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Chapter 33 - Cardiac Disease in Pregnancy (Content last reviewed: 11th November 2020)

from Section 5 - Late Pregnancy – Maternal Problems

Published online by Cambridge University Press:  15 November 2017

David James
Affiliation:
University of Nottingham
Philip Steer
Affiliation:
Imperial College London
Carl Weiner
Affiliation:
University of Kansas
Bernard Gonik
Affiliation:
Wayne State University, Detroit
Stephen Robson
Affiliation:
University of Newcastle
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Summary

Serious maternal cardiac disease complicating pregnancy is relatively uncommon; however, it can have a significant adverse effect on maternal and fetal outcomes despite modern cardiac care. The overall prevalence of chronic heart disease complicating pregnancy is estimated to be 1.4% in the US.

Type
Chapter
Information
High-Risk Pregnancy
Management Options
, pp. 899 - 942
Publisher: Cambridge University Press
First published in: 2017

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References

Kuklina, E, Callaghan, W. Chronic heart disease and severe obstetric morbidity among hospitalisations for pregnancy in the USA: 1995–2006. BJOG 2011; 118: 345–52.Google Scholar
Knight, M, Bunch, K, Tuffnell, D, et al., on behalf of MBRRACE-UK. Saving Lives, Improving Mothers' Care: Lessons Learned to Inform Maternity Care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2015–17. Oxford: National Perinatal Epidemiology Unit, University of Oxford, 2019. www.npeu.ox.ac.uk/mbrrace-uk/reports (accessed August 2020).Google Scholar
Creanga, AA, Syverson, C, Seed, K, Callaghan, WM. Pregnancy-related mortality in the United States, 2011–2013. Obstet Gynecol 2017; 1030: 366–73. https://doi.org/10.1097/AOG.0000000000002114.Google Scholar
Leary, PJ, Leary, SE, Stout, KK, Schwartz, SM, Easterling, TR. Maternal, perinatal, and postneonatal outcomes in women with chronic heart disease in Washington State. Obstet Gynecol 2012; 120: 1283–90.CrossRefGoogle ScholarPubMed
Sermer, M, Colman, J, Siu, S. Pregnancy complicated by heart disease: a review of Canadian experience. J Obstet Gynaecol 2003; 23: 540–4.CrossRefGoogle ScholarPubMed
Siu, SC, Sermer, M, Colman, JM, et al. Prospective multicenter study of pregnancy outcome in women with heart disease. Circulation 2001; 104: 515–21.Google Scholar
Stangl, V, Schad, J, Gossing, G, et al. Maternal heart disease and pregnancy outcome: a single-centre experience. Eur J Heart Fail 2008; 10: 855–60.Google Scholar
Siu, SC, Sermer, M, Harrison, DA, et al. Risk and predictors for pregnancy-related complications in women with heart disease. Circulation 1997; 96: 2789–94.Google Scholar
Ruys, TP, Roos-Hesselink, JW, Hall, R, et al. Heart failure in pregnant women with cardiac disease: data from the ROPAC. Heart 2014; 100: 231–8.CrossRefGoogle ScholarPubMed
Regitz-Zagrosek, V, Lundqvist, CB, Borghi, C, et al. ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC). Eur Heart J 2011; 32: 3147–97. doi: 10.1093/eurheartj/ehr218.Google Scholar
Silversides, CK, Grewal, J, Mason, J, et al. Pregnancy outcomes in women with heart disease: the CARPREG II study. J Am Coll Cardiol 2018; 71: 2419–30. doi: 10.1016/j.jacc.2018.02.076.CrossRefGoogle ScholarPubMed
Lindheimer, M, Katz, A. Sodium and diuretics in pregnancy. N Engl J Med 1973; 288: 891–4.Google Scholar
Seitchik, J. Total body water and total body density of pregnant women. Obstet Gynecol 1967; 29: 155–6.Google Scholar
Theunissen, I, Parer, J. Fluid and electrolytes in pregnancy. Clin Obstet Gynecol 1994; 37: 315.CrossRefGoogle ScholarPubMed
Scott, DE. Anemia in pregnancy. Obstet Gynecol Annu 1972; 1: 219–44.Google Scholar
Pritchard, JA, Baldwin, RM, Dickey, JC, Wiggins, KM. Blood volume changes in pregnancy and the puerperium: 2. Red blood cell loss and changes in apparent blood volume during and following vaginal delivery, cesarean section, and cesarean section plus total hysterectomy. Am J Obstet Gynecol 1962; 84: 1271–82.Google Scholar
Bader, RA, Bader, ME, Rose, DF, Braunwald, E. Hemodynamics at rest and during exercise in normal pregnancy as studied by cardiac catheterization. J Clin Invest 1955; 34: 1524–36.CrossRefGoogle Scholar
Desai, D, Moodley, J, Naidoo, DP. Echocardiographic assessment of cardiovascular hemodynamics in normal pregnancy. Obstet Gynecol 2004; 104: 20–9.Google Scholar
Katz, R, Karliner, JS, Resnik, R. Effects of a natural volume overload state (pregnancy) on left ventricular performance in normal human subjects. Circulation 1978; 58: 434–41.Google Scholar
Ueland, K, Novy, MJ, Peterson, EN, Metcalfe, J. Maternal cardiovascular dynamics: IV. The influence of gestational age on the maternal cardiovascular response to posture and exercise. Am J Obstet Gynecol 1969; 104: 856–64.Google Scholar
Sadaniantz, A, Kocheril, AG, Emaus, SP, Garber, CE, Parisi, AF. Cardiovascular changes in pregnancy evaluated by two-dimensional and Doppler echocardiography. J Am Soc Echocardiogr 1992; 5: 253–8.Google Scholar
Wilson, M, Morganti, AA, Zervoudakis, I, et al. Blood pressure, the renin-aldosterone system, and sex steroids throughout normal pregnancy. Am J Med 1980; 68: 97104.CrossRefGoogle ScholarPubMed
MacGillivray, I, Rose, GA, Rowe, B. Blood pressure survey in pregnancy. Clin Sci 1969; 37: 395407.Google Scholar
Kerr, M. Cardiovascular dynamics in pregnancy and labour. Br Med Bull 1968; 24: 1924.Google Scholar
Kim, T, Ryu, D. The effect of fundal pressure at caesarean section on maternal haemodynamics. Anesthesia 2006; 61: 434–8.CrossRefGoogle ScholarPubMed
Oian, P, Maltau, JM, Noddeland, H, Fadnes, HO. Oedema-preventing mechanisms in subcutaneous tissue of normal pregnant women. Br J Obstet Gynaecol 1985; 92: 1113–19.Google Scholar
Oian, P, Maltau, J. Calculated capillary hydrostatic pressure in normal pregnancy and preeclampsia. Am J Obstet Gynecol 1987; 157: 102–6.Google Scholar
Cotton, DB, Gonik, B, Spillman, T, Dorman, KF. Intrapartum to postpartum changes in colloid osmotic pressure. Am J Obstet Gynecol 1984; 149: 174–7.CrossRefGoogle ScholarPubMed
Gonik, B, Cotton, D, Spillman, T, Abouleish, E, Zavisca, F. Peripartum colloid osmotic changes: effects of controlled fluid management. Am J Obstet Gynecol 1985; 151: 812–15.Google Scholar
Wilson, W, Taubert, KA, Gewitz, M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2007; 116: 1736–54.Google Scholar
National Institute for Health and Care Excellence. Prophylaxis Against Infective Endocarditis: Antimicrobial Prophylaxis Against Infective Endocarditis in Adults and Children Undergoing Interventional Procedures. NICE Clinical guideline CG64. London: NICE, 2008 [updated 2016]. www.nice.org.uk/guidance/CG64 (accessed August 2020).Google Scholar
Gould, FK, Elliott, TS, Foweraker, J, et al. Guidelines for the prevention of endocarditis: report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrob Chemother 2006; 57: 1035–42.CrossRefGoogle ScholarPubMed
Smaill, FM, Gyte, GM. Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section. Cochrane Database Syst Rev 2010 (1): CD007482.Google Scholar
McFaul, PB, Dornan, JC, Lamki, H, Boyle, D. Pregnancy complicated by maternal heart disease: a review of 519 women. Br J Obstet Gynaecol 1988; 95: 861–7.Google Scholar
Sugrue, D, Blake, S, MacDonald, D. Pregnancy complicated by maternal heart disease at the National Maternity Hospital, Dublin, Ireland, 1969–1978. Am J Obstet Gynecol 1981; 139: 16.Google Scholar
Durack, D. Prevention of infective endocarditis. N Engl J Med 1995; 332: 3844.Google Scholar
Nishimura, RA, Otto, CM, Bonow, RO, et al. 2017 AHA/ACC focused update of the 2014 AHA/ACC Guideline for the management of patient with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation 2017; 135: e1159−95. https://doi.org/10.1161/CIR.0000000000000503.Google Scholar
Pocock, S, Chen, K. Inappropriate use of antibiotic prophylaxis to prevent infective endocarditis in obstetric patients. Obstet Gynecol 2006; 108: 280–5.Google Scholar
Gelson, E, Curry, R, Gatzoulis, MA, et al. Effect of maternal heart disease on fetal growth. Obstet Gynecol 2011; 117: 886–91.Google Scholar
Task Force on the Management of Cardiovascular Diseases During Pregnancy of the European Society of Cardiology. Expert consensus document on management of cardiovascular diseases during pregnancy. Eur Heart J 2003; 24: 761–81.Google Scholar
Burn, J, Brennan, P, Little, J, et al. Recurrence risks in offspring of adults with major heart defects: results from first cohort of British collaborative study. Lancet 1998; 351: 311–16.Google Scholar
Cheitlin, D, Alpert, JS, Armstrong, WF, et al. ACC/AHA guidelines for the clinical application of echocardiography: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Clinical Application of Echocardiography). Developed in collaboration with the American Society of Echocardiography Circulation 1997; 95: 1686–744.Google Scholar
Criteria Committee of the New York Heart Association. Nomenclature and Criteria for Diagnosis of Disease of the Heart and Great Vessels. 6th edn. Boston, MA: Little, Brown, 1964.Google Scholar
Sidlik, R, Sheiner, E, Levy, A, Wiznitzer, A. Effect of maternal congenital heart defects on labor and delivery outcome: a population-based study. J Matern Fetal Neonatal Med 2007; 20: 211–16.Google Scholar
Ostheimer, GW, Alper, MH. Intrapartum anesthetic management of the pregnant patient with heart disease. Clin Obstet Gynecol 197; 18: 81–97.Google Scholar
Briggs, G, Freeman, R, Yaffe, S. Drugs in Pregnancy and Lactation, 8th edn. Philadelphia, PA: Lippincott Williams & Wilkins, 2011.Google Scholar
Food and Drug Administration (FDA). Content and Format of Labeling for Human Prescription Drug and Biological Products; Requirements for Pregnancy and Lactation Labeling. Final Rule. Fed Regist 2014; 79 (233): 72063–103.Google Scholar
American College of Obstetricians and Gynecologists. ACOG Practice Bulletin No. 212: pregnancy and heart disease. Obstet Gynecol 2019; 133: e320−56. https://doi.org/10.1097/AOG.0000000000003243.Google Scholar
Hameed, AB, Morton, CH, Moore, A. Improving health care response to cardiovascular disease in pregnancy and postpartum. California Department of Public Health, 2017. www.cmqcc.org/resource/improving-health-care-response-cardiovascular-disease-pregnancy-and-postpartum (accessed August 2020).Google Scholar
Thorne, S. Pregnancy and native heart valve disease. Heart 2016; 102: 1410−17. https://doi.org/10.1136/heartjnl-2014-306729.Google Scholar
Robertson, JE, Silversides, CK, Mah, ML, et al. A contemporary approach to the obstetric management of women with heart disease. J Obstet Gynaecol Can 2012; 34: 812–19.Google Scholar
Bernard, GR, Sopko, G, Cerra, F, et al. Pulmonary artery catheterization and clinical outcomes: National Heart, Lung, and Blood Institute and Food and Drug Administration Workshop Report. JAMA 2000; 283: 2568–72.Google Scholar
Parson, P. Progress in research on pulmonary-artery catheters. N Engl J Med 2003; 348: 66–8.Google Scholar
Sandham, JD, Hull, RD, Brant, RF, et al. A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. N Engl J Med 2003; 348: 514.Google Scholar
Asfour, V, Murphy, MO, Attia, R. Is vaginal delivery or caesarean section the safer mode of delivery in patients with adult congenital heart disease? Interact Cardiovasc Thorac Surg 2013; 17: 144–50.Google Scholar
World Health Organization. Medical Eligibility Criteria for Contraceptive Use, 5th edn. Geneva: World Health Organization, 2015.Google Scholar
Thorne, S, Nelson-Piercy, C, MacGregor, A, et al. Pregnancy and contraception in heart disease and pulmonary arterial hypertension. J Fam Plann Reprod Health Care 2006; 32: 7581.Google Scholar
Goldberg, LM, Uhland, H. Heart murmurs in pregnancy: a phonocardiographic study and their development, progression and regression. Dis Chest 1967; 52: 381–6.Google Scholar
Harvey, W. Alterations of the cardiac physical examination in normal pregnancy. Clin Obstet Gynecol 1975; 18: 5163.Google Scholar
Northcote, R, Knight, P, Ballantyne, D. Systolic murmurs in pregnancy: value of echocardiographic assessment. Clin Cardiol 1985; 8: 327–8.Google Scholar
Etchells, E, Bell, C, Robb, K. Does this patient have an abnormal systolic murmur? JAMA 1997; 277: 564–71.Google Scholar
Xu, M, McHaffie, DJ. Nonspecific systolic murmurs: an audit of the clinical value of echocardiography. N Z Med J 1993; 106: 54–6.Google Scholar
Tan, J, de Swiet, M. Prevalence of heart disease diagnosed de novo in pregnancy in a West London population. Br J Obstet Gynaecol 1998; 105: 1185–8.Google Scholar
Bonow, RO, Carabello, BA, Kanu, C, et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. Circulation 2006; 114: e84–231.Google Scholar
Weisse, A. Mitral valve prolapse: now you see it; now you don’t: recalling the discovery, rise and decline of a diagnosis. Am J Cardiol 2007; 99: 129–33.Google Scholar
Freed, LA, Levy, D, Levine, RA, et al. Prevalence and clinical outcome of mitral-valve prolapse. N Engl J Med 1999; 341: 17.Google Scholar
Hepner, AD, Ahmadi-Kashani, M, Movahed, MR. The prevalence of mitral valve prolapse in patients undergoing echocardiography for clinical reason. Int J Cardiol 2007; 123: 55–7.Google Scholar
Lax, D, Eicher, M, Goldberg, S. Effects of hydration on mitral valve prolapse. Am Heart J 1993; 126: 415–18.Google Scholar
Rayburn, WF, LeMire, MS, Bird, JL, Buda, AJ. Mitral valve prolapse. J Reprod Med 1987; 32: 185–7.Google Scholar
Retchin, SM, Fletcher, RH, Earp, J, Lamson, N, Waugh, RA. Mitral valve prolapse: disease or illness? Arch Intern Med 1986; 146: 1081–4.Google Scholar
Avierinos, JF, Detaint, D, Messika-Zeitoun, D, Mohty, D, Enriquez-Sarano, M. Risk, determinants, and outcome implications of progression of mitral regurgitation after diagnosis of mitral valve prolapse in a single community. Am J Cardiol 2008; 101: 662–7.Google Scholar
Zuppiroli, A, Rinaldi, M, Kramer-Fox, R, et al. Natural history of mitral valve prolapse. Am J Cardiol 1995; 75: 1028–32.Google Scholar
Drenthen, W, Pieper, PG, Roos-Hesselink, JW, et al. Outcome of pregnancy in women with congenital heart disease: a literature review. J Am Coll Cardiol 2007; 49: 2303–11.Google Scholar
Karamlou, T, Diggs, BS, McCrindle, BW, Welke, KF, et al. A growing problem: maternal death and peripartum complicatons are higher in women with grown-up congenital heart disease. Ann Thorac Surg 2011; 92: 2193–9.Google Scholar
Webb, G, Gatzoulis, M. Atrial septal defects in the adult: recent progress and overview. Circulation 2006; 114: 1645–53.Google Scholar
Alahuhta, S, Jouppila, P. Pregnancy after cardiac surgery in patients with secondary pulmonary hypertension due to a ventricular septal defect. Acta Obstet Gynecol Scand 1994; 73: 836–8.CrossRefGoogle ScholarPubMed
Curry, RA, Fletcher, C, Gelson, E, et al. Pulmonary hypertension and pregnancy: a review of 12 pregnancies in nine women. BJOG 2012; 119: 752–61.Google Scholar
Duarte, AG, Thomas, S,Safdar, Z, et al. Management of pulmonary arterial hypertension during pregnancy: a retrospective, multicenter experience. Chest 2013; 143: 1330–6.Google Scholar
Sliwa, K, van Hagen, IM, Budts, W, et al. Pulmonary hypertension and pregnancy outcomes: data from the Registry of Pregnancy and Cardiac Disease (ROPAC) of the Euproean Society of Cardiology. Eur J Heart Fail 2016; 18: 1119–28. https://doi.org/10.1002/ejhf.594.CrossRefGoogle ScholarPubMed
Chakravarty, E, Khanna, D, Chung, L. Pregnancy outcomes in systemic sclerosis, primary pulmonary hypertension, and sickle cell disease. Obstet Gynecol 2008; 111: 927–34.Google Scholar
Penning, S, Robinson, KD, Major, CA, Garite, TJ. A comparison of echocardiography and pulmonary artery catheterization for evaluation of pulmonary artery pressures in pregnant patients with suspected pulmonary hypertension. Am J Obstet Gynecol 2001; 184: 1568–70.Google Scholar
Wylie, BJ, Epps, KC, Gaddipati, S, Waksmonski, CA. Correlation of transthoracic echocardiography and right heart catheterization in pregnancy. J Perinat Med 2007; 35: 497502.Google Scholar
Bonnin, M, Mercier, FJ, Sitbon, O, et al. Severe pulmonary hypertension during pregnancy mode of delivery and anesthetic management of 15 consecutive cases. Anesthesiology 2005; 102: 1133–7.Google Scholar
Maxwell, BG, El-Sayed, YY, Riley, ET, Carvalho, B. Peripartum outcomes and anaesthetic management of parturients with moderate to complex heart disease or pulmonary hypertension. Anesthesia 2013; 68: 52–9.Google Scholar
Hart, C. Nitric oxide in adult lung disease. Chest 1999; 115: 1407–17.CrossRefGoogle ScholarPubMed
Yentis, SM, Steer, PJ, Plaat, F. Eisenmenger’s syndrome in pregnancy: maternal and fetal mortality in the 1990s. Br J Obstet Gynaecol 1998; 105: 921–2.Google Scholar
Vongpatanasin, W, Brickner, ME, Hillis, LD, Lange, RA. The Eisenmenger syndrome in adults. Ann Intern Med 1998; 128: 745–55.Google Scholar
Smedstad, K, Cramb, R, Morison, D. Pulmonary hypertension and pregnancy: A series of eight cases. Can J Anaesth 1994; 41: 502–12.CrossRefGoogle ScholarPubMed
Hameed, A, Goodwin, T, Elkayam, U. Effect of pulmonary stenosis on pregnancy outcomes: a case–control study. Am Heart J 2007; 154: 852–4.Google Scholar
Drenthen, W, Pieper, PG, Roos-Hesselink, JW, et al. Non-cardiac complications during pregnancy in women with isolated congenital pulmonary valvar stenosis. Heart 2006; 92: 1838–43.Google Scholar
Hameed, A, Karaalp, IS, Tummala, PP, et al. The effect of valvular heart disease on maternal and fetal outcome of pregnancy. J Am Coll Cardiol 2001; 37: 893–9.Google Scholar
Vriend, JW, Drenthen, W, Pieper, PG, et al. Outcome of pregnancy in patients after repair of aortic coarctation. Eur Heart J 2005; 26: 2173–8.Google Scholar
Horlick, EM, McLaughlin, PR, Bensen, LN. The adult with repaired coarctation of the aorta. Curr Cardiol Rep 2007; 9: 323–30.Google Scholar
Krieger, EV, Landzberg, MJ, Economy, KE, Webb, GD, Opotowsky, AR. Comparison of risk of hypertensive complications of pregnancy among women with versus without coarctation of the aorta. Am J Cardiol 2011; 107: 1529–34.Google Scholar
Beauschesne, LM, Connolly, HM, Ammash, NM, Warnes, CA. Coarctation of the aorta: outcome of pregnancy. J Am Coll Cardiol 2001; 38: 1728–33.Google Scholar
Gelson, E, Gatzoulis, M, Steer, PJ, Lupton, M, Johnson, M. Tetralogy of Fallot: maternal and neonatal outcomes. BJOG 2008; 115: 398402.Google Scholar
Meijer, JM, Pieper, PG, Drenthen, W, et al. Pregnancy, fertility, and recurrence risk in corrected tetralogy of Fallot. Heart 2005; 91: 801–5.Google Scholar
Patton, DE, Lee, W, Cotton, DB, et al. Cyanotic maternal heart disease in pregnancy. Obstet Gynecol Surv 1990; 45: 594600.Google Scholar
Canobbio, MM, Morris, CD, Graham, TP, Landzberg, MJ. Pregnancy outcomes after atrial repair for transposition of the great arteries. Am J Cardiol 2006; 98: 668–72.Google Scholar
Jain, VD, Moghbeli, N, Webb, G, et al. Pregnancy in women with congenital heart disease: the impact of a systemic right ventricle. Congenit Heart Dis 2011; 6: 147–56.Google Scholar
Bowater, SE, Selman, TJ, Hudsmith, LE, et al. Long-term outcome following pregnancy in women with a systemic right ventricle: is the deterioration due to pregnancy or a consequence of time? Congenit Heart Dis 2013; 8: 302–7.Google Scholar
Tobler, D, Fernandes, SM, Wald, RM, et al. Pregnancy outcomes in women with transposition of the great arteries and arterial switch operation. Am J Cardiol 2010; 106: 417–20.Google Scholar
Horiuchi, C, Kamiya, CA, Ohuchi, H, et al. Pregnancy outcomes and mid-term prognosis in women after arterial switch operation for dextro-transposition of the great arteries: tertiary hospital experiences and review of the literature. J Cardiol 2019; 73: 247–54. https://doi.org/10.1016/j.jjcc.2018.11.007.Google Scholar
Stoll, VM, Drury, NE, Thorne, S, et al. Pregnancy outcomes in women with transposition of the great arteries after an arterial switch operation. JAMA Cardiol 2018; 3: 1119–22. https://doi.org/10.1001/jamacardio.2018.2747.CrossRefGoogle ScholarPubMed
Katsuragi, S, Kamiya, C, Yamanaka, K, et al. Risk factors for maternal and fetal outcome in pregnancy complicated by Ebstein anomaly. Am J Obstet Gynecol 2013; 209: 452.e1–6.Google Scholar
Paranon, S, Acar, P. Ebstein’s anomaly of the tricuspid valve: from fetus to adult. Heart 2008; 94: 237–43.Google Scholar
Friedman, W, Heiferman, M. Clinical problems of postoperative pulmonary vascular disease. Am J Cardiol 1982; 50: 631–6.Google Scholar
Wilson, N. Rheumatic heart disease in indigenous populations: New Zealand experience. Heart Lung Circ 2010; 19: 282–8.Google Scholar
Elassy, S, Elmidany, A, Elbawab, H. Urgent cardiac surgery during pregnancy: a continous challenge. Ann Thorac Surg, 2014; 97: 1624–9.Google Scholar
Sartain, JB, Anderson, NL, Barry, JJ, Boyd, PT, Howat, PW. Rheumatic heart disease in pregnancy: cardiac and obstetric outcomes. Intern Med J 2012; 42: 978–84.Google Scholar
Gray, ED, Regelmann, WE, Abdin, Z, et al. Compartmentalization of cells surface antigens in peripheral blood and tonsils in rheumatic heart disease. J Infect Dis 1987; 155: 247252.Google Scholar
van Hagen, IM, Thorne, SA, Taha, N, et al. Pregnancy outcomes in women with rheumatic mitral valve disease: results from the registry of pregnancy and cardiac disease. Circulation 2018; 137: 806–16. https://doi.org/10.1161/CIRCULATIONAHA.117.032561.Google Scholar
Desai, DK, Adanlawo, M, Naidoo, DP, Moodley, J, Kleinschmidt, I. Mitral stenosis in pregnancy: a four-year experience at King Edward VIII Hospital, Durban, South Africa. BJOG 2000; 107: 953–8.Google Scholar
Silversides, CK, Colman, JM, Sermer, M, Siu, SC. Cardiac risk in pregnant women with rheumatic mitral stenosis. Am J Cardiol 2003; 91: 1382–5.Google Scholar
Lesniak-Sobelga, A, Tracz, W, Kostkiewicz, M, Podolec, P, Pasowicz, M. Clinical and echocardiographic assessment of pregnant women with valvular heart diseases: maternal and fetal outcome. Int J Cardiol 2004; 94: 1523.Google Scholar
Nishimura, RA, Otto, CM, Bonow, RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary. J Am Coll Cardiol 2014; 63: 2438–88.Google Scholar
de Souza, JA, Martinez, EE, Ambrose, JA, et al. Percutaneous balloon mitral valvuloplasty in comparison with open mitral valve commissurotomy for mitral stenosis during pregnancy. J Am Coll Cardiol 2001; 37: 900–3.CrossRefGoogle ScholarPubMed
Fawzy, ME, Kinsara, AJ, Stefadouros, M, et al. Long-term outcome of mitral balloon valvotomy in pregnant women. J Heart Valve Dis 2001; 10: 153–7.Google Scholar
Esteves, C, Munoz, JS, Braga, S, et al. Immediate and long-term follow-up of percutaneous balloon mitral valvuloplasty in pregnant patients with rheumatic mitral stenosis. Am J Cardiol 2006; 98: 812–16.Google Scholar
Nercolini, D, da Rocha Loures Bueno, R, Eduardo Guérios, E, et al. Percutaneous mitral balloon valvuloplasty in pregnant women with mitral stenosis. Catheter Cardiovasc Interv 2002; 57: 318–22.Google Scholar
Sivadasanpillai, H, Srinivasan, A, Sivasubramoniam, S, et al. Long-term outcome of patients undergoing balloon mitral valvotomy in pregnancy. Am J Cardiol 2005; 95: 1504–6.CrossRefGoogle ScholarPubMed
Iscan, ZH, Mavioglu, L, Vural, KM, Kucuker, S, Birincioglu, L. Cardiac surgery during pregnancy. J Heart Valve Dis 2006; 15: 686–90.Google Scholar
Kinsara, AJ, Ismail, O, Fawzi, ME. Effect of balloon mitral valvoplasty during pregnancy and childhood development. Cardiology 2002; 97: 155–8.CrossRefGoogle ScholarPubMed
Clark, SL, Phelan, JP, Greenspoon, J, Aldahl, D, Horenstein, J. Labor and delivery in the presence of mitral stenosis: central hemodynamic observations. Am J Obstet Gynecol 1985; 152: 984–8.Google Scholar
Waller, B, Howard, J, Fess, S. Pathology of mitral valve stenosis and pure mitral regurgitation: Part I. Clin Cardiol 1994; 17: 330–6.Google Scholar
John, AS, Gurley, F, Schaff, HV, et al. Cardiopulmonary bypass during pregnancy. Ann Thorac Surg 2011; 91: 1191–6.Google Scholar
Mahli, A, Izdes, S, Coskun, D. Cardiac operations during pregnancy: review of factors influencing fetal outcome. Ann Thorac Surg 2000; 69: 1622–6.Google Scholar
Rossouw, GJ, Knott-Craig, CJ, Barnard, PM, Macgregor, LA, Van Zyl, WP. Intracardiac operation in seven pregnant women. Ann Thorac Surg 1993; 55: 1172–4.Google Scholar
Weiss, BM, von Segesser, LK, Alon, E, Seifert, B, Turina, MI. Outcome of cardiovascular surgery and pregnancy: a systematic review of the period 1984–1996. Am J Obstet Gynecol 1998; 179: 1643–53.Google Scholar
Carabello, BA. Aortic stenosis. N Engl J Med 2002; 346: 677–82.Google Scholar
Silversides, CK, Colman, JM, Sermer, M, Farine, D, Siu, SC. Early and intermediate-term outcomes of pregnancy with congenital aortic stenosis. Am J Cardiol 2003; 91: 1386–9.Google Scholar
Yap, SC, Drenthen, W, Pieper, PG, et al. Risk of complications during pregnancy in women with congenital aortic stenosis. Int J Cardiol 2008; 126: 240–6.Google Scholar
Spagnuolo, M, Kloth, H, Taranta, A, Doyle, E, Pasternack, B. Natural history of rheumatic aortic regurgitation. Criteria predictive of death, congestive heart failure, and angina in young patients. Circulation 1971; 44: 368–80.Google Scholar
Szekely, P, Turner, R, Snaith, L. Pregnancy and the changing pattern of rheumatic heart disease. Br Heart J 1973; 35: 1293–303.Google Scholar
Vongpatansin, W, Hillis, L, Lange, R. Prosthetic heart valves. N Engl J Med 1996; 335: 407–16.Google Scholar
Yap, SC, Drenthen, W, Pieper, PG, et al. Outcome of pregnancy in women after pulmonary autograft valve replacement for congenital aortic valve disease. J Heart Valve Dis 2007; 16: 398403.Google Scholar
De Santo, LS, Romano, G, Della Corte, A, et al. Mitral mechanical replacement in young rheumatic women: analysis of long-term survival, valve-related complications, and pregnancy outcomes over a 3707-patient-year follow-up. J Thorac Cardiovasc Surg 2005; 130: 1319.Google Scholar
Elkayam, U, Bitar, F. Valvular heart disease and pregnancy part II: prosthetic valves. J Am Coll Cardiol 2005; 46: 403–10.Google Scholar
Kearon, C, Hirsh, J. Management of anticoagulation before and after elective surgery. N Engl J Med 1997; 336: 1506–11.Google Scholar
Bouhout, I, Poirier, N, Mazine, A, et al. Cardiac, obstetric, and fetal outcomes during pregnancy after biological or mechanical aortic valve replacement. Can J Cardiol 2014; 30: 801–7.Google Scholar
Sillesen, M, Hjortdal, V, Vejlstrup, N, Sørensen, K. Pregnancy with prosthetic heart valves: 30 years nationwide experience in Denmark. Eur J Cardiothorac Surg 2011; 40: 448–54.Google Scholar
Cotrufo, M, De Feo, M, De Santo, LS, et al. Risk of warfarin during pregnancy with mechanical valve prostheses. Obstet Gynecol 2002; 99: 3540.Google Scholar
Sadler, L, McCowan, L, White, H, et al. Pregnancy outcomes and cardiac complications in women with mechanical, bioprosthetic and homograft valves. BJOG 2000; 107: 245–53.Google Scholar
Heuvelman, HJ, Arabkhani, B, Cornette, JM, et al. Pregnancy outcomes in women with aortic valve substitutes. Am J Cardiol 2013; 111: 382–7.Google Scholar
Salazar, E, Espinola, N, Román, L, Casanova, JM. Effect of pregnancy on the duration of bovine pericardial bioprostheses. Am Heart J 1999; 137: 714–20.Google Scholar
North, RA, Sadler, L, Stewart, AW, et al. Long-term survival and valve-related complications in young women with cardiac valve replacements. Circulation 1999; 99: 2669–76.Google Scholar
van Hagen, IM, Roos-Hesselink, JW, Ruys, TP, et al. Pregnancy in women with a mechanical heart valve: data of the European Society of Cardiology Registry of Pregnancy and Cardiac Disease (ROPAC). Circulation 2015; 132: 132–42. https://doi.org/10.1161/CIRCULATIONAHA.115.015242.Google Scholar
Oran, B, Lee-Parritz, A, Ansell, J. Low molecular weight heparin for the prophylaxis of thromboembolism in women with prosthetic mechanical heart valves during pregnancy. Thromb Haemost 2004; 92: 747–51.Google Scholar
Saeed, CR, Frank, JB, Pravin, M, et al. A prospective trial showing the safety of adjusted-dose enoxaparin for thromboprophylaxis of pregnant women with mechanical prosthetic heart valves. Clin Appl Thromb Hemost 2011; 17: 313–19.Google Scholar
De Santo, LS, Romano, G, Della Corte, A, et al. Mechanical aortic valve replacement in young women planning on pregnancy maternal and fetal outcomes under low oral anticoagulantion, a pilot observational study on a comprehensive pre-operative counseling protocol. J Am Coll Cardiol 2012; 59: 1110–15.Google Scholar
Vural, KM, Ozatik, MA, Uncu, H, et al. Pregnancy after mechanical mitral valve replacement. J Heart Valve Dis 2003; 12: 370–6.Google Scholar
Ginsberg, JS, Hirsch, J. Use of antithrombotic agents during pregnancy. Chest 1998; 114 (5 Suppl): 524S530S.Google Scholar
Bates, SM, Greer, IA, Middeldorp, S, et al. VTE, thrombophilia, antithrombotic therapy, and pregnancy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141 (2 Suppl): 691S736S.Google Scholar
Bardett-Fausett, MB, Vogtlander, M, Lee, RM, et al. Heparin-induced thrombocytopenia is rare in pregnancy. Am J Obstet Gynecol 2001; 185: 148–52.Google Scholar
Leffert, L, Butwick, A, Carvalho, B, et al. The Society for Obstetric Anesthesia and Perinatology Consensus Statement on the anesthetic management of pregnant and postpartum women receiving thromboprophylaxis or higher dose anticoagulants. Anesth Analg 2018; 126: 928–44. https://doi.org/10.1213/ANE.0000000000002530.Google Scholar
Milewicz, D, Dietz, H, Miller, D. Treatment of aortic disease in patients with Marfan syndrome. Circulation 2005; 111: e150–7.CrossRefGoogle ScholarPubMed
Rossiter, JP, Repke, JT, Morales, AJ, Murphy, EA, Pyeritz, RE. A prospective longitudinal evaluation of pregnancy in the Marfan syndrome. Am J Obstet Gynecol 1995; 173: 1599–606.Google Scholar
Curry, RA, Gelson, E, Swan, L, et al. Marfan syndrome and pregnancy: maternal and neonatal outcomes. BJOG 2014; 121: 610–17.Google Scholar
Dean, JC. Management of Marfan syndrome. Heart 2002; 88: 97103.Google Scholar
Meijboom, LJ, Vos, FE, Timmermans, J, et al. Pregnancy and aortic root growth in the Marfan syndrome: a prospective study. Eur Heart J 2005; 26: 914–20.Google Scholar
Meijboom, LJ, Drenthen, W, Pieper, PG, et al. Obstetric complications in Marfan syndrome. Int J Cardiol 2006; 110: 53–9.Google Scholar
Pearson, GD, Veille, JC, Rahimtoola, S, et al. Peripartum cardiomyopathy: National Heart, Lung, and Blood Institute and Office of Rare Diseases (National Institutes of Health) workshop recommendations and review. JAMA 2000; 283: 1183–8.Google Scholar
Fett, JD, Christie, LG, Carraway, RD, Murphy, JG. Five-year prospective study of the incidence and prognosis of peripartum cardiomyopathy at a single institution. Mayo Clin Proc 2005; 12: 1602–6.Google Scholar
Brar, SS, Khan, SS, Sandhu, GK, et al. Incidence, mortality, and racial differences in peripartum cardiomyopathy. Am J Cardiol 2007; 100: 302–4.Google Scholar
Mielniczuk, LM, Williams, K, Davis, DR, et al. Frequency of peripartum cardiomyopathy. Am J Cardiol 2006; 97: 1765–8.Google Scholar
Whiteman, VE, Salihu, HM, Weldeselasse, HE, et al. Temporal trends in cardiomyopathy in pregnancy and association with feto-infant morbidity outcomes. J Matern Fetal Neonatal Med 2012; 25: 627–31.Google Scholar
Bültmann, BD, Klingel, K, Näbauer, M, Wallwiener, D, Kandolf, R. High prevalence of viral genomes and inflammation in peripartum cardiomyopathy. Am J Obstet Gynecol 2005; 193: 363–5.Google Scholar
Fett, JD, Dowell, DL, Carraway, RD, Sundstrom, JB, Ansari, AA. One hundred cases of peripartum cardiomyopathy. . . and counting: what is going on? Int J Cardiol 2004; 97: 571–3.Google Scholar
Lamparter, S, Pankuweit, S, Maisch, B. Clinical and immunologic characteristics in peripartum cardiomyopathy. Int J Cardiol 2007; 118: 1420.Google Scholar
Sliwa, K, Förster, O, Libhaber, E, et al. Peripartum cardiomyopathy: inflammatory markers as predictors of outcome in 100 prospectively studied patients. Eur Heart J 2006; 27: 441–6.Google Scholar
Sliwa, K, Fett, J, Elkayam, U. Peripartum cardiomyopathy. Lancet 2006; 368: 687–93.Google Scholar
Bello, N, Rendon, I, Arany, Z. The relationshiop between pre-eclampsia and peripartum cardiomyopathy: a systematic review and meta-analysis. J Am Coll Cardiol 2013; 62: 1715–23.Google Scholar
Elkayam, U, Akhter, MW, Singh, H, et al. Pregnancy-associated cardiomyopathy clinical characteristics and a comparison between early and late presentation. Circulation 2005; 111: 2050–5.Google Scholar
Amos, AM, Jaber, WA, Russell, SD. Improved outcomes in peripartum cardiomyopathy with contemporary. Am Heart J 2006; 152: 509–13.Google Scholar
Chapa, JB, Heiberger, HB, Weinert, L, et al. Prognostic value of echocardiography in peripartum cardiomyopathy. Obstet Gynecol 2005; 105: 1303–8.Google Scholar
Duran, N, Günes, H, Duran, I, Biteker, M, Ozkan, M. Predictors of prognosis in patients with peripartum cardiomyopathy. Int J Gynaecol Obstet 2008; 101: 137–40.Google Scholar
Habli, M, O’Brien, T, Nowack, E, et al. Peripartum cardiomyopathy: prognostic factors for long-term maternal outcome. Am J Obstet Gynecol 2008; 199: 415.e1–5.Google Scholar
Elkayam, U, Tummala, PP, Rao, K, et al. Maternal and fetal outcomes of subsequent pregnancies in women with peripartum cardiomyopathy. N Engl J Med 2001; 344: 1567–71.Google Scholar
Fett, J, Christie, L, Murphy, J. Outcomes of subsequent pregnancy after peripartum cardiomyopathy: a case series from Haiti. Ann Intern Med 2006; 145: 30–4.Google Scholar
Sliwa, K, Forster, O, Zhanje, F, et al. Outcome of subsequent pregnancy in patients with documented peripartum cardiomyopathy. Am J Cardiol 2004; 93: 1441–3.Google Scholar
Lampert, MB, Weinert, L, Hibbard, J, et al. Contractile reserve in patients with peripartum cardiomyopathy and recovered left ventricular function. Am J Obstet Gynecol 1997; 176: 189–95.CrossRefGoogle ScholarPubMed
Shotan, A, Ostrzega, E, Mehra, A, Johnson, JV, Elkayam, U. Incidence of arrhythmias in normal pregnancy and relation to palpitations, dizziness, and syncope. Am J Cardiol 1997; 79: 1061–4.Google Scholar
Blomström-Lundqvist, C, Scheinman, MM, Aliot, EM, et al. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias). Circulation 2003; 108: 1871–909.Google Scholar
Romem, A, Romem, Y, Katz, M, Battler, A. Incidence and characteristics of maternal cardiac arrhythmias during labor. Am J Cardiol 2004; 93: 931–3.Google Scholar
Berlinerblau, R, Yessian, A, Lichstein, E, et al. Maternal arrhythmias of normal labor and delivery. Gynecol Obstet Invest 2001; 52: 128–31.Google Scholar
Rashba, EJ, Zareba, W, Moss, AJ, et al. Influence of pregnancy on the risk for cardiac events in patients with hereditary long QT syndrome. Circulation 1998; 97: 451–6.Google Scholar
Tan, H, Lie, K. Treatment of tachyarrhythmias during pregnancy and lactation. Eur Heart J 2001; 22: 458–64.Google Scholar
Silversides, CK, Harris, L, Haberer, K, et al. Recurrence rates of arrhythmias during pregnancy in women with previous tachyarrhythmia and impact on fetal and neonatal outcomes. Am J Cardiol 2006; 97: 1206–12.Google Scholar
Heradien, MJ, Goosen, A, Crotti, L, et al. Does pregnancy increase cardiac risk for LQT1 patients with the KCNQ1-A341V mutation? J Am Coll Cardiol 2006; 48: 1410–15.Google Scholar
Ersbøll, AS, Hedegaard, M, Søndergaard, L, Ersbøll, M, Johansen, M. Treatment with oral beta-blockers during pregnancy complicated by maternal heart disease increased the risk of fetal growth restriction. BJOG 2014; 121: 618–26.Google Scholar
Wang, YC, Chen, CH, Su, HY, Yu, MH. The impact of maternal cardioversion on fetal haemodynamics. Eur J Obstet Gynecol Reprod Biol 2006; 126: 268–9.Google Scholar
Fuster, V, Rydén, LE, Asinger, RW, et al. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary. Circulation 2001; 104: 2118–50.Google Scholar
James, AH, Jamison, MG, Biswas, MS, et al. Acute myocardial infarction in pregnancy: a United States population-based study. Circulation 2006; 113: 1564–71.Google Scholar
Ladner, H, Danielsen, B, Gilbert, W. Acute myocardial infarction in pregnancy and the puerperium: a population-based study. Obstet Gynecol 2005; 105: 480–4.Google Scholar
Roth, A, Elkayam, U. Acute myocardial infarction associated with pregnancy. J Am Coll Cardiol 2008; 52: 171–80.Google Scholar
Karpati, P, Rossignol, M, Pirot, M, et al. High incidence of myocardial ischemia during postpartum hemorrhage. Anesthesiology 2004; 100: 30–6.Google Scholar
Elkayam, U, Jalnapurkar, S, Barakkat, MN, et al. Pregnancy-associated acute myocardial infarction: a review of contemporary experience in 150 cases between 2006 and 2011. Circulation 2014; 129: 1695–702. https://doi.org/10.1161/CIRCULATIONAHA.113.002054.Google Scholar
Abramov, Y, Abramov, D, Abrahamov, A, Durst, R, Schenker, J. Elevation of serum creatine phosphokinase and its MB isoenzyme during normal labor and early puerperium. Acta Obstet Gynecol Scand 1996; 75: 255–60.Google Scholar
Shivvers, S, Wians, FH, Keffer, JH, Ramin, SM. Maternal cardiac troponin I levels during normal labor and delivery. Am J Obstet Gynecol 1999; 180: 122.Google Scholar
Krahenmann, F, Huch, A, Atar, D. Troponin I measurement in the diagnosis of myocardial injury during pregnancy and delivery: two cases. Am J Obstet Gynecol 2000; 183: 1308–10.Google Scholar
Shade, GH, Ross, G, Bever, FN, et al. Troponin I in the diagnosis of acute myocardial infarction in pregnancy, labor, and post partum. Am J Obstet Gynecol 2002; 187: 1719–20.Google Scholar
Mhyre, JM, Tsen, LC, Einav, S, et al. Cardiac arrest during hospitalization for delivery in the United States, 1998–2011. Anesthesiology 2014; 120: 810–18.Google Scholar
Vinatier, D, Virelizier, S, Depret-Mosser, S, et al. Pregnancy after myocardial infarction. Eur J Obstet Gynecol Reprod Biol 1994; 56: 8993.Google Scholar
Jeejeebhoy, FM, Zelop, CM, Lipman, S, et al. Cardiac arrest in pregnancy: a scientific statement from the American Heart Association. Circulation 2015; 132: 1747–73. https://doi.org/10.1161/CIR.0000000000000300.Google Scholar
Katz, V, Balderston, K, DeFreest, M. Perimortem cesarean delivery: were our assumptions correct? Am J Obstet Gynecol 2005; 192: 1916–21.Google Scholar
Lipman, S, Cohen, S, Einav, S, et al. The Society for Obstetric Anesthesia and Perinatology consensus statement on the management of cardiac arrest in pregnancy. Anesth Analg 2014; 118: 1003–16.Google Scholar
Fisher, N, Eisen, LA, Bayya, JV, et al. Improved performance of maternal-fetal medicine staff after maternal cardiac arrest simulation-based training. Am J Obstet Gynecol 2011; 205: 239.e1–5.Google Scholar
Maron, BJ. Hypertrophic cardiomyopathy: a systematic review. JAMA 2002; 287: 1308–20.Google Scholar
Maki, S, Ikeda, H, Muro, A, et al. Predictors of sudden cardiac death in hypertrophic cardiomyopathy. Am J Cardiol 1998; 82: 774–8.Google Scholar
Deb, SJ, Schaff, HV, Dearani, JA, Nishimura, RA, Ommen, SR. Septal myectomy results in regression of left ventricular hypertrophy in patients with hypertrophic obstructive cardiomyopathy. Ann Thorac Surg 2004; 78: 2118–22.Google Scholar
Natale, A, Davidson, T, Geiger, MJ, Newby, K. Implantable cardioverter-defibrillators and pregnancy: a safe combination? Circulation 1997; 96: 2808–12.Google Scholar
Autore, C, Conte, MR, Piccininno, M, et al. Risk associated with pregnancy in hypertrophic cardiomyopathy. J Am Coll Cardiol 2002; 40: 1864–9.Google Scholar
Thaman, R, Varnava, A, Hamid, MS, et al. Pregnancy related complications in women with hypertrophic cardiomyopathy. Heart 2003; 89: 752–6.Google Scholar

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