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Chapter 14 - Ingestions

Published online by Cambridge University Press:  01 June 2018

By
Stephen M. Blumberg ,
Vincent Nguyen  and
Katherine J. Chou
Edited by
Jeffrey C. Gershel  and
Ellen F. Crain
Jeffrey C. Gershel
Affiliation:
Albert Einstein College of Medicine, New York
Ellen F. Crain
Affiliation:
Albert Einstein College of Medicine, New York
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Clinical Manual of Emergency Pediatrics , pp. 442 - 492
Publisher: Cambridge University Press
Print publication year: 2018

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References

Bibliography

Albertson, TE, Owen, KP, Sutter, ME, Chan, AL. Gastrointestinal decontamination in the acutely poisoned patient. Int J Emerg Med. 2011;12(4):65.CrossRefGoogle Scholar
Barrueto, F Jr., Gattu, R, Mazer-Amirshahi, M. Updates in the general approach to the pediatric poisoned patient. Pediatr Clin North Am. 2013;60(5):1203–1220.Google Scholar
Calello, DP, Henretig, FM. Pediatric toxicology: specialized approach to the poisoned child. Emerg Med Clin North Am. 2014;32(1):29–52.Google Scholar
Marraffa, JM, Cohen, V, Howland, MA. Antidotes for toxicological emergencies: a practical review. Am J Health Syst Pharm. 2012;69(3):199–212.CrossRefGoogle ScholarPubMed
Mowry, JB, Spyker, DA, Cantilena, LR Jr, McMillan, N, Ford, M. 2013 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 31st annual report. Clin Toxicol (Phila). 2014;52(10):1032–1283.CrossRefGoogle Scholar

Bibliography

Blackford, MG, Felter, T, Gothard, MD, Reed, MD. Assessment of the clinical use of intravenous and oral N-acetylcysteine in the treatment of acute acetaminophen poisoning in children: a retrospective review. Clin Ther. 2011;33(9):1322–1330.Google Scholar
Lancaster, EM, Hiatt, JR, Zarrinpar, A. Acetaminophen hepatotoxicity: an updated review. Arch Toxicol. 2015;89(2):193–199.Google Scholar
Rumack, BH, Bateman, DN. Acetaminophen and acetylcysteine dose and duration: past, present and future. Clin Toxicol. 2012;50(2):91–98.CrossRefGoogle ScholarPubMed
Seifert, SA, Kirschner, RI, Martin, TG, et al. Acetaminophen concentrations prior to 4 hours of ingestion: impact on diagnostic decision-making and treatment. Clin Toxicol (Phila). 2015;53(7):618–623.CrossRefGoogle ScholarPubMed
Shastri, N. Intravenous acetaminophen use in pediatrics. Pediatr Emerg Care. 2015;31(6):444–448.CrossRefGoogle ScholarPubMed

Bibliography

Cooper, WO, Habel, LA, Sox, CM, et al. ADHD drugs and serious cardiovascular events in children and young adults. N Engl J Med. 2011;365:1896–1904.Google Scholar
Cortese, S, Holtmann, M, Banaschewski, T, et al. Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents. J Child Psychol Psychiatry. 2013;54(3):227–246.Google Scholar
Spiller, HA, Hays, HL, Aleguas, A. Overdose of drugs for attention-deficit hyperactivity disorder: clinical presentation, mechanisms of toxicity, and management. CNS Drugs. 2013;27:531–543.CrossRefGoogle ScholarPubMed

Bibliography

Dawson, AH, Buckley, NA. Pharmacological management of anticholinergic delirium: theory, evidence and practice. Br J Clin Pharmacol. 2016;81(3):516–524.Google Scholar
Glatstein, MM, Alabdulrazzaq, F, Garcia-Bournissen, F, Scolnik, D. Use of physostigmine for hallucinogenic plant poisoning in a teenager: case report and review of the literature. Am J Ther. 2012;19(5):384–388.Google Scholar
Glatstein, M, Alabdulrazzaq, F, Scolnik, D. Belladonna alkaloid intoxication: the 10-year experience of a large tertiary care pediatric hospital. Am J Ther. 2016;23(1):e74–e77.Google Scholar

Bibliography

Bruccoleri, RE, Burns, MM. A literature review of the use of sodium bicarbonate for the treatment of QRS widening. J Med Toxicol. 2016;12(1):121–129.CrossRefGoogle ScholarPubMed
Kant, S, Liebelt, E. Recognizing serotonin toxicity in the pediatric emergency department. Pediatr Emerg Care. 2012;28(8):817–821.CrossRefGoogle ScholarPubMed
Stork, CM. Serotonin reuptake inhibitors and atypical antidepressants. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill, 2015; 1018–1028.Google Scholar
Wang, RZ, Vashistha, V, Kaur, S, Houchens, NW. Serotonin syndrome: preventing, recognizing, and treating it. Cleve Clin J Med. 2016;83(11):810–817.Google Scholar

Bibliography

Meli, M, Rauber-Lüthy, C, Hoffmann-Walbeck, P, et al. Atypical antipsychotic poisoning in young children: a multicentre analysis of poisons centres data. Eur J Pediatr. 2014;173:743–750.CrossRefGoogle ScholarPubMed
Pileggi, DJ, Cook, AM. Neuroleptic malignant syndrome. Ann Pharmacother. 2016;50(11):973–981.Google Scholar
Rasimas, JJ, Liebelt, EL. Adverse effects and toxicity of the atypical antipsychotics: what is important for the pediatric emergency medicine practitioner. Clin Pediatr Emerg Med. 2012;13(4):300–310.CrossRefGoogle ScholarPubMed
Tse, L, Barr, AM, Scarapicchia, V, Vila-Rodriguez, F. Neuroleptic malignant syndrome: a review from a clinically oriented perspective. Curr Neuropharmacol. 2015;13(3):395–406.Google Scholar

Bibliography

Graudins, A, Lee, HM, Druda, D. Calcium channel antagonist and beta-blocker overdose: antidotes and adjunct therapies. Br J Clin Pharmacol. 2016;81(3):453–461.Google Scholar
Jang, DH, Spyres, MB, Fox, L, Manini, AF. Toxin-induced cardiovascular failure. Emerg Med Clin North Am. 2014;32(1):79–102.CrossRefGoogle ScholarPubMed
Palatnick, W, Jelic, T. Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity. Emerg Med Pract. 2014;16(2):1–19.Google ScholarPubMed
Truitt, CA, Brooks, DE, Dommer, P, LoVecchio, F. Outcomes of unintentional beta-blocker or calcium channel blocker overdoses: a retrospective review of poison center data. J Med Toxicol. 2012;8(2):135–139.Google Scholar

Bibliography

Beauchamp, GA, Johnson, AR, Crouch, BI, et al. A retrospective study of clinical effects of powdered caffeine exposures reported to three US poison control centers. J Med Toxicol. 2016;12(3):295–300.CrossRefGoogle ScholarPubMed
Jabbar, SB, Hanly, MG. Fatal caffeine overdose: a case report and review of literature. Am J Forensic Med Pathol. 2013;34(4):321–324.CrossRefGoogle ScholarPubMed
Seifert, SM, Schaechter, JL, Hershorin, ER, Lipshultz, SE. Health effects of energy drinks on children, adolescents, and young adults. Pediatrics. 2011;127(3):511–528.CrossRefGoogle ScholarPubMed

Bibliography

Graudins, A, Lee, HM, Druda, D. Calcium channel antagonist and beta-blocker overdose: antidotes and adjunct therapies. Br J Clin Pharmacol. 2016;81(3):453–461.Google Scholar
Palatnick, W, Jelic, T. Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity. Emerg Med Pract. 2014;16(2):1–19.Google ScholarPubMed
Shenoy, S, Lankala, S, Adigopula, S. Management of calcium channel blocker overdoses. J Hosp Med. 2014;9(10):663–668.Google Scholar
St-Onge, M, Dubé, PA, Gosselin, S, et al. Treatment for calcium channel blocker poisoning: a systematic review. Clin Toxicol (Phila). 2014; 52:926–944.Google Scholar

Bibliography

Bleecker, ML. Carbon monoxide intoxication. Handb Clin Neurol. 2015;131:191–203.Google Scholar
Cho, CH, Chiu, NC, Ho, CS, Peng, CC. Carbon monoxide poisoning in children. Pediatr Neonatol. 2008;49:121–125.Google Scholar
Macnow, TE, Waltzman, ML. Carbon monoxide poisoning in children: diagnosis and management in the emergency department. Pediatr Emerg Med Pract. 2016;13(9):1–24.Google Scholar
Tomaszewski, C: Carbon monoxide. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill Education, 2015; 1581–1593.Google Scholar
Weaver, LK. Carbon monoxide poisoning. N Engl J Med. 2009;360:1217–1225.Google Scholar

Bibliography

Arevalo-Silva, C, Eliashar, R, Wohlgelernter, J, Elidan, J, Gross, M. Ingestion of caustic substances: a 15 year experience. Laryngoscope. 2006;116:1422–1426.Google Scholar
Shub, MD. Therapy of caustic ingestion: new treatment considerations. Curr Opin Pediatr. 2015;27(5):609–613.CrossRefGoogle ScholarPubMed
Uygun, I. Caustic oesophagitis in children: prevalence, the corrosive agents involved, and management from primary care through to surgery. Curr Opin Otolaryngol Head Neck Surg. 2015;23(6):423–432.Google Scholar
Valdez, AL, Casavant, MJ, Spiller, HA, et al. Pediatric exposure to laundry detergent pods. Pediatrics. 2014;134:1127–1135.Google Scholar
Wightman, RS, Read, KB, Hoffman, RS. Evidence-based management of caustic exposures in the emergency department. Emerg Med Pract. 2016;18(5):1–17.Google ScholarPubMed

Bibliography

Eddleston, M, Chowdhury, FR. Pharmacological treatment of organophosphorus insecticide poisoning: the old and the (possible) new. Br J Clin Pharmacol. 2016;81(3):462–470.Google Scholar
Eddleston, M, Clark, RF. Insecticides: organic phosphorus compounds and carbamates. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill, 2015; 1409–1424.Google Scholar
King, AM, Aaron, CK. Organophosphate and carbamate poisoning. Emerg Med Clin North Am. 2015;33(1):133–151.Google Scholar
Vale, A, Lotti, M. Organophosphorus and carbamate insecticide poisoning. Handb Clin Neurol. 2015;131:149–168.Google Scholar

Bibliography

Ahmad, SA, Scolnik, D, Snehal, V, Glatstein, M. Use of naloxone for clonidine intoxication in the pediatric age group: case report and review of the literature. Am J Ther. 2015;22(1):e14–e16.Google Scholar
Spiller, HA, Hays, HL, Aleguas, A Jr. Overdose of drugs for attention-deficit hyperactivity disorder: clinical presentation, mechanisms of toxicity, and management. CNS Drugs. 2013;27(7):531–543.CrossRefGoogle ScholarPubMed
Wang, GS, Le Lait, MC, Heard, K. Unintentional pediatric exposures to central alpha-2 agonists reported to the National Poison Data System. J Pediatr. 2014;164(1):149–152.Google Scholar

Bibliography

Isbister, GK, Prior, F, Kilham, HA. Restricting cough and cold medicines in children. J Paediatr Child Health. 2012;48(2):91–98.Google Scholar
Paul, IM, Reynolds, KM, Kauffman, RE, et al. Adverse events associated with pediatric exposures to dextromethorphan. Clin Toxicol (Phila). 2017;55(1):25–32.Google Scholar

Bibliography

Chan, BS, Buckley, NA. Digoxin-specific antibody fragments in the treatment of digoxin toxicity. Clin Toxicol (Phila). 2014;52(8):824–836.Google Scholar
Moffett, BS, Garner, A, Zapata, T, et al. Serum digoxin concentrations and clinical signs and symptoms of digoxin toxicity in the paediatric population. Cardiol Young. 2016;26(3):493–498.CrossRefGoogle ScholarPubMed
Palatnick, W, Jelic, T. Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity. Emerg Med Pract. 2014;16(2):1–19.Google Scholar
Pincus, M. Management of digoxin toxicity. Aust Prescr. 2016;39(1):18–20.Google Scholar

Bibliography

Huestis, MA, Tyndale, RF. Designer drugs 2.0. Clin Pharmacol Ther. 2017;101(2):152–157.Google Scholar
Nelson, ME, Bryant, SM, Aks, SE. Emerging drugs of abuse. Emerg Med Clin North Am. 2014;32:1–28.CrossRefGoogle ScholarPubMed
Richards, JR, Garber, D, Laurin, EG, et al. Treatment of cocaine cardiovascular toxicity: a systematic review. Clin Toxicol (Phila). 2016;54(5):345–364.Google Scholar
Tenenbein, M. Do you really need that emergency drug screen? Clin Toxicol (Phila). 2009;47:286–291.Google Scholar

Bibliography

Minera, G, Robinson, E. Accidental acute alcohol intoxication in infants: review and case report. J Emerg Med. 2014;47(5):524–526.Google Scholar
Rayar, P, Ratnapalan, S. Pediatric ingestions of house hold products containing ethanol: a review. Clin Pediatr (Phila). 2013;52:203–209.CrossRefGoogle ScholarPubMed
Yip, L. Ethanol. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill, 2015; 1082–1093.Google Scholar

Bibliography

Hussain, SZ, Bousvaros, A, Gilger, M, et al. Management of ingested magnets in children. J Pediatr Gastroenterol Nutr. 2012;55(3):239–242.Google Scholar
Jayachandra, S, Eslick, GD. A systematic review of paediatric foreign body ingestion: presentation, complications, and management. Int J Pediatr Otorhinolaryngol. 2013;77(3):311–317.CrossRefGoogle ScholarPubMed
Kramer, RE, Lerner, DG, Lin, T, Manfredi, M, et al. Management of ingested foreign bodies in children: a clinical report of the NASPGHAN Endoscopy Committee. J Pediatr Gastroenterol Nutr. 2015;60(4):562–574.CrossRefGoogle ScholarPubMed
Litovitz, T, Whitaker, N, Clark, L, White, NC, Marsolek, M. Emerging battery ingestion hazard: clinical implications. Pediatrics. 2010;125(6):1168–1177.Google Scholar
Wright, CC, Closson, FT. Updates in pediatric gastrointestinal foreign bodies. Pediatr Clin North Am. 2013;60(5):1221–1239.CrossRefGoogle ScholarPubMed

Bibliography

Beuhler, MC, Gala, PK, Wolfe, HA, Meaney, PA, Henretig, FM. Laundry detergent “pod” ingestions: a case series and discussion of recent literature. Pediatr Emerg Care. 2013;29(6):743–747CrossRefGoogle ScholarPubMed
Makrygianni, EA, Palamidou, F, Kaditis, AG. Respiratory complications following hydrocarbon aspiration in children. Pediatr Pulmonol. 2016;51(6):560–569.Google Scholar
Niaz, K, Bahadar, H, Maqbool, F, Abdollahi, M. A review of environmental and occupational exposure to xylene and its health concerns. EXCLI J. 2015;14:1167–1186.Google Scholar
Tormoehlen, LM, Tekulve, KJ, Nañagas, KA. Hydrocarbon toxicity: a review. Clin Toxicol (Phila). 2014;52(5):479–489.Google Scholar

Bibliography

Chang, TP, Rangan, C. Iron poisoning: a literature-based review of epidemiology, diagnosis, and management. Pediatr Emerg Care. 2011;27(10):978–985.CrossRefGoogle ScholarPubMed
Gumber, MR, Kute, VB, Shah, PR, et al. Successful treatment of severe iron intoxication with gastrointestinal decontamination, deferoxamine, and hemodialysis. Ren Fail. 2013;35(5):729–731.Google Scholar
Madiwale, T, Liebelt, E. Iron: not a benign therapeutic drug. Curr Opin Pediatr. 2006;18:174–179.Google Scholar
Thanacoody, R, Caravati, EM, Troutman, B, et al. Position paper update: whole bowel irrigation for gastrointestinal decontamination of overdose patients. Clin Toxicol (Phila). 2015;53:5–12.Google Scholar

Bibliography

Chauhan, V, Sharma, R, Sharma, K, et al. Naphthalene poisoning manifesting as hemoglobinuria. Toxicol Int. 2014;21(3):314–315.Google Scholar
Kovacic, P, Somanathan, R. Nitroaromatic compounds: environmental toxicity, carcinogenicity, mutagenicity, therapy and mechanism. J Appl Toxicol. 2014;34(8):810–824.Google Scholar
MacKinney, TG, Soti, KR, Shrestha, P, Basnyat, B. Camphor: an herbal medicine causing grand mal seizures. BMJ Case Rep. 2015 11;2015.Google Scholar
Sudakin, DL, Stone, DL, Power, L. Naphthalene mothballs: emerging and recurring issues and their relevance to environmental health. Curr Top Toxicol. 2011;7:13–19.Google Scholar

Bibliography

Argentieri, J, Morrone, K, Pollack, Y. Acetaminophen and ibuprofen overdosage. Pediatr Rev. 2012;33(4):188–189.Google Scholar
Hunter, LJ, Wood, DM, Dargan, PI. The patterns of toxicity and management of acute nonsteroidal anti-inflammatory drug (NSAID) overdose. Open Access Emerg Med. 2011;3:39–48.Google Scholar
Lodise, M, De-Giorgio, F, Rossi, R, d’Aloja, E, Fucci, N. Acute ibuprofen intoxication: report on a case and review of the literature. Am J Forensic Med Pathol. 2012;33(3):242–246.Google Scholar
Unzueta, A, Vargas, HE. Nonsteroidal anti-inflammatory drug-induced hepatoxicity. Clin Liver Dis. 2013;17(4):643–656Google Scholar

Bibliography

Dougherty, PP, Lee, SC, Lung, D, Klein-Schwartz, W. Evaluation of the use and safety of octreotide as antidotal therapy for sulfonylurea overdose in children. Pediatr Emerg Care. 2013;29(3):292–295.Google Scholar
Glatstein, M, Scolnik, D, Bentur, Y. Octreotide for the treatment of sulfonylurea poisoning. Clin Toxicol (Phila). 2012;50:795–804.Google Scholar
Klein-Schwartz, W, Stassinos, GL, Isbister, GK. Treatment of sulfonylurea and insulin overdose. Br J Clin Pharmacol. 2016;81(3):496–504.CrossRefGoogle ScholarPubMed
Lung, DD, Olson, KR. Hypoglycemia in pediatric sulfonylurea poisoning: an 8-year poison center retrospective study. Pediatrics. 2011;127:e1558–e1564.Google Scholar

Bibliography

Card, DJ, Francis, S, Deuchande, K, Harrington, DJ. Superwarfarin poisoning and its management. BMJ Case Rep. 2014;2014. DOI: 10.1136/bcr-2014-206360.Google Scholar
Fang, Y, Ye, D, Tu, C, et al. Superwarfarin rodent poisons and hemorrhagic disease. Epidemiology. 2012;23(6):932–934.Google Scholar
King, N, Tran, MH. Long-acting anticoagulant rodenticide (superwarfarin) poisoning: a review of its historical development, epidemiology, and clinical management. Transfus Med Rev. 2015;29(4):250–258Google Scholar
Schulman, S, Furie, B. How I treat poisoning with vitamin K antagonists. Blood. 2015;125(3):438–442.Google Scholar

Bibliography

Calello, DP, Henretig, FM. Pediatric toxicology: specialized approach to the poisoned child. Emerg Med Clin North Am. 2014;32(1):29–52.Google Scholar
Flomenbaum, NE. Salicylates. In Hoffman, RS, Howland, MA, Lewin, NA, Nelson, LS, Goldfrank, LR (eds.) Goldfrank’s Toxicologic Emergencies (10th edn.). New York: McGraw-Hill, 2015; 516–527.Google Scholar
Juurlink, DN, Gosselin, S, Kielstein, JT, et al. Extracorporeal treatment for salicylate poisoning: systematic review and recommendations from the EXTRIP workgroup. Ann Emerg Med. 2015;66(2):165–181.Google Scholar
Robinson, K, Rauch, A, Hannan, L. Salicylate poisoning following topical administration of methylsalicylate. Emerg Med Australas. 2015;27(4):374–375.Google Scholar
Shively, RM, Hoffman, RS, Manini, AF. Acute salicylate poisoning: risk factors for severe outcome. Clin Toxicol (Phila). 2017;55(3):175–180.CrossRefGoogle ScholarPubMed

Bibliography

Jammalamadaka, D, Raissi, S. Ethylene glycol, methanol, and isopropyl alcohol intoxication. Am J Med Sci. 2010;339:276–281.Google Scholar
Kraut, JA. Diagnosis of toxic alcohols: limitations of present methods. Clin Toxicol (Phila). 2015;53(7):589–595.Google Scholar
Kruse, JA. Methanol and ethylene glycol intoxication. Crit Care Clin. 2012;28(4):661–711.Google Scholar
McMartin, K, Jacobsen, D, Hovda, KE. Antidotes for poisoning by alcohols that form toxic metabolites. Br J Clin Pharmacol. 2016;81(3):505–515.Google Scholar

Bibliography

Body, R, Bartram, T, Azam, F, Mackway-Jones, K. Guidelines in Emergency Medicine Network (GEMNet): guideline for the management of tricyclic antidepressant overdose. Emerg Med J. 2011;28(4):347–368.Google Scholar
Bruccoleri, RE, Burns, MM. A literature review of the use of sodium bicarbonate for the treatment of QRS widening. J Med Toxicol. 2016;12(1):121–129.Google Scholar
Carvalho, AF, Sharma, MS, Brunoni, AR, Vieta, E, Fava, GA. The safety, tolerability and risks associated with the use of newer generation antidepressant drugs: a critical review of the literature. Psychother Psychosom. 2016;85(5):270–288.Google Scholar
O’Sullivan, JC, Johnson, AD, Waterman, MA. Comparative resuscitation measures for the treatment of desipramine overdose. Mil Med. 2014;179(11):1266–1272.CrossRefGoogle ScholarPubMed

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