Skip to main content Accessibility help
×
Hostname: page-component-7479d7b7d-jwnkl Total loading time: 0 Render date: 2024-07-08T05:53:44.898Z Has data issue: false hasContentIssue false

4 - The Nature of Plagues 2013–14: A Year of Living Dangerously

Published online by Cambridge University Press:  24 March 2017

Angela McLean
Affiliation:
All Souls College in Oxford
Jonathan L. Heeney
Affiliation:
University of Cambridge
Sven Friedemann
Affiliation:
University of Bristol
HTML view is not available for this content. However, as you have access to this content, a full PDF is available via the 'Save PDF' action button.

Summary

The 12 months from June 2013 to May 2014 were, in many ways, typical in the emerging infectious disease events that occurred. There were no huge shocks, no massive outbreaks nor new pandemics, but every month there were important events and together the year's events form a good illustration of what is a ‘normal’ rhythm of events for emerging infectious diseases. However, after May 2014 the Ebola epidemic in West Africa (described, in its infancy, under ‘March’ in this chapter) rapidly expanded to become a very large epidemic, illustrating how quickly small outbreaks can become very large problems given circumstances that favour human to human transmission and rapid spread.

Whilst many people think of ‘emerging infections’ as only the brand new infections like SARS and HIV, the definition of emerging infections is broader and includes five types of infections that are in some sense ‘new’. Table 4.1 describes those five types and gives examples of each from the past.

In England, Public Health England (an agency of the Department of Health) routinely gathers up evidence about new infectious disease both nationally and internationally. This ‘horizon scanning’ activity is an important part of identifying new infectious hazards that may pose a risk to public health. Each month Public Health England, along with other government bodies, publishes a two-page summary of notable events of public health significance. These summaries are widely circulated in government and academia and are publically available. They form both an excellent warning of current events and a record of how events unfold over months and years.

In this article I have picked one event from each of the past twelve months to illustrate the ‘normal’ rhythm of incidents. Those events have been chosen to illustrate the five types of emerging infectious disease events. They include the three events of 2013–14 that are most likely to trigger substantial, global problems in the future: the ongoing MERS-coronavirus outbreak in the Middle East (July 2013), the ongoing zoonotic cases of Avian Influenza in China (February 2014) and the re-emergence of Polio in early 2014 (May 2014). Despite the ongoing fears about a devastating influenza pandemic, the biggest realised threat from emerging infections continues to be the evolution of antimicrobial resistance. This is a slow, chronic problem that is happening everywhere all the time and therefore never triggers a single ‘event’.

Type
Chapter
Information
Plagues , pp. 92 - 113
Publisher: Cambridge University Press
Print publication year: 2017

References

1. Public Health England (2014) Emerging Infections Monthly Summaries. www.hpa.org.uk/webw/HPAweb&Page&HPAwebAutoListName/Page/1234254470752 (accessed June 2014).
2. WHO (2014a) Antimicrobial Resistance. Global Report on Surveillance. www.who.int/drugresistance/documents/surveillancereport/en/,http://apps.who.int/iris/bitstream/10665/112642/1/9789241564748_eng.pdf?ua=1 (accessed 18 November 2016).
3. Tan, H. Le Van, Doorn, H.D.T.N., Chau, L.T. Tran Thi Hong, Phuong Tu, M.D. V., Canuti, M.D. Marta, Maarten, F.J., Menno, D. (2013) Identification of a new cyclovirus in cerebrospinal fluid of patients with acute central nervous system infections. mBio 4(3):e00231-13.Google Scholar
4. ECDC (2013a) Rapid Risk Assessment. Novel Cyclovirius CyC-VN. www.ecdc.europa.eu/en/publications/Publications/rapid-risk-assessment-Cyclovirus-final.pdf (accessed 18 November 2016).
5. Jong, M.D. de, Kinh, N. Van, Trung, N.V., Taylor, W., Wertheim, H.F., Ende, A. van der, Doorn, H.R. van (2014) Limited geographic distribution of the novel cyclovirus CyCV-VN. Scientific reports, 4 3967.
6. Chen, K., Pachter, L. (2005) Bioinformatics for whole-genome shotgun sequencing of microbial communities. PLoS Comput Bio. 1(2):e24. doi:10.1371/journal.pcbi.0010024.Google Scholar
7. WHO (2013) WHO Statement on the Second Meeting of the IHR Emergency Committee concerning MERS-CoV. www.who.int/mediacentre/news/statements/2013/mers_cov_20130717/en/ (accessed 10 June 2014).
8. ECDC (2014a) Rapid Risk Assessment Zika virus outbreak, French Polynesia. http://ecdc.europa.eu/en/publications/Publications/Zika-virus-French-Polynesia-rapid-risk-assessment.pdf (accessed 18 November 2016).
9. WHO (2014b) WHO statement on the Fifth Meeting of the IHR Emergency Committee concerning MERS-CoV. www.who.int/mediacentre/news/statements/2014/mers-20140514/en/ (accessed 10 June 2014).
10. Arinaminpathy, N., McLean, A.R. (2009) Evolution and emergence of novel human infections. Proc. R. Soc. B. 273:3075–83.Google Scholar
11. Kubiak, R.J., Arinaminpathy, N., McLean, A.R. (2010) Insights into the evolution and emergence of a novel infectious disease. PLoS Comput Biol. 6(9):e1000947 Google Scholar
12. Santos, L., Mesquita, J.R., Pereira, N. Rocha, Lima-Alves, C., Serrão, R., Figueiredo, P., Reis, J., Simões, J., Nascimento, M.S., Sarmento, A. (2013) Acute hepatitis E complicated by Guillain-Barré syndrome in Portugal, December 2012 – a case report. Euro Surveill. 18(34):pii=20563.Google Scholar
13. Kamar, N., Bendall, R.P., Peron, J.M., Cintas, P., Prudhomme, L., Mansuy, J.M. et al. (2011) Hepatitis E virus and neurologic disorders. Emerg Infect Dis. 17(2):173–9. http://dx.doi.org/10.3201/eid1702.100856. PMid:21291585. PMCid:PMC3298379.Google Scholar
14. Scharn, N., Ganzenmueller, T., Wenzel, J.J., Dengler, R., Heim, A., Wegner, F. (2013) Guillain-Barré syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c. Infection 42(1): 171–3.Google Scholar
15. WHO Global Health Observatory Data Repository. http://apps.who.int/gho/data/node.main.175 (accessed 18 November 2016).
16. Bartlett, S., (2014) Infectious disease surveillance update. Lancet Infect Dis. 14:19, ISSN 1473–3099, http://dx.doi.org/10.1016/S1473-3099(13)70372-4.Google Scholar
17. Moore, S.M., Shannon, K.L., Zelaya, C.E., Azman, A.S., Lessler, J. (2014) Epidemic risk from cholera introductions into Mexico. PLOS Curr Outbreaks. Edition 1. doi: 10.1371/currents.outbreaks.c04478c7fbd9854ef6ba923cc81eb799.
18. Kvac, M. et al. (2013) Gastroenteritis caused by the Cryptosporidium hedgehog genotype in an immunocompetent man. doi: 10.1128/JCM.02456–13 JCM.02456–13.
19. Duffy, M.R., Chen, T.H., Hancock, W.T., Powers, A.M., Kool, J.L., Lanciotti, R.S, et al. (2009) Zika virus outbreak on Yap Island, Federated States of Micronesia. N Engl J Med 360(24):2536–43.Google Scholar
20. Direction de la Santé BdVs, Polynesie Francaise.(2014) Surveillance de la dengue et du zika en Polynésie Française. www.hygiene-publique.gov.pf/spip.php?article120 (accessed 18 November 2016).
21. Pialoux, G., Gauzere, B.A., Jaureguiberry, S., Strobel, M. (2007) Chikungunya: an epidemic arbovirosis. Lancet Infect Dis. 7(5):319–27.Google Scholar
22. Vazeille, M., Moutailler, S., Coudrier, D., Rousseaux, C., Khun, H., Huerre, M. et al. (2007) Two Chikungunya isolates from the outbreak of La Reunion (Indian Ocean) exhibit different patterns of infection in the mosquito, Aedes albopictus. PLoS One. 2(11):e1168.Google Scholar
23. Rezza, G., Nicoletti, L., Angelini, R., Romi, R., Finarelli, A.C., Panning, M. et al. (2007) Infection with chikungunya virus in Italy: An outbreak in a temperate region. Lancet 370(9602):1840–6.Google Scholar
24. Grandadam, M., Caro, V., Plumet, S., Thiberge, J.M., Souares, Y., Failloux, A.B. et al. (2011) Chikungunya virus, southeastern France. Emerg Infect Dis. 17(5):910–13.Google Scholar
25. ECDC (2013b) Rapid Risk Assessment Chikungunya fever, Saint Martin. www.ecdc.europa.eu/en/publications/Publications/chikungunya-st-martin-rapid-risk-assessment.pdf (accessed 18 November 2016).
26. PAHO (2014) Number of Reported Cases of Chikungunya Fever in the Americas. www.paho.org/hq/index.php?option=com_content&view=article&id=9053&Itemid=39843 (accessed 18 November 2016).
27. Albariño, C.G., Foltzer, M., Towner, J.S., Rowe, L.A., Campbell, S., Jaramillo, C.M. et al. (2014) Novel paramyxovirus associated with severe acute febrile disease, South Sudan and Uganda, 2012. Emerg Infect Dis. DOI: 10.3201/eid2002.131620.
28. ECDC (2014b) Rapid Risk Assessment Human infection with avian influenza viruses in China. www.ecdc.europa.eu/en/publications/Publications/avian-flu-china-rapid-risk-assessment-26022014.pdf (accessed 18 November 2016).
29. Nicoll, A., Danielsson, N. (2013) A novel reassortant avian influenza A(H7N9) virus in China – what are the implications for Europe. Euro Surveill. 18(15):20452.Google Scholar
30. WHO (2014c) Ebola Virus Disease in Guinea. www.who.int/csr/don/2014_03_23_ebola/en/. (WHO 2014d) Ebola Virus Disease. www.who.int/mediacentre/factsheets/fs103/en/(accessed 18 November 2016).
31. WHO (2015) Ebola Situation Reports. http://apps.who.int/ebola/ebola-situation-reports (accessed 18 November 2016).
32. Global Polio Eradication Initiative (2014) Polio this week. www.polioeradication.org/Dataandmonitoring/Poliothisweek.aspx (accessed 18 November 2016).
33. Lozano, R. et al. (2013) Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2095–2128, ISSN 0140–6736, http://dx.doi.org/10.1016/S0140-6736(12)61728-0.Google Scholar
34. Jones, KE, Patel, NG, Levy, MA, Storeygard, A, Balk, D, Gittleman, JL, Daszak, P. (2008) Global trends in emerging infectious diseases. Nature 21;451(7181):990–3.Google Scholar
35. http://sedac.ciesin.columbia.edu/data/collection/gpw-v3/maps/gallery/browse (accessed 18 November 2016).
36. DoH (2013) Annual Report of the Chief Medical Officer Volume 2. www.gov.uk/government/publications/chief-medical-officer-annual-report-volume-2 (accessed 18 November 2016).
Assiri, A1, Al-Tawfiq, JA, Al-Rabeeah, AA, Al-Rabiah, FA, Al-Hajjar, S, Al-Barrak, A, Flemban, H, Al-Nassir, WN, Balkhy, HH, Al-Hakeem, RF, Makhdoom, HQ, Zumla, AI, Memish, ZA. (2013). Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis ;13(9):752–61.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×