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Chapter 5a - Vaginal Aplasia: Creatsas Vaginoplasty

from Section 1 - Basic Sciences in Gynaecology

Published online by Cambridge University Press:  24 November 2021

Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona-Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is a rare congenital abnormality of the female genital tract presenting with aplasia of the uterus and the upper two-thirds of the vagina in an otherwise normal 46XX individual. The incidence is approximately one case in 4000 women. The syndrome is frequently associated with other non-gynaecological defects, such as urinary tract anomalies, vertebral deformities and, to a lesser extent, auditory and cardiac lesions. The absence of the vagina and the uterus have a profound psychological impact on the young woman’s sense of femininity, so the demand for a sexual life makes the creation of a neovagina strongly advisable. Diagnosis is based on the history, the clinical and gynaecological examination, ultrasonography, including the urinary tract examination to exclude relative anomalies, and laparoscopy and hysteroscopy to diagnose and classify the relative uterovaginal anomaly.

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Publisher: Cambridge University Press
Print publication year: 2021

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References

Botsis, D, Deligeoroglou, E, Christopoulos, P, et al. Ultrasound imaging to evaluate Creatsas vaginoplasty. Int J Gynaecol Obstet 2005;89:3134.Google Scholar
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Creatsas, G, Deligeorolgou, E, Christopoulos, P. Creation of a neovagina after Creatsas modification of Williams vaginoplasty for the treatment of 200 patients with Mayer–Rokitansky–Kuster–Hauser syndrome. Fertil Steril 2010;94:18481852.CrossRefGoogle ScholarPubMed
Deligeoroglou, E, Christopoulos, P, Creatsas, G. A unique case of descending salpingitis and functioning endometrium in a Mullerian remnant in a woman with Mayer–Rokitansky–Kuster–Hauser syndrome. Fertil Steril 2005;83:15471548.CrossRefGoogle Scholar
Deligeoroglou, A, Kontoravdis, E, Makrakis, P, et al. Development of leiomyomas on the uterine remnant of two women with Mayer–Rokitansky–Kuster–Hauser syndrome. Fertil Steril 2004;81:13851387.CrossRefGoogle ScholarPubMed

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