Self-initiated expatriates (SIEs) are an important group of the globally mobile workforce. In contrast to assigned expatriates (AEs), SIEs relocate on their own volition and without company support. In recent years, the literature on SIEs has started to burgeon leading to an enhanced knowledge of SIEs. The purpose of this chapter is to first review and summarize central findings in the nascent body of research concerned with SIEs. In this regard, we focus on the following key areas of inquiry: definitions of SIEs, their (demographic) profiles, main motivations to relocate, cross-cultural adjustment, as well as career experiences, and outcomes of self-initiated expatriation. In second step, based on our overview of the extant literatures, we outline directions for future research on SIEs in each key area. The suggested future research avenues will be helpful to guide the next generation of studies on SIEs and to move this stream of research ahead.