Book contents
- Frontmatter
- Contents
- Preface
- Acknowledgments
- Prologue
- Introduction
- 1 The Case of Black Sweat
- 2 A Case of Hives That Wouldn't Go Away
- 3 The Painful Bath
- 4 A Shower of Hives
- 5 A Premenstrual Rash
- 6 Uncombable Hair
- 7 The Man Who Couldn't Sweat
- 8 Scratch Blisters
- 9 Skin Deep Photography
- 10 The Bug That Never Was
- 11 Blue Spots
- 12 White Spots
- 13 Same Place, Next Time Rash
- 14 The Brown Spots That Wouldn't Go Away
- 15 The Case of the Painful Fingertips
- 16 A Strange Sunburn
- 17 A Multiple Personality Dermatitis
- 18 Accidental Hives
- 19 Rotten Fish Odor
- 20 Hormone Blisters
- 21 Flower Shop Itch
- 22 “Stress and a Penny” Hives
- 23 The Case of Unilateral Wrinkles
- 24 Fiery Red Legs
- 25 Painful Feet
- 26 Hot Flashes and Cold Cream
- 27 The Blisters and the Skin Test
- 28 A Chilling Pain
- 29 Rough Skin and Sore Throats
- 30 The Premenstrual Purple Chin
- 31 Nine Year Hives
- 32 Golf Course Dermatitis
- 33 The Secret Message
- 34 Herpes Gladiatorum
- 35 Sunshine Allergy
- 36 L'homme Rouge
- 37 Rings of Rash
- 38 The Breasts That Never Stopped Growing
- 39 The Minister's Hives
- 40 Hardened Skin
- 41 Battery Blisters
- 42 Swollen Lips
- 43 The Worm from Outer Space
- 44 A New Light on Psoriasis
- 45 Black and Blue Spots
- 46 The Emergency Room Itch
- 47 The Sleeper
- 48 A Crazy Rash
- 49 Bald Spots
- 50 The Dog Died
- 51 The Abacus Tumor
- 52 No Spit
- 53 The Smell of Burnt Toast
- 54 The Twenty-Three Year Itch
- 55 The Mysterious Treatment
- 56 The Creeping Acne Cyst
- 57 Our First Case
- 58 A Strange Case of Acne
- 59 The Case of the Glass Eye
- 60 The Hand Eczema Caper
- 61 The Sore That Would Never Heal
- 62 Black Blisters
- References
- Index
5 - A Premenstrual Rash
Published online by Cambridge University Press: 23 November 2009
- Frontmatter
- Contents
- Preface
- Acknowledgments
- Prologue
- Introduction
- 1 The Case of Black Sweat
- 2 A Case of Hives That Wouldn't Go Away
- 3 The Painful Bath
- 4 A Shower of Hives
- 5 A Premenstrual Rash
- 6 Uncombable Hair
- 7 The Man Who Couldn't Sweat
- 8 Scratch Blisters
- 9 Skin Deep Photography
- 10 The Bug That Never Was
- 11 Blue Spots
- 12 White Spots
- 13 Same Place, Next Time Rash
- 14 The Brown Spots That Wouldn't Go Away
- 15 The Case of the Painful Fingertips
- 16 A Strange Sunburn
- 17 A Multiple Personality Dermatitis
- 18 Accidental Hives
- 19 Rotten Fish Odor
- 20 Hormone Blisters
- 21 Flower Shop Itch
- 22 “Stress and a Penny” Hives
- 23 The Case of Unilateral Wrinkles
- 24 Fiery Red Legs
- 25 Painful Feet
- 26 Hot Flashes and Cold Cream
- 27 The Blisters and the Skin Test
- 28 A Chilling Pain
- 29 Rough Skin and Sore Throats
- 30 The Premenstrual Purple Chin
- 31 Nine Year Hives
- 32 Golf Course Dermatitis
- 33 The Secret Message
- 34 Herpes Gladiatorum
- 35 Sunshine Allergy
- 36 L'homme Rouge
- 37 Rings of Rash
- 38 The Breasts That Never Stopped Growing
- 39 The Minister's Hives
- 40 Hardened Skin
- 41 Battery Blisters
- 42 Swollen Lips
- 43 The Worm from Outer Space
- 44 A New Light on Psoriasis
- 45 Black and Blue Spots
- 46 The Emergency Room Itch
- 47 The Sleeper
- 48 A Crazy Rash
- 49 Bald Spots
- 50 The Dog Died
- 51 The Abacus Tumor
- 52 No Spit
- 53 The Smell of Burnt Toast
- 54 The Twenty-Three Year Itch
- 55 The Mysterious Treatment
- 56 The Creeping Acne Cyst
- 57 Our First Case
- 58 A Strange Case of Acne
- 59 The Case of the Glass Eye
- 60 The Hand Eczema Caper
- 61 The Sore That Would Never Heal
- 62 Black Blisters
- References
- Index
Summary
“My complexion is awful” was the complaint of a thirty-four-year-old woman. She had been referred to us for treatment of a facial rash, which had resisted the therapies of a half dozen doctors over the past thirteen years. Several biopsies had been done with the principal finding being intense inflammatory changes around the blood vessels.
Upon examining her, we saw redness, acne-like pimples, some small blisters, and yellow crusts on her face. Her problem had defied not only therapy, but also classification. It wasn't exactly rosacea or acne. We were puzzled, but intensive questioning opened a door of understanding. We asked, “Does it get worse before your menstrual period?” Her answer was, “I have no idea – it's worse all the time.” But several visits later she came in saying, “You know, it really does get worse before my period! I had never noticed that and you are the first doctor to ask me.” We now suspected she was allergic to her own ovarian hormone, progesterone.
Years before we had demonstrated that women could become sensitive to their own progesterone. This hormone can induce a variety of skin changes, including itching, hives, and even water blisters. The clue to progesterone sensitivity is the observation that the problem is always worse just before the period – the time when the highest blood levels of progesterone are found. Once the menses are over, progesterone levels drop and the skin reaction abates.
- Type
- Chapter
- Information
- Consultations in DermatologyStudies of Orphan and Unique Patients, pp. 23 - 25Publisher: Cambridge University PressPrint publication year: 2006