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12 - Beyond DNA

from PART IV - The final frontier

Published online by Cambridge University Press:  16 March 2010

Susan Aldridge
Affiliation:
Clinical Sciences Centre, London
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Summary

The knowledge of the structure and function of DNA is probably the most powerful concept in biology, standing, as it does, at the very heart of our understanding of inheritance, and co-ordination of the biochemical activity of the cell. For some scientists, the molecular approach to the science of life–with DNA as the master molecule – provides a comprehensive understanding of nature. Unsolved problems such as the nature of human consciousness or how an embryo develops will be clarified as soon as the appropriate genes are cloned – they say. Others argue that molecular genetics is only part of a far larger picture and that other theories and ideas are equally worthy of attention and further exploration.

Neo-Darwinism and the selfish gene

Neo-Darwinism, as a theory, is not as modern as it sounds. The term was first coined in 1896, and refers to the synthesis of the work of Darwin with that of Mendel. Just to recap, Darwin's observations of nature led him to propose that variation of phenotype within species occurred, and the variants that were best adapted to the environment would leave more offspring (‘the survival of the fittest’). Thus, life evolved through the generations. Mendel took one step further towards a mechanism for inheritance with his experimental discovery of genes as being discrete inheritable entities.

The discovery of the self-replication of DNA, and of gene mutations that were transmitted from cell to cell, and through the generations, provided a powerful explanation for both Darwin's and Mendel's theories at a fundamental molecular level. Genes are stretches of DNA.

Type
Chapter
Information
The Thread of Life
The Story of Genes and Genetic Engineering
, pp. 243 - 252
Publisher: Cambridge University Press
Print publication year: 1996

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  • Beyond DNA
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.013
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  • Beyond DNA
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.013
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Beyond DNA
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.013
Available formats
×