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Chapter 6 - Artifacts and pitfalls in diffusion MR imaging

from Section 1 - Physiological MR techniques

Published online by Cambridge University Press:  05 March 2013

By
Martin A. Koch  and
David G. Norris
Edited by
Jonathan H. Gillard ,
Adam D. Waldman  and
Peter B. Barker
Jonathan H. Gillard
Affiliation:
University of Cambridge
Adam D. Waldman
Affiliation:
Imperial College London
Peter B. Barker
Affiliation:
The Johns Hopkins University School of Medicine
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Summary

Introduction

Although some diffusion-weighted imaging (DWI) techniques have entered the stage of clinical routine application, particularly in the detection of cerebral infarction, obtaining and interpreting diffusion imaging results is not always straightforward. This reflects both the numerous technical difficulties and also the sensitivity of diffusion imaging experiments to phenomena other than diffusion.[1,2] Further complications arise from the sheer number of diffusion parameters that can be derived from the measurement in biological tissue, such as eigenvectors, eigenvalues, anisotropy, and trace of the diffusion tensor, diffusion coefficients for a given direction, and so on. This chapter aims at providing an overview of the most important difficulties encountered in MR diffusion imaging.

The parameters derived from DWI can be affected by a number of sources of error. These error sources may be divided into two groups, according to whether they arise from properties of the measurement apparatus or from properties of the measured object itself.

Type
Chapter
Information
Clinical MR Neuroimaging
Physiological and Functional Techniques
 , pp. 79 - 85
Publisher: Cambridge University Press
Print publication year: 2009

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