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Chapter 12 - Immunodeficiency-Associated Lymphoproliferative Disorders

from Section III - Mature Lymphoid Neoplasm

Published online by Cambridge University Press:  25 November 2023

By
Michele E. Paessler ,
Brian Lockhart  and
Soma Jyonouchi
Edited by
Silvia Tse Bunting ,
Xiayuan Liang ,
Michele E. Paessler  and
Satheesh Chonat
Silvia Tse Bunting
Affiliation:
Cleveland Clinic Florida Weston
Xiayuan Liang
Affiliation:
University of Colorado
Michele E. Paessler
Affiliation:
University of Pennsylvania School of Medicine
Satheesh Chonat
Affiliation:
Emory University, Atlanta
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Summary

Immunodeficiency-associated lymphoproliferative disorders (IA-LPDs) encompass a heterogeneous group of disorders that stem from diverse clinical settings and underlying disorders. These disorders may be benign lymphoproliferations to aggressive lymphomas. The World Health Organization (WHO) broadly classifies IA-LPDs into four groups: posttransplant lymphoproliferative disorders (PTLDs), lymphomas associated with HIV, lymphoproliferations associated with primary immune disorders, and other iatrogenic lymphoproliferative disorders. This chapter focuses on IA-LPDs of primary immune deficiencies seen commonly in the pediatric population, HIV-associated lymphoma, and iatrogenic lymphoproliferations.

Type
Chapter
Information
Atlas of Pediatric Hematopathology , pp. 106 - 126
Publisher: Cambridge University Press
Print publication year: 2023

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