This chapter considers one of the major alternatives to reductionist, mechanistic philosophy in the seventeenth century, focusing upon three key English figures: Herbert of Cherbury, Robert Greville, and Anne Conway. While these thinkers have typically been relegated to the margins of the history of philosophy and science, they nonetheless represent a significant, if largely eclipsed tradition, and one that shows how, during this period, ‘disenchanted’ understandings of nature were not the sole option, and how they could co-exist with scientific conceptions of nature. Accordingly, these figures exemplify ways of being modern and scientific without abandoning an ‘enchanted’ view of the natural world.