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Chapter 16 - Ventilation–Perfusion Zones in the Lung

from Section 2 - Respiratory Physiology

Published online by Cambridge University Press:  31 July 2019

David Chambers ,
Christopher Huang  and
Gareth Matthews
David Chambers
Affiliation:
Salford Royal NHS Foundation Trust
Christopher Huang
Affiliation:
University of Cambridge
Gareth Matthews
Affiliation:
University of Cambridge
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Summary

In the upright position, ventilation and perfusion both increase from the top to the bottom of the lung. This was previously attributed to the effect of gravity (the so-called gravitational model), but it is now thought that structural similarities between the pulmonary arteries and bronchioles contribute (see Chapter 15).

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Chapter
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Basic Physiology for Anaesthetists , pp. 71 - 73
Publisher: Cambridge University Press
Print publication year: 2019

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References

Further reading

West, J. B.. Ventilation/Blood Flow and Gas Exchange, 6th edition. Hoboken, Wiley-Blackwell, 1990.Google Scholar
Galvin, I., Drummond, G. B., Nirmalan, M.. Distribution of blood flow and ventilation in the lung: gravity is not the only factor. Br J Anaesth 2007; 98(4): 420–8.CrossRefGoogle Scholar

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