Book contents
- Frontmatter
- Contents
- List of plates
- Preface
- Acknowledgements
- SECTION 1 INDIVIDUAL VIRUSES
- Introduction to virology
- 1 Adenoviruses
- 2 Arboviruses and haemorrhagic fever viruses
- 3 Cytomegalovirus (CMV)
- 4 Epstein–Barr virus (EBV)
- 5 Enteroviruses
- 6 Hepatitis A virus (HAV)
- 7 Hepatitis B and D viruses (HBV and HDV)
- 8 Hepatitis C virus (HCV)
- 9 Hepatitis E virus (HEV)
- 10 Herpes simplex virus (HSV)
- 11 Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)
- 12 Human herpes viruses types 6, 7 and 8 (HHV 6, 7 and 8)
- 13 Human T-cell leukaemia virus (HTLV)
- 14 Influenza viruses
- 15 Measles virus
- 16 Mumps virus
- 17 Noroviruses
- 18 Parainfluenza viruses
- 19 Papilloma and polyoma viruses
- 20 Parvovirus B19
- 21 Pox viruses
- 22 Rabies virus
- 23 Respiratory syncytial virus (RSV)
- 24 Rhinoviruses
- 25 Rotavirus
- 26 Rubella virus
- 27 SARS CoV and other coronaviruses
- 28 Varicella-zoster virus (VZV)
- SECTION 2 OTHER RELATED AGENTS
- SECTION 3 CLINICAL SYNDROMES
- SECTION 4 DIAGNOSTIC TECHNIQUES
- SECTION 5 PATIENT MANAGEMENT
- Index
- Plate section
25 - Rotavirus
Published online by Cambridge University Press: 07 December 2009
- Frontmatter
- Contents
- List of plates
- Preface
- Acknowledgements
- SECTION 1 INDIVIDUAL VIRUSES
- Introduction to virology
- 1 Adenoviruses
- 2 Arboviruses and haemorrhagic fever viruses
- 3 Cytomegalovirus (CMV)
- 4 Epstein–Barr virus (EBV)
- 5 Enteroviruses
- 6 Hepatitis A virus (HAV)
- 7 Hepatitis B and D viruses (HBV and HDV)
- 8 Hepatitis C virus (HCV)
- 9 Hepatitis E virus (HEV)
- 10 Herpes simplex virus (HSV)
- 11 Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)
- 12 Human herpes viruses types 6, 7 and 8 (HHV 6, 7 and 8)
- 13 Human T-cell leukaemia virus (HTLV)
- 14 Influenza viruses
- 15 Measles virus
- 16 Mumps virus
- 17 Noroviruses
- 18 Parainfluenza viruses
- 19 Papilloma and polyoma viruses
- 20 Parvovirus B19
- 21 Pox viruses
- 22 Rabies virus
- 23 Respiratory syncytial virus (RSV)
- 24 Rhinoviruses
- 25 Rotavirus
- 26 Rubella virus
- 27 SARS CoV and other coronaviruses
- 28 Varicella-zoster virus (VZV)
- SECTION 2 OTHER RELATED AGENTS
- SECTION 3 CLINICAL SYNDROMES
- SECTION 4 DIAGNOSTIC TECHNIQUES
- SECTION 5 PATIENT MANAGEMENT
- Index
- Plate section
Summary
The virus
Rotavirus is a double-stranded RNA virus belonging to the family Reoviridae. It is called rotavirus because by electron microscopy the virus particle resembles a wheel (see Fig. 25.1).
Epidemiology
Route of spread
Rotavirus spreads among humans by the faecal–oral and respiratory routes. There are seven different groups (A–G). Group A rotaviruses are the major cause of human infection, but groups B and C also infect humans. Rotavirus infections occur in most animal species, and although they can infect humans, are mostly associated with mild or no human disease, and no onward transmission.
Prevalence
Rotavirus infections are common in childhood and have a high morbidity with associated mortality in poor developing countries. In the UK, by the age of 5 years 90% of children have been infected. Reinfection can occur throughout life, but only the first infection after loss of maternal protection is associated with severe symptoms, and reinfections in older children and adults tend to be mild or asymptomatic. Infection usually occurs between November and March.
Incubation period
The incubation period of rotavirus is 1–2 days.
Infectious period
Patients are most infectious when symptomatic with diarrhoea and vomiting.
- Type
- Chapter
- Information
- Clinical and Diagnostic Virology , pp. 106 - 108Publisher: Cambridge University PressPrint publication year: 2009