antigen, keyhole limpet haemocyanin (KLH), those reporting more stressful events had lower baseline and post-immunization lymphocyte proliferation (Snyder et al., 1993) and anti-KLH antibody levels in their blood, while those reporting more social support had higher responses (Snyder et al., 1990; Snyder et al., 1993).
- Type
- Chapter
- Information
- Cambridge Handbook of Psychology, Health and Medicine , pp. 751 - 754Publisher: Cambridge University PressPrint publication year: 2007