The International Committee Monitoring Assisted Reproductive Technologies (ICMART) has reported global ART results, helped create and improve national and regional registries, and promoted standardization of international terminology through development and revision of glossaries. These accomplishments have required the dedication and expertise of many professionals over several decades. ICMART’s history is instructive for those developing or improving their own registries. Creation of a formal structure is essential to success and sustainability of a registry. Development of relationships and formal partnerships hastens progress and benefits all stakeholders. The initial development of the glossary involved the World Health Organization (WHO). The third revision has the participation of essentially all major global stakeholders. Registries have significant value for professionals, patients and policy makers. ICMART’s registry reports utilization, profile of procedures and patients, effectiveness and safety. Despite much progress, many data collection and reporting difficulties remain. However, collaboration in addressing these challenges is resulting in major progress and also bringing many collateral benefits, especially enhanced professional relationships and harmonized approaches to problems. The future will see more comprehensive and higher quality registries, harmonized data collection, the use of “big data” analytics and artificial intelligence to increase the value of registries for patient care, research, public education and policy makers.