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Chapter E2 - Two-dimensional IR spectroscopy

from Part E - Optical spectroscopy

Published online by Cambridge University Press:  05 November 2012

Igor N. Serdyuk ,
Nathan R. Zaccai  and
Joseph Zaccai
Igor N. Serdyuk
Affiliation:
Institute of Protein Research, Moscow
Nathan R. Zaccai
Affiliation:
University of Bristol
Joseph Zaccai
Affiliation:
Institut de Biologie Structurale, Grenoble
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Summary

The present chapter is included in Part E with the other optical spectroscopy methods; however, the development of two-dimensional IR (2D-IR) spectroscopy is strongly based on two-dimensional NMR, and it is easier to understand after reading the relevant sections in Part J, which the reader is strongly encouraged to do first.

Historical review and introduction to biological problems

1950

O. Hann proposed coherent spectroscopy – the use of radiation fields with well-defined phase properties – to extract information about atoms and molecules. The ‘spin echo’ experiment in nuclear magnetic resonance was the first demonstration of the possibilities of coherent spectroscopy.

1957

R. P. Feynman, F. L. Vernon Jr. and R. W. Hellwarth published a landmark paper pointing out that if coherent light fields were ever created, it would be possible to use these same methods on optical transitions. The invention of the laser in 1960 was followed quickly by a demonstration of the ‘photon echo’ – the optical version of the ‘spin echo’.

1998

R. M. Hochstrasser and collaborators proposed 2D IR spectroscopy, in analogy with two-dimensional NMR, for the determination of time-evolving structures. The spins associated with the different nuclei in NMR are replaced in the IR experiments by a network of vibrational modes whose coupling can be used to determine molecular structure and dynamics. Structures of dipeptides, tripeptides and pentapeptides were determined by 2D IR spectroscopy. The most exciting aspect of 2D IR spectroscopy, however, is the combination of its sensitivity to structure with time resolution.

Type
Chapter
Information
Methods in Molecular Biophysics
Structure, Dynamics, Function
 , pp. 562 - 572
Publisher: Cambridge University Press
Print publication year: 2007

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References

Zanni, M. T., and Hochstrasser, R. M. (2001). Two-dimensional infrared spectroscopy: a promising new method for the time resolution of structure. Curr. Opin. Str. Biol., 11, 516–522.CrossRefGoogle Scholar
Multidimensional spectroscopies. Chem. Phys. (2001), 266, 137–351. The complete issue of this journal was devoted to advances being made in optical and IR multidimensional spectroscopy.
Mukalmel, S. (1995). Principles of Nonlinear Spectroscopy. New York: Oxford University Press.Google Scholar
Asplund, M. C., Zanni, M. T., and Hochstrasser, R. M. (2000). Two-dimensional infrared spectroscopy of peptides by phase controlled femtosecond vibrational photon echoes. Proc. Natl Acad, Sci. USA, 97, 8219–8224.CrossRefGoogle ScholarPubMed
Hamm, P., Lim, M., DeGrado, W. F., and Hochstrasser, R. M. (1999). The two-dimensional IR nonlinear spectroscopy of a cyclic penta-peptide in relation of its three-dimensional structure. Proc. Natl. Acad. Sci. USA, 96, 2036–2041.CrossRefGoogle ScholarPubMed
Zanni, M. T., Gnakaran, S., Stenger, J., and Hochstrasser, R. M. (2001). Two dimensional infrared spectroscopy of solvent dependent conformations of acetyleproline-NH2. J. Phys. Chem., 105, 6520–6535.CrossRefGoogle Scholar
Rubtsov, I. V., Wang, J., and Hochstrasser, R. M. (2003). Dual-frequency 2D-IR specctroscopy heterodyned photon echo of the peptide bond. Proc. Natl. Acad. Sci. USA, 100, 5601–5606.CrossRefGoogle ScholarPubMed
Keusters, D., Tan, H. S., and Warren, W. S. (1999). Role of pulse phase and direction in two dimensional optical spectroscopy. J. Phys. Chem. A, 103, 10369–10380.CrossRefGoogle Scholar
Zanni, M. T., and Hochstrasser, R. M. (2001). Two-dimensional infrared spectroscopy: a promising new method for the time resolution of structure. Curr. Opin. Str. Biol., 11, 516–522.CrossRefGoogle Scholar
Multidimensional spectroscopies. Chem. Phys. (2001), 266, 137–351. The complete issue of this journal was devoted to advances being made in optical and IR multidimensional spectroscopy.
Mukalmel, S. (1995). Principles of Nonlinear Spectroscopy. New York: Oxford University Press.Google Scholar
Asplund, M. C., Zanni, M. T., and Hochstrasser, R. M. (2000). Two-dimensional infrared spectroscopy of peptides by phase controlled femtosecond vibrational photon echoes. Proc. Natl Acad, Sci. USA, 97, 8219–8224.CrossRefGoogle ScholarPubMed
Hamm, P., Lim, M., DeGrado, W. F., and Hochstrasser, R. M. (1999). The two-dimensional IR nonlinear spectroscopy of a cyclic penta-peptide in relation of its three-dimensional structure. Proc. Natl. Acad. Sci. USA, 96, 2036–2041.CrossRefGoogle ScholarPubMed
Zanni, M. T., Gnakaran, S., Stenger, J., and Hochstrasser, R. M. (2001). Two dimensional infrared spectroscopy of solvent dependent conformations of acetyleproline-NH2. J. Phys. Chem., 105, 6520–6535.CrossRefGoogle Scholar
Rubtsov, I. V., Wang, J., and Hochstrasser, R. M. (2003). Dual-frequency 2D-IR specctroscopy heterodyned photon echo of the peptide bond. Proc. Natl. Acad. Sci. USA, 100, 5601–5606.CrossRefGoogle ScholarPubMed
Keusters, D., Tan, H. S., and Warren, W. S. (1999). Role of pulse phase and direction in two dimensional optical spectroscopy. J. Phys. Chem. A, 103, 10369–10380.CrossRefGoogle Scholar

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