Book contents
- Frontmatter
- Contents
- Editor, Associate Editors, Artistic Consultant, and Contributors
- Preface
- PART I CONTEXT
- 1 The Endothelium in History
- 2 Introductory Essay: Evolution, Comparative Biology, and Development
- 3 Evolution of Cardiovascular Systems and Their Endothelial Linings
- 4 The Evolution and Comparative Biology of Vascular Development and the Endothelium
- 5 Fish Endothelium
- 6 Hagfish: A Model for Early Endothelium
- 7 The Unusual Cardiovascular System of the Hemoglobinless Antarctic Icefish
- 8 The Fish Endocardium: A Review on the Teleost Heart
- 9 Skin Breathing in Amphibians
- 10 Avian Endothelium
- 11 Spontaneous Cardiovascular and Endothelial Disorders in Dogs and Cats
- 12 Giraffe Cardiovascular Adaptations to Gravity
- 13 Energy Turnover and Oxygen Transport in the Smallest Mammal: The Etruscan Shrew
- 14 Molecular Phylogeny
- 15 Darwinian Medicine: What Evolutionary Medicine Offers to Endothelium Researchers
- 16 The Ancestral Biomedical Environment
- 17 Putting Up Resistance: Maternal–Fetal Conflict over the Control of Uteroplacental Blood Flow
- 18 Xenopus as a Model to Study Endothelial Development and Modulation
- 19 Vascular Development in Zebrafish
- 20 Endothelial Cell Differentiation and Vascular Development in Mammals
- 21 Fate Mapping
- 22 Pancreas and Liver: Mutual Signaling during Vascularized Tissue Formation
- 23 Pulmonary Vascular Development
- 24 Shall I Compare the Endothelium to a Summer's Day: The Role of Metaphor in Communicating Science
- 25 The Membrane Metaphor: Urban Design and the Endothelium
- 26 Computer Metaphors for the Endothelium
- PART II ENDOTHELIAL CELL AS INPUT-OUTPUT DEVICE
- PART III VASCULAR BED/ORGAN STRUCTURE AND FUNCTION IN HEALTH AND DISEASE
- PART IV DIAGNOSIS AND TREATMENT
- PART V CHALLENGES AND OPPORTUNITIES
- Index
- Plate section
25 - The Membrane Metaphor: Urban Design and the Endothelium
from PART I - CONTEXT
Published online by Cambridge University Press: 04 May 2010
- Frontmatter
- Contents
- Editor, Associate Editors, Artistic Consultant, and Contributors
- Preface
- PART I CONTEXT
- 1 The Endothelium in History
- 2 Introductory Essay: Evolution, Comparative Biology, and Development
- 3 Evolution of Cardiovascular Systems and Their Endothelial Linings
- 4 The Evolution and Comparative Biology of Vascular Development and the Endothelium
- 5 Fish Endothelium
- 6 Hagfish: A Model for Early Endothelium
- 7 The Unusual Cardiovascular System of the Hemoglobinless Antarctic Icefish
- 8 The Fish Endocardium: A Review on the Teleost Heart
- 9 Skin Breathing in Amphibians
- 10 Avian Endothelium
- 11 Spontaneous Cardiovascular and Endothelial Disorders in Dogs and Cats
- 12 Giraffe Cardiovascular Adaptations to Gravity
- 13 Energy Turnover and Oxygen Transport in the Smallest Mammal: The Etruscan Shrew
- 14 Molecular Phylogeny
- 15 Darwinian Medicine: What Evolutionary Medicine Offers to Endothelium Researchers
- 16 The Ancestral Biomedical Environment
- 17 Putting Up Resistance: Maternal–Fetal Conflict over the Control of Uteroplacental Blood Flow
- 18 Xenopus as a Model to Study Endothelial Development and Modulation
- 19 Vascular Development in Zebrafish
- 20 Endothelial Cell Differentiation and Vascular Development in Mammals
- 21 Fate Mapping
- 22 Pancreas and Liver: Mutual Signaling during Vascularized Tissue Formation
- 23 Pulmonary Vascular Development
- 24 Shall I Compare the Endothelium to a Summer's Day: The Role of Metaphor in Communicating Science
- 25 The Membrane Metaphor: Urban Design and the Endothelium
- 26 Computer Metaphors for the Endothelium
- PART II ENDOTHELIAL CELL AS INPUT-OUTPUT DEVICE
- PART III VASCULAR BED/ORGAN STRUCTURE AND FUNCTION IN HEALTH AND DISEASE
- PART IV DIAGNOSIS AND TREATMENT
- PART V CHALLENGES AND OPPORTUNITIES
- Index
- Plate section
Summary
Scholars, from scientists to artists, have been drawing analogies between the human body and the built environment for centuries. The functioning of major transportation networks within a city has frequently been explained in terms of how the circulatory system in a body works, and vice-versa, with major roadways compared with arteries and veins. The comparisons are surprisingly interesting. In both systems, major and minor pathways exist, with varying capacities and roles that connect and/or service different functional components of the overall city or of the body. In both systems, clogging, with its unfortunate consequences is caused by either temporary blockage or longer-term capacity reduction due to narrowing of pathways. A blockage at one point can affect far-removed locations. Mathematical models that bear some similarities have been developed to describe each of these systems. In the urban context, for example, the effects of closing a major pathway on traffic redistribution throughout the whole system of roadways can be predicted. These models find everyday use in our cities.
Although analogies between urban functions and human bodily functions are common, we should carefully think about their appropriate use. The two systems are obviously radically different for innumerable reasons, and this in turn undermines the usefulness of the analogy. It is axiomatic that nothing can ever be proven by use of analogies or metaphors to begin with. Analogies or metaphors, however, do often prompt the scholars or researchers in each field to view their own problems in a different light. New approaches to thorny issues are occasionally suggested (4).
- Type
- Chapter
- Information
- Endothelial Biomedicine , pp. 211 - 214Publisher: Cambridge University PressPrint publication year: 2007